2 Fluoro 3 Pyridinemethanaminedihydrochloride
pyridine pyrrole pyrazine piperidine piperazine

2-fluoro-3-pyridinemethanaminedihydrochloride

    Specifications

    HS Code

    729725

    Chemical Formula C6H9Cl2FN2O
    Molecular Weight 215.05
    Appearance Solid (likely white or off - white powder)
    Solubility Soluble in polar solvents like water and some alcohols
    Pka Related to the basicity of the amine group, values would depend on solvent and conditions
    Hazard Class May be harmful if swallowed, inhaled or in contact with skin; exact classification needs further toxicological data

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 2-fluoro-3-pyridinemethanaminedihydrochloride?
    The chemical structure of 2-fluoro-3-pyridylmethylamine dihydrochloride is as follows. The pyridine ring is a six-membered nitrogen-containing heterocyclic ring with unique aromatic properties. In the second position of the pyridine ring, there are fluorine atoms connected, and the fluorine atoms have strong electronegativity, which has a great influence on the electron cloud distribution and chemical properties of the pyridine ring. In the third position of the pyridine ring, there is a methylamine group connected, which is formed by the connection of a methyl group and an amino group. The amino group has a lone pair of electrons and is basic. It can react with acids to form salts, which is the reason why it interacts with hydrochloric acid to form dihydrochloride.
    In this compound, the π electron cloud conjugated system of the pyridine ring interacts with the electron-sucking induction effect of the fluorine atom, the electron-inducing effect and the conjugation effect of the methylamine group, resulting in rich chemical properties. The form of dihydrochloride is due to the fact that the lone pair electrons on the nitrogen atom of the amino group can accept two protons, and form a salt with hydrochloric acid, which makes the compound more stable under specific conditions, and the physical properties such as solubility also change. This chemical structure makes it potentially useful in organic synthesis, pharmaceutical chemistry and other fields. Due to the characteristics of each group in the structure, it can be used as a reaction check point or a key structure for interaction with biological targets.
    What are the physical properties of 2-fluoro-3-pyridinemethanaminedihydrochloride?
    2-Fluoro-3-pyridylmethylamine dihydrochloride is an organic compound. Its physical properties are very important and relevant to its many applications.
    First appearance, this substance is usually in the state of white to off-white crystalline powder, which is easy to observe and process, and is of significance in laboratory operations and industrial production. From the perspective, the color is pure and the crystallization is regular, reflecting its high purity.
    Second description Solubility, 2-fluoro-3-pyridylmethylamine dihydrochloride is easily soluble in water. Water is a common solvent, and this solubility allows the reaction and analysis of the compound in aqueous solution systems to be carried out smoothly. When it is dissolved in water, the degree of ionization is higher. Because it is dihydrochloride, chloride ions dissociate, causing the compound to be uniformly dispersed in water in an ionic state, increasing its reactivity and system stability.
    Furthermore, the melting point is also a key physical property. However, the exact melting point varies slightly due to factors such as preparation method and purity, and is roughly in a specific temperature range. The determination of the melting point can determine its purity. Those with high purity have a narrow melting point range and approach the theoretical value; impure substances have a lower melting point and a wider melting range.
    In addition, the density of the compound is also one of its characteristics. Although the specific value varies depending on the measurement conditions, its density is very important to determine the relationship between mass and volume in a specific system, and has practical value in the calculation of material ratio and reactor volume in chemical production.
    In summary, the physical properties of 2-fluoro-3-pyridylmethylamine dihydrochloride, such as white crystalline powder appearance, good water solubility, specific melting point and density, lay the foundation for its application in organic synthesis, drug development and other fields, and are indispensable in related research and production practice.
    What are the main uses of 2-fluoro-3-pyridinemethanaminedihydrochloride?
    2-Fluoro-3-pyridinemethanamine dihydrochloride is an organic compound with a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. Due to its unique activity in many drug molecules, fluoropyridine-containing structures can participate in drug synthesis and help create novel drugs to treat diseases.
    In the process of drug development, scientists can develop drugs with higher efficacy and lower side effects by modifying and modifying their structures. For example, drug molecules can be precisely designed for specific disease targets, improving the ability of drugs to bind to targets and enhancing therapeutic effects.
    In the field of materials science, 2-fluoro-3-pyridinemethanamine dihydrochloride may also have applications. Its special chemical structure may endow materials with unique properties, such as participating in the preparation of materials with special optical and electrical properties, and playing a role in optoelectronic devices, sensors, etc.
    Furthermore, in the field of organic synthesis, it can be used as an important building block to participate in the construction of complex organic molecules. Chemists can use its activity check point to build diverse organic structures through various chemical reactions, expand the types and properties of organic compounds, and contribute to the development of organic synthesis chemistry. In short, 2-fluoro-3-pyridinemethanamine dihydrochloride has important potential application value in many fields.
    What are 2-fluoro-3-pyridinemethanaminedihydrochloride synthesis methods?
    The synthesis of 2-fluoro-3-pyridylmethylamine dihydrochloride is a key issue in organic synthetic chemistry. The synthesis route depends on the various reaction mechanisms and techniques of organic chemistry.
    In the past, pyridine was often used as the starting material to synthesize this compound. The specific structure of pyridine gives it unique reactivity. First, a halogenation reaction can be carried out at a specific position of pyridine. In this case, fluorine atoms are introduced at the 2-position. This halogenation reaction requires careful selection of suitable halogenating reagents and reaction conditions. Such as the selection of a specific fluorine-containing reagent, under the presence of a suitable temperature and catalyst, the fluorine atom precisely replaces the hydrogen atom at the 2-position of pyridine.
    When the preparation of 2-fluoropyridine is completed, continue to use it as a substrate to introduce methylamine groups at the 3-position. This process is often achieved by nucleophilic substitution reaction. Select a suitable methylamination reagent, under the catalysis of a suitable base, to promote the substitution of methylamine groups with 3-position halogen atoms or other leaving groups, thereby generating 2-fluoro-3-pyridine methylamine.
    Finally, the obtained 2-fluoro-3-pyridylmethylamine is converted into dihydrochloride. This is achieved by a salt-forming reaction with hydrochloric acid. The amount of hydrochloric acid and the reaction conditions are controlled to fully protonate 2-fluoro-3-pyridylmethylamine to form a stable bis hydrochloride. The whole process of
    synthesis requires careful regulation of each step of the reaction, precise control of reaction temperature, time, proportion of reactants and many other factors, and various separation and purification methods, such as column chromatography, recrystallization, etc. are required to obtain high-purity 2-fluoro-3-pyridylamine dihydrochloride products. In this way, the target product can be successfully synthesized.
    What is the market outlook for 2-fluoro-3-pyridinemethanaminedihydrochloride?
    In today's world, chemical substances are widely used in various fields. 2-Fluoro-3-pyridylmethylamine dihydrochloride is also one of the chemicals, and its market prospect is quite promising.
    From the perspective of the field of medicine, this compound has unique structures and characteristics, or it has made extraordinary contributions to the creation of new drugs. Today, pharmaceutical research and development is constantly improving, looking for drugs with better curative effects and fewer side effects. 2-Fluoro-3-pyridylmethylamine dihydrochloride, because of its chemical activity, may be a key raw material for the development of new drugs, and has emerged in the creation of anti-cancer, antiviral and other drugs. Therefore, the demand for it in the pharmaceutical industry is expected to grow.
    In the field of electronic materials, there is also a need for special chemicals. The electrical properties of 2-fluoro-3-pyridylmethylamine dihydrochloride may make it applicable in the manufacture of some electronic components. With the upgrading of electronic products, the demand for new materials is endless. If this compound can show its advantages in the field of electronic materials, its market share will definitely expand.
    Furthermore, scientific research and exploration are endless. Many scientific research projects require various chemical reagents as the basis for research. 2-Fluoro-3-pyridylmethylamine dihydrochloride is commonly used in scientific research experiments, and the procurement of scientific research institutions is also one of the sources of market demand. Its market supply should also change with the rise of scientific research.
    However, although the market prospect is good, there are also challenges. Synthesizing this compound may have complicated processes, and cost control is crucial. If the synthesis path can be optimized and the cost reduced, it will be able to compete in the market and take the lead. And environmental protection regulations are becoming increasingly stringent, and environmental protection considerations in the production process cannot be ignored.
    In summary, 2-fluoro-3-pyridylmethylamine dihydrochloride has potential opportunities in the fields of medicine, electronic materials, scientific research, etc. However, if you want to expand the market, process optimization and environmental compliance, you must pay attention.