2 Ethyloxy 5 Nitro Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-(ETHYLOXY)-5-(NITRO)PYRIDINE

    Specifications

    HS Code

    855875

    Chemical Formula C7H8N2O3
    Appearance Typically a solid
    Odor Unknown
    Melting Point Unknown
    Boiling Point Unknown
    Solubility In Water Unknown
    Solubility In Organic Solvents Unknown
    Density Unknown
    Flash Point Unknown
    Pka Unknown
    Logp Unknown
    Vapor Pressure Unknown
    Stability Unknown
    Hazard Class Unknown

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    General Information
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    Frequently Asked Questions

    As a leading 2-(ETHYLOXY)-5-(NITRO)PYRIDINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (ethoxy) -5- (nitro) pyridine?
    2- (ethoxy) -5- (propyl) compounds have many main uses and each has its own importance.
    In the field of organic synthesis, this compound plays a key intermediate role. For example, when building complex organic molecular structures, the unique chemical properties endowed by ethoxy and propyl groups can guide molecules to build according to specific paths through a series of organic reactions, such as nucleophilic substitution, addition reactions, etc. The oxygen atom in its ethoxy group has certain nucleophilicity and coordination ability, and can react with a variety of electrophilic reagents, thereby introducing other functional groups and expanding the structural complexity of the molecule; propyl group, as a group with specific steric resistance and electronic effects, has an important impact on the selectivity of the reaction and the stability of the product. When synthesizing bioactive natural product analogs, it is often used as a starting material or key intermediate to participate in the entire synthesis route, helping chemists to accurately construct the structure of the target molecule, providing an important material basis for new drug development and biological activity research.
    In the field of materials science, this compound can be used to prepare materials with special properties. With the characteristics of ethoxy and propyl groups, the surface properties, solubility, thermal stability, etc. of materials can be effectively regulated. When preparing polymer materials, it is introduced into the polymer chain as a monomer or modifier. Ethoxy groups can enhance the compatibility of materials with polar solvents and improve the processing properties of materials; propyl groups can adjust the crystalline properties and mechanical properties of materials, so that the final prepared materials meet specific requirements in terms of flexibility, strength, etc., to meet the performance requirements of different application scenarios such as packaging materials, electronic materials, etc.
    In the field of fragrance industry, 2- (ethoxy) -5- (propyl) compounds can emit specific aromas due to their unique molecular structures. The combination of ethoxy and propyl groups endows the molecule with unique volatile and odor characteristics, and can be used as a fragrance component to prepare various flavors. Its aroma may have a fresh, elegant or special charm, and can be used in perfumes, air fresheners, detergents and other products to add a pleasant fragrance to the product and enhance the market competitiveness of the product.
    What are the physical properties of 2- (ethoxy) -5- (nitro) pyridine?
    (2- (hydroxyethyl) -5- (carboxyl) pyridine) The physical properties of this substance are as follows:
    Its appearance is often a crystalline solid, and it is relatively stable at room temperature. In terms of solubility, it has a certain solubility in water. Due to the presence of polar groups in the molecule, such as carboxyl and hydroxyethyl, it can form hydrogen bonds with water molecules, which can promote its partial dissolution in water. However, in non-polar organic solvents, such as n-hexane, benzene, etc., the solubility is poor because the molecule is not completely non-polar.
    Melting point, after accurate determination, is roughly in a specific temperature range. This characteristic is of great significance for the identification and purification of this substance. In the process of heating, when the melting point is reached, the substance gradually changes from solid to liquid, and the intermolecular force changes.
    In terms of density, it has a specific value relative to water, and the density reflects the degree of close accumulation of its molecules. Compared with other similar substances, it has its own unique characteristics.
    In addition, its refractive index also has certain characteristics. When light passes through the substance, it will be refracted according to specific laws. The refractive index is related to the molecular structure of the substance and the distribution of the internal electron cloud. It can be used as an important indicator of physical properties to distinguish different substances or judge the purity of substances. In terms of stability,
    can maintain its own structure and properties under conventional conditions, but in the case of strong acids and bases, sensitive parts of the molecular structure, such as carboxyl and hydroxyethyl, may react, resulting in structural changes, which in turn affect its physical properties.
    What are the synthesis methods of 2- (ethoxy) -5- (nitro) pyridine?
    To prepare 2- (hydroxyethyl) -5- (carboxyl) pyridine, there are many ways to synthesize it, which are described in detail as follows:
    First, pyridine is used as the starting material, and the specific position of pyridine is introduced into the halogen atom by halogenation reaction. Subsequently, a nucleophilic substitution reaction occurs with the nucleophilic reagent containing hydroxyethyl, and then hydroxyethyl is introduced. Finally, the carboxyl group is constructed at another position through an appropriate oxidation step. This approach requires precise control of the reaction conditions to ensure the selectivity of the halogenation position and the smooth progress of the subsequent reaction.
    Second, starting from the benzene ring containing a suitable substituent, the pyridine ring is constructed through a multi-step cyclization reaction. Before the benzene ring is introduced into the precursor group that can be converted into hydroxyethyl and carboxyl groups. For example, through the Friedel-Crafts reaction, a specific substituent is introduced. After a series of reactions such as cyclization, oxidation, and reduction, it is gradually converted into the target 2- (hydroxyethyl) -5- (carboxyl) pyridine. The key to this route lies in the optimization of the conditions of the cyclization reaction and the control of the stability of the intermediates in each step of the reaction.
    Third, biosynthesis is adopted. Using specific microorganisms or enzymes, with suitable substrates as raw materials, the synthesis of the target product is achieved under mild reaction conditions. This method is green and environmentally friendly, and the selectivity is quite high. However, it is necessary to screen out high-efficiency biocatalysts and optimize the biological reaction system to improve the yield and efficiency.
    Fourth, a specific heterocyclic compound is used as the starting material, and the structure of the target molecule is gradually constructed through reactions such as ring opening, rearrangement, and substitution. For example, a heterocyclic ring containing a similar structure of pyridine is selected. After proper ring opening, hydroxyethyl and carboxyl groups are introduced, and then cyclized to generate 2- (hydroxyethyl) -5- (carboxyl) pyridine. This path requires in-depth understanding and control of the reactivity and selectivity of heterocyclic compounds.
    What are the precautions for 2- (ethoxy) -5- (nitro) pyridine in storage and transportation?
    Di- (ethoxy) -5- (carbonyl) When storing and transporting this substance, pay attention to many matters.
    When storing, the temperature and humidity of the environment are the first priority. Both ethoxy and carbonyl are sensitive to temperature and humidity. If the temperature is too high, it may cause changes in its chemical properties, triggering reactions such as decomposition and polymerization, which will damage its quality. If the humidity is too high, it is easy to cause deliquescence and change the properties of the substance. Therefore, when placed in a cool and dry place, the temperature should be controlled in the [suitable temperature range], and the humidity should be kept in the [suitable humidity range].
    Furthermore, it is necessary to avoid light. Light or induced luminescent chemical reactions affect the stability of the substance. It is advisable to use light-shielding packaging, such as dark containers, or wrap light-shielding materials on the outside of the package, and store in a dark place.
    Safety is the most important when transporting. Because it contains ethoxy and carbonyl, or has certain hazards, it must be carried out in accordance with the regulations on the transportation of dangerous chemicals. Choose suitable transportation tools to ensure that the container is well sealed and leak-proof. During loading and unloading, handle it with care. Do not subject to severe vibration or collision to avoid damage to the container.
    At the same time, fireworks should be strictly prohibited in transportation and storage places. Ethoxy and carbonyl substances are flammable, and they can be exposed to open flames, hot topics, or cause fires, or even explosions. And corresponding fire and emergency treatment equipment is required, just in case. Isolation from other chemicals is also essential to avoid reacting with them and causing adverse consequences.
    This di- (ethoxy) -5- (carbonyl) material should be treated with caution in terms of temperature, humidity, light, safety protection and isolation during storage and transportation to ensure its quality and safety.
    What is the market outlook for 2- (ethoxy) -5- (nitro) pyridine?
    Nowadays, there are di- (ethoxy) -penta- (propyl) products. What is the state of the market?
    Looking at the market, this di- (ethoxy) -penta- (propyl) product is quite impressive in the current market. Its use is quite extensive and involved in various industries.
    In the chemical industry, it is a key raw material for the production of a variety of chemicals. The products made may be unique and can meet different needs. Because it can combine with other products to produce new qualities, it is important for chemical craftsmen.
    In the pharmaceutical industry, it can also be seen. Or as an adjunct to pharmaceuticals, to assist in the formulation of medicines, to increase the effect of medicines. When a doctor is researching a medicine, he reviews its nature, uses it to the best of his ability, and hopes that it will be beneficial to the treatment of diseases.
    Furthermore, in the genus of material production, it can also be used. After skillful preparation, ordinary materials can be turned into extraordinary materials, so that the materials have better toughness and resistance, and are widely used in the manufacture of equipment and utensils.
    However, the market is impermanent, and this thing also faces various challenges. First, there are all competitors. Everyone knows the benefits, and they invest in it, and the supply of the market gradually increases. If the supply exceeds the demand, the price will fall, and the profit of the camp may decrease. Second, the times change, and new technologies and new things emerge one after another. If this thing cannot advance in time, it will be replaced by new things, for fear of losing its city.
    In summary, di- (ethoxy) -pent- (propyl) things, although they have their place in the city, need to be judged by the camp, make good use of their strengths, and avoid their shortcomings, in order to obtain long-term benefits in the market.