2-(Ethylsulphonyl)imidazo[1,2-a]pyridine-3-sulphonamide

2-%28Ethylsulphonyl%29imidazo%5B1%2C2-a%5Dpyridine-3-sulphonamide, that is, 2 - (ethylsulfonyl) imidazolo [1,2 - a] pyridine-3 - sulfonamide, this compound has a very important use in the field of medicinal chemistry.
One of them is often used as a key intermediate in the process of drug development. Because of its unique chemical structure, it can be cleverly linked with other functional groups through a series of chemical reactions to construct compounds with more complex structures and specific biological activities. For example, many new antibacterial and antiviral drugs have been created as starting materials. Through structural modification and modification, new compounds can precisely act on specific targets of pathogens, enhance drug efficacy, and reduce damage to normal human cells.
Second, in pharmacological research, it can be used as a tool compound to help researchers delve deeper into the molecular mechanism of specific physiological and pathological processes in organisms. For example, by studying the interaction between the compound and specific proteins or enzymes, the regulatory mechanism of related signaling pathways can be clarified, providing key clues for elucidating the root causes of disease development, and then laying a theoretical foundation for the design of new therapeutic strategies.
Third, in high-throughput drug screening, it also has important value as a lead compound. Researchers can design and synthesize a large number of structural analogs according to their structural characteristics, build a compound library, and then use high-throughput screening technology to quickly filter out compounds with high affinity and activity for specific disease targets, which greatly accelerates the process of new drug development and improves research and development efficiency. In short, 2 - (ethylsulfonyl) imidazolo [1,2 - a] pyridine-3 - sulfonamide is of great significance in the field of modern drug development and pharmacology research, and promotes the continuous development of pharmaceutical science to new heights.

2-%28Ethylsulphonyl%29imidazo%5B1%2C2-a%5Dpyridine-3-sulphonamide, it is an organic compound. Its chemical properties are interesting and important for research in many fields.
This compound contains specific functional groups, ethylsulfonyl is connected to the pyridine-imidazole heterocyclic structure, and there are sulfonamide groups. The presence of ethylsulfonyl gives it a certain hydrophilicity and chemical activity. Because its sulfur atom has lone pairs of electrons, it can participate in a variety of chemical reactions, such as nucleophilic substitution reactions, and can interact with electrophilic reagents to form new chemical bonds.
Pyridine-imidazole heterocyclic structure adds unique stability and electronic properties to this compound. The presence of nitrogen atoms in the heterocyclic ring makes the electron cloud unevenly distributed, resulting in a certain polarity of the ring, which in turn affects its physical and chemical properties. This heterocyclic part can also participate in π-π stacking and plays an important role in the interaction between crystal structure and molecules. The sulfonamide group
gives the compound potential biological activity. In the field of medicinal chemistry, sulfonamides often have biological activities such as antibacterial and anti-inflammatory. The nitrogen and oxygen atoms in this group can interact with targets in organisms to form hydrogen bonds and other interactions to exert their biological effects.
Furthermore, the acidity and alkalinity of 2-%28Ethylsulphonyl%29imidazo%5B1%2C2-a%5Dpyridine-3-sulphonamide are also worthy of attention. The hydrogen atom on the nitrogen atom in the sulfonamide group has a certain acidity and can undergo deprotonation reaction under appropriate conditions, while the nitrogen atom on the pyridine ring has a certain alkalinity and can accept protons. This acid-base characteristic affects its existence form and chemical reactivity under different pH environments.
In short, 2-%28Ethylsulphonyl%29imidazo%5B1%2C2-a%5Dpyridine-3-sulphonamide has broad application prospects in organic synthesis, drug development and other fields due to its unique functional groups and structures.

To prepare 2 - (ethylsulfonyl) imidazolo [1,2 - a] pyridine-3 - sulfonamide, the method is as follows:
First take imidazolo [1,2 - a] pyridine as the starting material, and introduce ethylsulfonyl at its 2 positions with appropriate reagents and conditions. Alternatively, ethylsulfonyl halide, such as ethylsulfonyl chloride, can react with imidazolo [1,2 - a] pyridine in the presence of a base. For bases, such as potassium carbonate, triethylamine, etc., in suitable solvents, such as dichloromethane, N, N - dimethylformamide, and stir the reaction under temperature control. In this step, the intermediate of 2 - (ethylsulfonyl) imidazolo [1,2 - a] pyridine can be obtained.
Next, the intermediate is sulfonamated. React with an appropriate sulfonating agent, such as chlorosulfonic acid, to obtain the corresponding sulfonic acid chlorine intermediate. Subsequently, react with ammonia or suitable derivatives of ammonia, such as ammonia, methylamine, etc., to obtain 2 - (ethylsulfonyl) imidazolo [1,2 - a] pyridine-3 - sulfonamide. This step requires attention to the control of reaction conditions, such as temperature and the ratio of reactants, to prevent side reactions. < Br >
Or another method can be found, using pyridine as the starting material, through multi-step reaction, the structure of imidazolo [1,2-a] pyridine is gradually constructed, and ethylsulfonyl and sulfonamide groups are introduced at the same time. However, this process may be more complicated, and the reaction steps need to be carefully planned, and the yield and selectivity of each step need to be carefully considered. In the reaction, the reagents and solvents used should be carefully selected according to the characteristics of the reaction, safety requirements, cost accounting and other factors.

2-%28Ethylsulphonyl%29imidazo%5B1%2C2-a%5Dpyridine-3-sulphonamide, this compound is on the market, and its price range is difficult to determine. The price of this compound is affected by various factors, such as manufacturing costs, supply and demand conditions, quality specifications, and business policies.
In terms of manufacturing costs, the price of raw materials and the complexity of synthesis are all affected. If the raw materials are rare, the preparation method is complicated, and multiple steps and special reagents are required, the cost will be high, and the price will follow.
Supply and demand are also critical. If the product is in high demand in the fields of medicine, chemical industry, etc., and the supply is limited, the price may rise; conversely, if the supply exceeds the demand, the price may drop.
Quality specifications are also related to the price. High purity, meeting strict standards, the price is often higher than that of ordinary products.
Furthermore, different merchants have different strategies and different pricing. Well-known large factories have high prices due to their excellent brand and quality control; small factories compete for the market and have low prices.
After checking the common chemical trading platforms and literature in the market, it is difficult to find the exact price range. Or because of its non-general common chemicals, there is little circulation in the market and the relevant quotations are thin. For more information, you can consult professional chemical suppliers, chemical raw material distributors, or ask in specific industry forums to get near real-time and accurate price information.

2-%28Ethylsulphonyl%29imidazo%5B1%2C2-a%5Dpyridine-3-sulphonamide, this is a chemical substance. However, when it comes to the potential side effects of this substance, it may be difficult to find details in ancient books, because modern chemical synthesis of substances has not yet come out in ancient times.
Today, according to scientific knowledge, the side effects of drugs or chemical substances often involve multiple ends. As far as its physiological function is concerned, it may affect liver and kidney function. The liver is the main center of detoxification in the human body, and the kidneys are responsible for excretion. If this substance affects its normal operation, or causes the accumulation of toxins in the body and metabolic disorders.
Furthermore, it may have an effect on the digestive system. Or cause nausea, vomiting, abdominal pain, diarrhea, etc., because the mucosa of the digestive system is sensitive and easily stimulated by foreign chemicals, resulting in digestive dysfunction.
The nervous system may also be affected by it. Such as dizziness, headache, drowsiness and even insomnia, etc., are possible. The neurotransmitter balance of the nervous system is delicate, and chemical substances may interfere with its signal transduction, resulting in abnormal neurological function.
Blood system, or affect the generation and function of blood cells, resulting in anemia, leukopenia, etc., so that the body's immunity and oxygen carrying capacity are reduced.
Although there is no corresponding record in ancient books, it is deduced from modern scientific thinking. Chemicals have complex effects in the body and have various side effects. When using or studying, carefully weigh their advantages and disadvantages, and observe and monitor them in detail to ensure safety.