2 Formyl 5 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Formyl-5-methylpyridine

    Specifications

    HS Code

    894171

    Chemical Formula C7H7NO
    Molar Mass 121.14 g/mol
    Appearance A colorless to pale yellow liquid
    Boiling Point 212 - 214 °C
    Density 1.092 g/cm³
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
    Flash Point 91 °C
    Odor Characteristic odor
    Cas Number 1122-71-0

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    General Information
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    Frequently Asked Questions

    As a leading 2-Formyl-5-methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Formyl-5-methylpyridine?
    2-formyl-5-methylpyridine is one of the organic compounds. It has a wide range of uses and is important in many fields.
    In the field of medicinal chemistry, it is often a key intermediate. Due to the special structure of this compound, various biologically active drug molecules can be prepared through various chemical reactions. For example, by condensing with specific amine compounds, it can construct a heterocyclic system with potential pharmacological activity, or can be used to develop antibacterial, antiviral and even anti-tumor drugs.
    In the field of materials science, 2-formyl-5-methylpyridine is also of great value. It can participate in the construction of functional materials, such as in the preparation of organic Light Emitting Diode (OLED) materials, using this as a starting material, through chemical modification, endow the material with unique optical properties, and improve the luminous efficiency and stability of OLED devices.
    Furthermore, in the field of organic synthetic chemistry, it is often used as a key building block for the construction of more complex organic molecular structures. Due to the synergistic effect of pyridine rings with formyl groups and methyl groups, it can trigger many classical organic reactions, such as nucleophilic addition, nucleophilic substitution, etc., helping synthetic chemists to create organic compounds with novel structures and specific functions, contributing to the development of organic synthetic chemistry. From this perspective, 2-formyl-5-methylpyridine is an indispensable and important substance in many fields such as medicine, materials, and organic synthesis, and has contributed to the promotion of scientific research and technological progress in various fields.
    What are the physical properties of 2-Formyl-5-methylpyridine?
    2-formyl-5-methylpyridine is one of the organic compounds. Its physical properties are quite important and are often concerned in the fields of chemical industry and scientific research.
    This compound is mostly liquid at room temperature and pressure. Looking at its color, it is usually almost colorless, but it may be slightly mixed with impurities, causing it to be slightly yellowish. Its appearance is clear and transparent, like clear water, but it contains unique chemical characteristics.
    Smell, 2-formyl-5-methylpyridine emits a special smell, which is not pungent and intolerable, but also has a distinct recognition. It seems to blend a light aroma with a slight irritating smell, and it seems to have a unique chemical charm hidden in it.
    When it comes to solubility, it is outstanding in organic solvents. Such as common ethanol, ether, chloroform, etc., can be fused with it, just like fish water, and easily form a uniform and stable solution. However, in water, the solubility is not good, and the two are like incompatible enemies, only slightly soluble, and it is difficult to achieve a uniform dispersion state.
    Its boiling point and melting point are also key physical parameters. The boiling point reaches a certain value under specific pressure conditions. This value makes the compound gradually change from liquid to gaseous when heated to the corresponding temperature. The melting point determines the critical temperature at which it changes from solid to liquid. These two parameters are of great significance for the separation, purification and selection of application scenarios of compounds.
    In terms of density, 2-formyl-5-methylpyridine is larger than water, and it is placed in water, such as stone sinking abyss, and slowly settles at the bottom. This property may become an important basis in the study of some separation processes or mixed systems.
    Overall, the physical properties of 2-formyl-5-methylpyridine establish its unique position in the field of chemistry, providing indispensable basic information for researchers to explore its chemical behavior and industrialists to plan production and application.
    What is the chemical synthesis method of 2-Formyl-5-methylpyridine?
    The synthesis of 2-formyl-5-methylpyridine is an important subject in organic synthetic chemistry. To obtain this compound, it can be achieved through several routes.
    One method can start from 5-methylpyridine-2-methanol. First, under these mild conditions, the hydroxyl group of 5-methylpyridine-2-methanol is oxidized to an aldehyde group to obtain 2-formyl-5-methylpyridine. This reaction has the advantages of good selectivity and mild conditions. However, the cost of the oxidizing agent is higher, and the cost factor may need to be considered when preparing on a large scale.
    The second method is to use 5-methyl-2-halogenated pyridine as the raw material. First, it is reacted with metal magnesium to make Grignard reagent, and then reacted with N, N-dimethylformamide (DMF). After this nucleophilic addition reaction and then hydrolysis step, the target product 2-formyl-5-methylpyridine can be obtained. Although the raw materials for this route are relatively easy to obtain, the preparation of Grignard's reagent requires harsh conditions of anhydrous and anoxic, and the operation process is more complicated, which requires high experimental technology.
    Another method uses 2,5-dimethylpyridine as the starting material. Using suitable selective oxidation reagents, such as a system of specific catalysts and oxygen combinations, the 2-position methyl is selectively oxidized to aldehyde groups, and 2-formyl-5-methylpyridine can also be obtained. This method has high atomic economy and conforms to the concept of green chemistry. However, the control of selective oxidation is quite difficult, and the reaction conditions need to be carefully regulated.
    In conclusion, various methods for synthesizing 2-formyl-5-methylpyridine have their own advantages and disadvantages. Experimenters should carefully choose the appropriate synthetic route according to their own conditions, such as raw material availability, cost considerations, experimental equipment and technology.
    2-Formyl-5-methylpyridine in what areas?
    2-formyl-5-methylpyridine, this is an organic compound. It has important applications in the field of pharmaceutical synthesis. It has a special structure, contains a pyridine ring with an aldehyde group and a methyl group, and is active in nature. It can be prepared through a series of chemical reactions to obtain a variety of drug intermediates. If you want to synthesize drugs for specific treatment of cardiovascular diseases, you can use 2-formyl-5-methylpyridine as a starting material, and use aldehyde groups to react with other compounds containing specific functional groups to construct the key structural fragments required for drugs, and then synthesize drug molecules with specific physiological activities.
    In the field of materials science, it also has its uses. Because the pyridine ring has a certain conjugate structure, it can participate in the construction of materials with special optoelectronic properties. Based on 2-formyl-5-methylpyridine, modified and polymerized, luminescent materials that can be applied to organic Light Emitting Diodes (OLEDs) can be prepared. Due to its special structure or unique luminescent properties, the luminous efficiency and color purity of OLED devices can be optimized.
    In the field of organic synthetic chemistry, as an important intermediate, it is often used to construct more complex heterocyclic compounds. Chemists can use the reactivity of their aldehyde groups and methyl groups to convert them into various new organic compounds through reactions such as condensation and substitution, providing rich structural types of compounds for the development of organic synthetic chemistry, promoting the progress of organic synthesis methodologies, and helping to develop more efficient and green organic synthesis routes.
    What is the market price of 2-Formyl-5-methylpyridine?
    I think what you are asking is about the market price of 2-formyl-5-methylpyridine. However, it is not easy to know its price. This is due to the fluctuation of prices between market changes, which is subject to many factors.
    First, the situation of supply and demand is very related. If there are many applicants for this product, but there are few suppliers, the price will increase; conversely, if the supply exceeds the demand, the price will be depressed. Second, the price of raw materials is also the key. The production of 2-formyl-5-methylpyridine depends on all kinds of raw materials. The price of raw materials moves, and the price of finished products also follows. Third, the difficulty of the production method and the simplicity of the process can affect the price. If the production method is complicated and the process cost is high, the price will also be high. Fourth, the competition in the market also affects the price. If there are many competitors in the same industry, the price may decline in order to compete for customers; if there are few competitors, the price may remain high.
    And in the market, the price varies from region to region. And with time migration, the price may rise or fall. Therefore, in order to know the exact price of 2-formyl-5-methylpyridine, when you visit the chemical raw material market in real time, consult various suppliers, or refer to professional chemical information platforms, you can get a near-real price.