2 Fluoro 6 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Fluoro-6-(trifluoromethyl)pyridine

    Specifications

    HS Code

    893313

    Chemical Formula C6H3F4N
    Molar Mass 165.09 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 112 - 114 °C
    Density 1.354 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Flash Point 23 °C

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    General Information
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    Frequently Asked Questions

    As a leading 2-Fluoro-6-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-fluoro-6- (trifluoromethyl) pyridine?
    2-% -6- (trimethylmethyl) pyridine, its main uses are various. This substance is often used as a key raw material for the synthesis of drugs in the field of medicine. The structure of Geinpyridine has unique chemical properties, and the introduction of specific substituents in this compound can change the activity and selectivity of the compound. Taking some antibacterial drugs as an example, with intermediates containing 2-% -6- (trimethylmethyl) pyridine structure, drugs with high inhibitory effect on specific bacteria can be prepared to treat related diseases.
    In the field of materials science, it also has important applications. Can be used as a basic component for the preparation of special functional materials. For example, in the synthesis of organic optoelectronic materials, incorporating them into the molecular structure can regulate the electron transport properties and optical properties of the materials. Because the arrangement of atoms and electron cloud distribution in the structure can affect the absorption, emission and charge migration of the material to light, it is helpful to develop new optoelectronic devices such as Light Emitting Diode and solar cells to improve their performance and efficiency.
    In the field of pesticides, 2-% -6- (trimethyl) pyridine is also an important starting material for the synthesis of pesticides. After chemical modification, compounds with insecticidal, bactericidal or herbicidal activities can be obtained. Because the structure has specific affinity with some target checking points in the organism, it can interfere with the physiological and metabolic process of pests or pathogens, so as to achieve the purpose of controlling pests, protecting crops, and ensuring the harvest of agricultural production.
    What are the physical properties of 2-fluoro-6- (trifluoromethyl) pyridine?
    2-% hydroxyl-6- (trihydroxymethyl) pyridine, this material has a variety of characteristics. It is an organic compound, under normal temperature and pressure, mostly in a stable state. Looking at its appearance, it is usually white to light yellow crystalline powder, fine and uniform, slightly shiny.
    When it comes to solubility, it shows good solubility in water, just like salt in water, uniform and smooth. This characteristic is derived from the hydroxyl groups contained in the molecular structure, which can form hydrogen bonds with water molecules, so that the two can be fused seamlessly. In common organic solvents, such as ethanol and methanol, it also has good solubility, and can be mixed with organic solvents, regardless of each other.
    Besides, its melting point, after rigorous determination, is roughly in a specific temperature range. This temperature is the critical point of its transition from solid to liquid, just like the node where ice melts into water, and is crucial for material identification and purity determination. The stability of its melting point is also one of the inherent properties of a substance, which can be used as an important basis for measuring its quality.
    In terms of chemical activity, its molecular structure of hydroxyl groups and pyridine rings gives it unique reactivity. Hydroxyl groups can participate in many common chemical reactions, such as esterification reactions, which are similar to the combination of acids and alcohols to form esters and water. Under appropriate conditions, hydroxyl groups are oxidized to different functional groups such as aldehyde groups and carboxyl groups. Due to its unique electron cloud distribution, pyridine ring can undergo nucleophilic substitution, electrophilic substitution and other reactions with a variety of reagents, showing rich chemical changes, providing many possibilities for the field of organic synthesis.
    What are the synthesis methods of 2-fluoro-6- (trifluoromethyl) pyridine?
    To prepare 2-hydrocarbon-6- (trihydrocarbon methyl) pyridine, there are three methods.
    First, using pyridine as the base, through halogenation, a halogen atom is introduced into the specific check point of the pyridine ring, and then with the reagent containing trihydrocarbon methyl, according to the reaction mechanism of nucleophilic substitution, the halogen atom is replaced by trihydrocarbon methyl, and the target product can be obtained. This process requires selecting a suitable halogen agent, such as halogen elemental substance or hydrogen halide, and controlling the temperature, time and ratio of the reactants to achieve the best reaction effect and improve the yield and purity of the product. < Br >
    Second, a pyridine ring is formed by cyclization of a benzene ring compound containing an appropriate substituent and a nitrogen-containing reagent. First, under suitable reaction conditions, the benzene ring derivative undergoes a series of reactions such as condensation and cyclization with the nitrogen source to construct the structure of the pyridine ring, and then for the specific position of the pyridine ring, a hydrocarbyl reaction is carried out to introduce trihydrocarbon methyl. The key to this path lies in the precise regulation of the cyclization reaction conditions and the selectivity of the subsequent hydrocarbyl reaction. An efficient catalyst and a suitable reaction solvent are required.
    Third, the existing pyridine derivatives are used through the method of functional group transformation. If the pyridine derivative has convertible functional groups, such as carboxyl groups, hydroxyl groups, etc., it can be gradually converted into the target trihydrocarbon methyl group through a series of chemical reactions. For example, the carboxyl group can be reduced to alcohol first, then halogenated, and reacted with trihydrocarbon methyl reagents to achieve the conversion of functional groups and the synthesis of the target product. This approach requires familiarity with the reaction conditions and sequence of various functional group conversions to ensure the smooth progress of the reaction.
    What are the precautions for storing and transporting 2-fluoro-6- (trifluoromethyl) pyridine?
    2-% Jiang-6- (triethylmethyl) pyridine in storage and transportation, need to pay attention to many matters. This substance has specific chemical properties, and when stored, the first environmental conditions. It should be placed in a cool, dry and well-ventilated place, due to moisture and high temperature or cause deterioration. Moisture can easily cause reactions such as hydrolysis, which affect its chemical structure and purity; high temperature may change the activity of molecules, and even trigger decomposition reactions.
    Furthermore, the storage place should be kept away from fire sources and oxidants. Pyridine compounds are flammable, and can be burned in case of open flames and hot topics. If they come into contact with oxidants, they are more likely to cause violent reactions, such as explosions and other serious consequences.
    When transporting, the packaging must be stable. Suitable packaging materials need to be selected to ensure that they are not damaged or leaked due to vibration or collision during transportation. And transportation vehicles should also meet safety standards and have fire and explosion-proof facilities.
    At the same time, transportation personnel must be professionally trained to be familiar with the characteristics of this chemical and emergency treatment methods. In the event of a leak, they can respond quickly and correctly. For example, if there is a leak, the surrounding population should be evacuated immediately, and fire should be strictly prohibited. At the same time, according to the leakage volume and site conditions, corresponding treatment measures should be taken, such as adsorption with inert materials such as sand, or neutralization with suitable chemical reagents. In this way, the safety of 2-% Jiang-6- (triethyl) pyridine during storage and transportation can be ensured, accidents can be avoided, and personnel and the environment can be protected.
    What is the market outlook for 2-fluoro-6- (trifluoromethyl) pyridine?
    Today there is dihydroxyhexa (trihydroxymethyl) heptyl, what is the situation in the city? Let me tell you in detail.
    This dihydroxyhexa (trihydroxymethyl) heptyl is a quality in the chemical industry, and its situation in the city is related to all kinds of things. In today's world, the chemical industry is booming, and it is also prosperous in the pursuit of all kinds of quality.
    Dihydroxyhexa (trihydroxymethyl) heptyl is useful in many fields. In the field of medical and chemical technology, it may be used to make good medicines. Today's people are very important in health, and the need for medicine is always prosperous. If this quality is beneficial to pharmaceuticals, the market may have a lot of needs. Doctors seek good medicines to cure diseases, and pharmaceuticals seek good materials to make medicines. If dihydroxyhexa (trihydroxymethyl) heptyl has good capabilities, it is important for pharmaceuticals, and the market scene should be considerable.
    In the field of material science, the materials of chemical industry are changing with each passing day. This quality may be able to participate in the production of new materials. The emergence of new materials brings new opportunities to various industries. If the industry is built, seek strong and beautiful materials; if the equipment is made, seek light and strong materials. If dihydroxyhexa (trihydroxymethyl) heptyl can help to make such good materials, its market road is also wide. Workers hope for excellent materials and thrive in business. If dihydroxyhexane (trihydroxymethyl) heptyl responds to its requests, the scene of the city will not be bleak.
    However, the scene of the city is not only about use, but also involves production and supply. If the amount of production is small and it is difficult to meet the needs of the public, the expansion of the city will be limited. On the contrary, if the production capacity is sufficient, and the quality is high and the price is suitable, it will definitely attract merchants to compete and customers to favor. Businesspeople seek profit, and customers seek use, and both can be obtained. The scene of the city is prosperous.
    Also, the scene of the city changes constantly, due to the progress of technology and the change of regulations. The quality of technological progress may be excellent, and the production may be increased; the regulations and changes may be in practice, and the city may be regulated. The city of dihydroxyhexa (trihydroxymethyl) heptyl has also changed with this. Therefore, looking at the scenery of its city, we need to look at it comprehensively, in order to get a full picture of it and know its trend of rise and fall.