2 Formyl 3 Fluoropyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Formyl-3-fluoropyridine

    Specifications

    HS Code

    695080

    Chemical Formula C6H4FNO
    Appearance Colorless to light yellow liquid
    Boiling Point 195 - 197 °C
    Density 1.218 g/cm³
    Flash Point 77.3 °C
    Solubility In Water Slightly soluble
    Purity Typically high purity available, e.g., 95%+
    Stability Stable under normal conditions

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    General Information
    Where to Buy 2-Formyl-3-fluoropyridine in China?
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    Frequently Asked Questions

    As a leading 2-Formyl-3-fluoropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-formyl-3-fluoropyridine?
    The main uses of 2-ethyl-3-pentene are important in many fields. In the field of organic synthesis, this compound can be called a key intermediate. Due to its unique carbon-carbon double bond structure, it can interact with many reagents through addition reaction, and then synthesize a wide variety of organic compounds. For example, by addition to hydrogen halides, halogenated hydrocarbons can be formed. Such halogenated hydrocarbons can be used to form carbon-carbon bonds, carbon-heteroatomic bonds, etc. in subsequent reactions, and are widely used in drug synthesis, material preparation, etc.
    In the field of materials science, 2-ethyl-3-pentene can be used as a monomer to participate in the polymerization reaction. Through appropriate polymerization methods, polymer materials with specific properties can be obtained. Its polymers may have good flexibility, mechanical properties, etc., showing potential application value in plastic products, rubber substitutes and other fields.
    In addition, in the fragrance industry, 2-ethyl-3-pentene is also useful. Due to its special chemical structure, it may have a unique odor. With proper preparation and treatment, it can become an integral part of the fragrance formula and add a unique aroma to the product.
    In some fine chemical production processes, 2-ethyl-3-pentene can be used to prepare special surfactants. Because of its molecular structure, there are both lipophilic alkyl moieties and reactive double-bond moieties, hydrophilic groups can be introduced through further chemical reactions to prepare surfactants with unique properties, which are used in fields such as emulsion polymerization and detergents. In short, 2-ethyl-3-pentene plays an important role in many fields such as organic synthesis, materials, fragrances, and fine chemicals due to its special structure, and has high application value.
    What are the physical properties of 2-formyl-3-fluoropyridine?
    The physical properties of 2-% methoxy-3-proparynyl are as follows:
    This compound has a specific chemical properties, and its methoxy group is composed of a methyl group, which is above the main group. However, the proparynyl group contains carbon trioxide, which gives this compound a special chemical activity.
    As far as physical properties are concerned, its melting boiling is affected by the molecular force. Due to the presence of a methoxy group in the molecule, the molecule has an even-even force, and the phase is non-toxic compounds. However, due to the non-large molecular weight of the whole group, the melting boiling is not high. And its solubility is high, and it can have a certain solubility in some dissolves such as alcohols and ethers, and can form molecular forces on the dissolves of molecules, such as molecules or even-even interactions.
    In terms of chemical properties, the carbon trioxide of propionyl groups has high reaction activity. It can generate addition reactions, such as additives such as chlorine, chlorine, etc. Due to the high density of chlorine in the trioxide, it is susceptible to attack. For example, when bromine water is reversed, carbon trioxide can be gradually added to bromine atoms, causing bromine water to fade. In addition, oxidation reactions can also be performed. Under the action of sulfur, carbon trioxide can be oxidized and cracked to form oxidized compounds. The methoxy phase is fixed, but under specific conditions such as acid, it may also generate reactions, such as demethylation, substitution reactions, etc.

    Therefore, the 2-methoxy-3-propane gene itself is unique, and it has specific physical properties. It has a certain value in the field of synthesis and other fields.
    What are the chemical properties of 2-formyl-3-fluoropyridine?
    The chemical properties of 2-% methyl-3-proparynyl are as follows:
    This group has unique reactivity. From its structural perspective, methyl is a common alkyl group with relatively stable properties, which can enhance the lipid solubility of molecules and affect the physical properties of molecules such as boiling point and solubility. Because it is a saturated alkyl group, it is usually not easy to undergo addition reactions. However, free radical substitution reactions can occur under specific conditions, such as high temperature, light or when there is a suitable catalyst. Like under chlorine light conditions, hydrogen atoms on methyl groups can be replaced by chlorine atoms.
    And proparynyl groups contain carbon-carbon three bonds, which are highly unsaturated bonds, giving the group active chemical properties. The carbon-carbon triple bond has a large degree of unsaturation, high electron cloud density, and is vulnerable to attack by electrophilic reagents, resulting in electrophilic addition reactions. For example, it can be added with hydrogen halide to form halogenated olefins. If the amount of hydrogen halide is sufficient, it can be further added to form halogenated alkanes. It can also undergo an addition reaction with bromine water to fade bromine water, which is a commonly used method for identifying carbon-carbon triple bonds.
    At the same time, the carbon-carbon triple bond of proparynyl can also undergo a hydration reaction. Under the action of catalysts such as mercury salts, it is added with water to form carbonyl compounds. In organic synthesis, proparynyl is often used as an important synthesizer to construct complex organic molecular structures. Due to its unsaturation, it can also participate in various cyclization reactions, such as Diels-Alder reaction variants with suitable dienes, to form cyclic compounds and expand the structural diversity of molecules. Under metal catalysis, propyne groups can also participate in coupling reactions and combine with other organohalides or organometallic reagents to achieve the construction of carbon-carbon bonds, which can be used to synthesize organic compounds with specific structures and functions.
    What are the synthesis methods of 2-formyl-3-fluoropyridine?
    To prepare 2-methyl-3-methoxypyridine, there are various methods.
    First, start with a suitable pyridine derivative, and select an appropriate methylation reagent, such as iodomethane, under suitable reaction conditions, introduce methyl at a specific position on the pyridine ring. After that, the step of methoxylation can be carried out. Nucleophilic substitution reaction can be used to react with halogen-containing pyridine derivatives with sodium alcohol or sodium phenol, and the halogen atom is replaced by methoxy to obtain the target product. This process requires attention to the control of reaction conditions, such as temperature, solvent and catalyst selection, due to different conditions or product yield and purity are different. < Br >
    Second, it can be achieved by the strategy of constructing pyridine rings. For example, using nitrogen-containing and carbon-containing raw materials, through a series of reactions such as condensation and cyclization to form pyridine rings. During the cyclization process, the reaction path is cleverly designed to introduce methyl and methoxyl groups at the desired position. This approach requires a deep understanding of the reaction mechanism, and the selection of raw materials and the arrangement of reaction steps are crucial. For example, using specific amines and carbonyl compounds as starting materials, through multi-step reactions, pyridine rings are gradually constructed and corresponding substituents are introduced.
    Third, catalytic coupling can also be used. The suitable halogenated pyridine derivative is selected, and the coupling reaction occurs with the nucleophilic reagent containing methyl and methoxy groups under the action of the catalyst. Among them, the activity and selectivity of the catalyst have a great impact on the success or failure of the reaction. Commonly used catalysts such as palladium catalysts can optimize the reaction effect and improve the production efficiency of the target product by modulating the ligand and reaction conditions.
    All these methods have advantages and disadvantages. In the actual synthesis, when considering the availability of raw materials, the ease of control of reaction conditions and production costs, the optimal method is selected to prepare 2-methyl-3-methoxy pyridine.
    What is the price range of 2-formyl-3-fluoropyridine on the market?
    Today, there are 2-methyl-3-pentene, and the price is determined in the market. The range of price is difficult to determine, and it depends on many reasons.
    The price of raw materials is its foundation. The raw material of 2-methyl-3-pentene, if it is easy to obtain and widely produced, is low in price; if the raw material is rare, difficult to harvest, and difficult to make, the price must be high. And the price of raw materials also changes with the market. The increase or decrease in the output of the origin and the change in supply and demand can cause fluctuations in the price of raw materials, and then the price of 2-methyl-3-pentene.
    The method of preparation is related to cost. If the preparation method is simple and efficient, with less energy consumption, less impurities, and the equipment and reagents used are normal, the cost will drop and the price will follow; if the preparation requires exquisite equipment, harsh conditions, and difficult steps, the price will rise. As the new technology comes out, if the preparation process can be optimized, the price may also be changed.
    Market supply and demand, the cardinal of the price. If there are many people in the market seeking 2-methyl-3-pentene, and there are few suppliers, the demand will exceed the supply, and the price will rise; on the contrary, if the supply exceeds the demand, the merchant wants to sell its goods, and must reduce its price to compete for the market. And the demand of the market also changes with the rise and fall of various industries. For example, the increase or decrease of the demand for it in the chemical industry, medicine and other industries can make the price rise or fall.
    Quality specifications are related to the price. High-quality and strict specifications of 2-methyl-3-pentene, the testing is harsh, and the production is fine, and the price must be higher than that of regular products. Different users have different requirements for quality, and the price varies accordingly.
    Transportation and storage also cost resources. 2-methyl-3-pentene may require special storage equipment, specific temperature and humidity, and transportation must also prevent its explosion and deterioration. These costs are all included in the cost, resulting in different prices. Long-distance transportation is risky and expensive, and the price may be higher.
    From this perspective, the price of 2-methyl-3-pentene in the market can range from a few dollars per gram to tens of dollars per gram, or even worse. Its price is variable, depending on the above reasons, and it should be observed from time to time.