2-ethylmercapto-5-nitro-pyridine

2-Ethylmercapto-5-nitro-pyridine, Chinese name 2-ethylthio-5-nitropyridine, has a wide range of uses and is often a key organic synthesis raw material in the chemical and pharmaceutical fields.
In the field of Guanfu Chemical Industry, organic synthesis is complex and delicate, and 2-ethylthio-5-nitropyridine plays an important role in it. Its unique structure, ethylthio and nitro are attached to the pyridine ring, giving it special chemical activity. With this characteristic, it can participate in multiple organic reactions and lay the foundation for the creation of various complex organic compounds. For example, the preparation of specific drug intermediates, through their participation in the reaction, can precisely build the required molecular structure and pave the way for drug synthesis.
As for the pharmaceutical industry, many drug development relies on this compound. Because it can be transformed in a series and integrated into the molecular structure of the drug, it affects the key properties such as drug activity, solubility and stability. Or for the development of antibacterial drugs, use its chemical activity to build molecules that target specific bacteria, adding to the fight against diseases; or in the exploration of antiviral drugs, become the cornerstone of building effective molecular fragments, helping to develop efficient antiviral agents.
In summary, 2-ethylthio-5-nitropyridine is used in the chemical and pharmaceutical fields like a sophisticated tool in the hands of craftsmen. It plays an irreplaceable role in creating a variety of useful compounds and drugs and promotes the industry to move forward.

2-Ethylmercapto-5-nitropyridine, this is an organic compound. Its physical properties are unique, let me talk about them one by one.
Looking at its properties, under normal temperature and pressure, it is mostly in a solid state, and it is often crystalline. The quality is fine and regular, and it is in a bright state under light.
When it comes to the melting point, it is about a specific temperature range, which varies slightly due to the different preparation methods and purity. This melting point characteristic is crucial when identifying and purifying the compound.
In terms of boiling point, under specific pressure conditions, it reaches a certain temperature to start boiling. The value of this boiling point reflects the energy required for its gasification, and also helps in the separation and purification operation.
Solubility is also an important property. In organic solvents, such as common ethanol and ether, or have a certain solubility, but the degree of solubility can vary depending on the polarity and molecular structure of the solvent. In water, because its molecular structure contains hydrophobic groups, the solubility is poor.
Density is also a consideration factor, which may be different from water. This property is of great significance when it comes to liquid-liquid separation or specific gravity related operations.
In addition, its odor may have a certain particularity, but due to individual differences in olfaction, feelings may vary.
These physical properties are important guidelines for the operation of this compound in the synthesis, analysis and application fields, and can help chemists better control this compound.

There are several methods for the synthesis of 2-ethylmercapto-5-nitropyridine.
First, pyridine can be used. First, pyridine is nitrified with a suitable nitrifying agent, such as a mixed acid of concentrated nitric acid and concentrated sulfuric acid, under appropriate reaction conditions. The nitrogen atom of pyridine changes the electron cloud density distribution on the ring, so the nitro group mainly enters the specific position of the pyridine ring to form 5-nitropyridine. Then, 5-nitropyridine reacts with ethyl mercaptan under the catalysis of a base. The alkali can be selected from potassium carbonate, etc., in a suitable organic solvent, such as N, N-dimethylformamide (DMF), the nucleophilic substitution reaction occurs, and the appropriate position on the 5-nitropyridine ring is replaced by ethyl sulfhydryl group to obtain 2-ethylmercapto-5-nitropyridine.
Second, 2-halo-5-nitropyridine can be prepared first. Select a suitable halogenation reagent, such as halogen-containing acyl halide or hydrogen halide, and react with 5-nitropyridine to introduce halogen atoms at the second position of the pyridine ring. Subsequently, 2-halo-5-nitropyridine is reacted with ethyl mercaptan. Ethyl mercaptan can be obtained by reacting ethyl mercaptan with alkali metals such as sodium metal. This reaction is also nucleophilic substitution, and the halogen atom is replaced by ethyl mercapto to achieve the synthesis of 2-ethylmercapto-5-nitropyridine.
Third, start with 2-hydroxy-5-nitropyridine. With a suitable halogenated reagent, the 2-hydroxyl group is converted into a halogen atom to obtain 2-halogenated-5-nitropyridine. The subsequent steps are the same as the second method mentioned above, reacting with ethyl mercaptan to obtain the target product 2-ethylmercapto-5-nitropyridine by nucleophilic substitution reaction. Different synthesis methods have their own advantages and disadvantages, and the most suitable route should be selected according to actual needs, such as the availability of raw materials, the difficulty of reaction conditions, and the high and low yield.

I look at your question, but I am inquiring about the price range of 2 - ethylmercapto - 5 - nitro - pyridine in the market. Then check "Tiangong Kaiwu", this book is written by Song Yingxing in the Ming Dynasty, which contains various techniques of agriculture and handicraft industry in detail, and does not involve the price of this chemical.
In today's world, the price of this chemical varies due to many reasons. First, the cost of production, such as the price of raw materials, energy consumption, and labor rewards, all affect its price. If raw materials are rare, the cost must be high, and the price will follow. Second, the supply and demand of the market. If more supply is less, the price will rise; if the supply exceeds the demand, the price will be depressed. Third, the quality is good or bad. < Br >
And its use is also related to the price. If used in high-end fields such as pharmaceuticals, due to strict requirements, the price must be high; if used in general chemicals, the price may be slightly lower.
Although there is no exact price range, it is common sense to infer that in the fine chemical market, the price of such special chemicals may range from hundreds to thousands of yuan per kilogram. But this is only speculation, and the actual price needs to be determined by consulting the chemical raw material supplier in detail.

2-Ethylmercapto-5-nitropyridine is a kind of organic compound. Its storage conditions are crucial, which is related to the stability and quality of this substance.
This substance should be stored in a cool and dry place. In the shade, avoid direct sunlight. The sun is hot and contains a lot of energy. Direct exposure can easily cause the compound molecules to gain energy and cause structural changes, or cause reactions to occur, damaging its chemical properties. Dry place, no water vapor intrusion. Water vapor, a medium for many chemical reactions, also exists in water, or causes reactions such as hydrolysis, which damage its original structure.
Furthermore, storage requires good ventilation. Well ventilated, it can avoid the accumulation of harmful gases. If this substance decomposes for some reason to produce harmful gases, ventilation can quickly disperse it to ensure the safety of the storage environment and prevent accidents when the gas concentration is high.
And should be kept away from fire sources and oxidants. Fire sources, the source of energy, are also encountered, this substance may burn or explode, causing serious accidents. Oxidants have strong oxidizing properties. When they meet 2-ethylmercapto-5-nitropyridine, they can easily cause oxidation reactions and change their chemical composition and properties.
It must be stored in a sealed container. Sealing can prevent contact with outside air and prevent the reaction of oxygen, carbon dioxide, etc. in the air. It can also prevent this substance from evaporating and escaping, causing loss and environmental pollution.
During access and storage, strict operating procedures should be followed, and special protective equipment, such as gloves, goggles, etc. should be used to ensure the safety of operators. In this way, proper storage can be used to maintain a good chemical state of 2-ethylmercapto-5-nitropyridine.