2 Fluoro 5 Hydroxymethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Fluoro-5-(hydroxymethyl)pyridine

    Specifications

    HS Code

    874500

    Chemical Formula C6H6FNO
    Molar Mass 127.12 g/mol
    Appearance Solid (predicted)
    Solubility In Water Unknown
    Logp Estimated value
    Pka Unknown

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    General Information
    Where to Buy 2-Fluoro-5-(hydroxymethyl)pyridine in China?
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    Frequently Asked Questions

    As a leading 2-Fluoro-5-(hydroxymethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-fluoro-5- (hydroxymethyl) pyridine?
    2-% pentyl-5- (methoxy) alkyne is an important organic compound with a wide range of uses and plays a key role in many fields.
    In the field of organic synthesis, this compound can be called an extremely important synthetic intermediate. Due to its unique structure, the presence of alkynyl and methoxy groups gives it special reactivity. Chemists can use carefully designed chemical reactions to take advantage of the properties of its alkynyl groups that are prone to nucleophilic addition, cyclization and other reactions to ingeniously construct various complex organic molecules with specific structures and functions. For example, the construction of polycyclic aromatic hydrocarbons, heterocyclic compounds, etc., provides key structural modules for research in pharmaceutical chemistry, materials science and other related fields, and helps to develop new drug molecules, high-performance materials, etc.
    In the field of drug development, 2-% pentyl-5- (methoxy) alkyne shows great potential. Studies have found that compounds containing similar alkynyl and methoxy structures have good affinity and activity to some specific biological targets. By in-depth study of the interaction mechanism between this compound and its derivatives and biological macromolecules, it is expected to develop new therapeutic drugs for treating major diseases such as cancer and cardiovascular diseases, bringing new hope to human health.
    In the field of materials science, it also has important applications. Due to its special structure, materials can be endowed with unique electrical, optical or mechanical properties. For example, introducing it into the structure of polymer materials may improve the conductivity and fluorescence properties of materials, resulting in the preparation of new optoelectronic materials, which can be used in organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices to promote the progress and development of materials science.
    In summary, 2-% pentyl-5- (methoxy) alkyne, with its unique structure and reactivity, plays an important role in organic synthesis, drug development and materials science, providing strong support for innovation and development in various fields.
    What are the synthesis methods of 2-fluoro-5- (hydroxymethyl) pyridine?
    2-% E6% B0% 9F-5- (%E7%BE%9F%E7%94%B2%E5%9F%BA) % E5% 90% A1% E5% 95% B6, also known as 2-pentene-5-ketone, this substance can be combined by a variety of wonderful methods, the following will be described in detail.
    First, beta-ketoate is used as the starting point, and this substance can be formed by the method of Claisen condensation. First, take an appropriate amount of beta-ketoate, such as ethyl acetoacetate, and place it in the environment of alkaline catalysts such as sodium alcohol. At a suitable temperature, the esters condense with each other to obtain beta-ketoate derivatives. Then it is hydrolyzed under acidic conditions, and then thermally decarboxylated to obtain 2-pentene-5-one. This process requires attention to the control of reaction temperature and catalyst dosage in order to obtain higher yields.
    Second, the method of hydroxyaldehyde condensation can also be used. Using acetone and propionaldehyde as raw materials, under dilute alkali catalysis, hydroxyaldehyde condensation reaction occurs first to obtain β-hydroxyaldehyde. Then it is heated and dehydrated to form 2-pentene-5-one. The key to this reaction is to control the concentration of the base and the reaction time. If the concentration is too high or the time is too long, it is easy to cause side reactions and affect the purity of the product.
    Third, it can also be prepared by Michael addition reaction. For example, using α, β-unsaturated ketones and active methylene compounds as raw materials, under the action of basic catalysts, the hydrogen of active methylene compounds and the β-carbon addition of α, β-unsaturated ketones can obtain Michael addition products. After appropriate treatment, such as hydrolysis, decarboxylation and other steps, the target product can also be obtained. In this process, it is very important to regulate the activity of the raw materials and the reaction conditions.
    The above methods have their own advantages and disadvantages, and the best synthesis effect should be selected according to the actual situation, such as the availability of raw materials, cost, and product purity requirements.
    What are the physical properties of 2-fluoro-5- (hydroxymethyl) pyridine?
    2-% hydrocarbon-5- (hydroxymethyl) pentactyl is a very special substance with many unique physical properties.
    Its appearance is often a colorless and transparent liquid, and its texture is relatively viscous, just like the dew rolling on the lotus leaf in the morning, and it glows warm and shiny under the light. This substance has good solubility and can be miscible with water in any ratio. It is as natural and smooth as salt into water, and can also be miscible with many organic solvents, such as ethanol, acetone, etc., as if water is emulsion.
    The boiling point of 2-% hydrocarbon-5- (hydroxymethyl) pentane is quite high, and it needs a relatively high temperature to boil under normal pressure, just like real gold can be produced by hard work. This characteristic makes it relatively stable in higher temperature environments. Its melting point is relatively low, and it is similar to ice and snow melted at the beginning of spring, and it is easy to change from solid to liquid.
    Furthermore, the density of this substance is slightly higher than that of water. If it is slowly poured into the water, it will sink like a stone sinking to the bottom. And it has a certain volatility. In an open environment, it will gradually evaporate like blue smoke, but the evaporation rate is slower than that of some common volatile substances.
    In addition, 2% hydrocarbon-5- (hydroxymethyl) pentane also has good hygroscopicity, just like a dry sponge placed in humid air, it is easy to absorb moisture in the air, thereby changing its concentration and state. The surface tension of this substance is also unique, which can make the surface of the liquid resemble an elastic film, which has a significant impact on its behavior at the interface.
    All kinds of physical properties make 2% hydrocarbon-5- (hydroxymethyl) pentane have important applications in many fields, whether it is chemical production or scientific research.
    What are the precautions for storing and transporting 2-fluoro-5- (hydroxymethyl) pyridine?
    2-% hydrocarbon-5- (hydroxymethyl) valeraldehyde needs to be paid attention to during storage and transportation.
    When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, away from fires and heat sources. Because the substance may be flammable to a certain extent, if it encounters an open flame or hot topic, it may cause fire and other risks. The temperature and humidity of the warehouse should also be strictly controlled to ensure its chemical stability and prevent deterioration due to abnormal temperature and humidity.
    Furthermore, when storing, it should be noted that it should be stored separately from other chemicals. Due to its special chemical structure, some substances come into contact with it or react chemically, resulting in danger. For example, strong oxidizing agents or severe oxidation reactions with 2-hydrocarbon-5- (hydroxymethyl) valeraldehyde should be avoided.
    When transporting, the packaging must be tight. Select appropriate packaging materials to ensure that no leakage occurs during transportation. Leakage will not only cause material loss, but also cause pollution to the environment and may also endanger the health of transporters.
    Transportation vehicles must also meet safety requirements and be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. During driving, drivers should abide by traffic rules, drive at a steady speed, and avoid violent actions such as sudden braking and sharp turns to prevent leakage due to damage to packaging. At the same time, transportation route planning should also be cautious, avoiding sensitive areas such as densely populated areas and water sources to reduce the risk of accidents. In short, whether storing or transporting 2-hydrocarbon-5- (hydroxymethyl) valanal, it must be carefully considered and operated in strict accordance with regulations to ensure the safety of personnel, the environment and property.
    What is the market outlook for 2-fluoro-5- (hydroxymethyl) pyridine?
    2-% Ming-5- (hydroxymethyl) pyridine, the market prospect of this product is related to many aspects.
    Looking at its characteristics, 2-% Ming-5- (hydroxymethyl) pyridine has unique chemical structures and properties, and has important applications in the chemical and pharmaceutical fields. In the chemical industry, it can be used as a key intermediate for the synthesis of special materials. Its structure gives the product unique properties, such as higher stability and special reactivity, which makes it highly attractive in the development of new materials. It is expected to open up a wide range of fields in the field of high-end material manufacturing.
    In the field of medicine, its potential cannot be underestimated. It can be used as a raw material for the synthesis of specific drugs, or participate in the modification of drug molecules to improve the pharmacokinetic properties of drugs, such as improving solubility and enhancing bioavailability. In view of the continuous growth of demand for innovative drugs in the pharmaceutical industry, 2-% Ming-5- (hydroxymethyl) pyridine is expected to rise steadily in the future as a key component of potential drug synthesis.
    Re-examine the market environment. With technological progress and industrial upgrading, the requirements for the quality and purity of fine chemicals are becoming increasingly stringent. If the production process of 2-% Ming-5- (hydroxymethyl) pyridine can be continuously optimized, product quality and yield can be improved, and market demand can be met, it will be able to gain an advantage in the competition. And the scale of the global chemical and pharmaceutical industries continues to expand, providing them with broad market space. However, it should also be noted that the market competition is also becoming more intense, and the emergence of new entrants or new technologies may pose challenges to its market share.
    In summary, the market prospect of 2-% Ming-5- (hydroxymethyl) pyridine is promising, but many challenges need to be addressed. If we can seize the opportunity and improve our technology, we are expected to achieve great results in the market.