2-ethyl-4-cyanopyridine

2-Ethyl-4-cyanopyridine, Chinese name 2-ethyl-4-cyanopyridine, is widely used and has important applications in various fields of chemical industry.
Its primary use is in pharmaceutical synthesis. As the old saying goes, it is the key raw material for processing good medicines. In the pharmaceutical industry, through a series of delicate chemical reactions, it can be ingeniously converted into compounds with specific pharmacological activities. These compounds may become effective ingredients in the treatment of various diseases, such as drug development for some difficult and complicated diseases. 2-ethyl-4-cyanopyridine can play a cornerstone role, just like the rock that builds a mansion, indispensable.
Furthermore, in the field of materials science, it can also be seen. In the preparation of special materials, 2-ethyl-4-cyanopyridine can be used as a unique reactive monomer. Through reactions such as polymerization, it can endow materials with unique properties, such as enhancing the stability of materials and improving their optical properties. Just like giving materials a unique "endowment" in a unique way, it can show excellent performance in specific application scenarios.
In addition, in the field of organic synthetic chemistry, 2-ethyl-4-cyanopyridine is also often used as a key intermediate. With its special molecular structure, it can guide chemical reactions in the desired direction and synthesize many organic compounds with complex structures and special functions. It is like a "beacon" in the palace of organic synthesis, helping chemists explore a wider world of compounds.
In short, 2-ethyl-4-cyanopyridine plays a crucial role in the fields of medicine, materials and organic synthesis, and is an indispensable "treasure" in the chemical industry.

There are various ways to synthesize 2-ethyl-4-cyanopyridine. One is to take pyridine as a group and obtain it through alkylation and cyanidation. First, pyridine and halogenated ethane are alkylated in the presence of suitable bases and solvents to obtain 2-ethylpyridine. This step requires careful selection of bases, such as potassium carbonate, sodium carbonate, etc., and reaction at appropriate temperatures and durations to increase the yield of the product. Afterwards, 2-ethylpyridine and cyanide reagents, such as potassium cyanide, sodium cyanide, etc., are cyaninated with the help of catalysts, and then 2-ethyl-4-cyanopyridine is obtained.
The second way can start from aromatic compounds containing corresponding substituents. Taking benzene derivatives with specific substituents as an example, pyridine rings are formed by cyclization reaction, and then modified to introduce ethyl and cyano groups. In this process, the control of cyclization conditions is crucial. Temperature, type and dosage of catalysts are all related to the efficiency and selectivity of pyridine ring formation. < Br >
Or it can be obtained by the conversion of 2-ethyl-4-pyridinecarboxylic acid through dehydration and cyanidation. First, 2-ethyl-4-pyridinecarboxylic acid is reacted with a dehydrating agent, such as phosphorus pentoxide, under specific conditions, and the corresponding pyridine derivative is decarboxylated to obtain the corresponding pyridine derivative, and then cyanide is introduced by cyanation.
Furthermore, the coupling reaction catalyzed by transition metals is also a good strategy for synthesis. For example, the coupling reaction of halogenated pyridine derivatives with reagents containing ethyl and cyano is carried out in the presence of transition metal catalysts and ligands such as palladium and nickel. This path requires high precision regulation of reaction conditions, and the polarity of the solvent, the strength and dosage of the base all have a significant impact on the reaction process and product purity.
All these synthesis methods have their own advantages and disadvantages. According to actual needs, factors such as the availability of raw materials, cost, and difficulty in controlling reaction conditions must be considered to determine the optimal synthesis path.

2-Ethyl-4-cyanopyridine, or 2-ethyl-4-cyanopyridine, is an important compound in the field of organic chemistry. This substance has unique physical properties, and in-depth investigation of it is of great significance in many fields such as organic synthesis and materials science.
In terms of appearance, 2-ethyl-4-cyanopyridine is often colorless to light yellow liquid, with pure and uniform texture. Under normal lighting conditions, it presents a clear and transparent state without obvious impurities and turbidity. Its color is light yellow, or due to the absorption and reflection of light by specific chemical bonds and functional groups in the molecular structure. < Br >
In terms of boiling point, the boiling point of this compound is quite high, about 260-270 ° C. This property is due to the existence of strong interaction forces between molecules, such as van der Waals forces and hydrogen bonds. A higher boiling point means that more energy is required to overcome the attractive forces between molecules, causing them to change from liquid to gaseous. This property is of great significance in chemical operations such as distillation, separation and purification, allowing operators to distinguish from other compounds with large differences in boiling points and achieve efficient separation.
The melting point is usually around -20 ° C, which is relatively low, indicating that the substance exists stably in liquid form at room temperature. The lower melting point reflects that the arrangement of molecules is not extremely close and orderly, and the thermal motion of molecules is relatively free.
The density of 2-ethyl-4-cyanopyridine is about 1.02-1.06 g/cm ³, which is slightly greater than the density of water. This means that when mixed with water, it will sink to the bottom of the water, which can be used as a basis in liquid-liquid separation operations.
Solubility is also one of the important physical properties. The compound is slightly soluble in water because water is a polar solvent, while 2-ethyl-4-cyanopyridine contains a polar cyano group, but the presence of ethyl makes its overall polarity relatively weak, and the polarity difference with water is large. According to the principle of "similar miscibility", its solubility in water is limited. However, it is well soluble in common organic solvents such as ethanol, ether, chloroform, etc. The polarity and molecular structure of these organic solvents are more compatible with 2-ethyl-4-cyanopyridine, so they can be miscible with each other.
In addition, 2-ethyl-4-cyanopyridine also has a certain volatility. Although the volatilization rate is not fast, it will still be partially volatilized when placed in an open environment for a long time. Its vapor pressure is relatively low at room temperature, which is related to its high boiling point and relatively weak intermolecular forces.
In summary, these physical properties of 2-ethyl-4-cyanopyridine are interrelated and together determine their behavior and performance in various chemical reactions, separation operations, and practical applications. It is essential for in-depth research and rational application of this compound.

I have not found the relevant price record of "2-ethyl-4-cyanopyridine" in "Tiangong Kaiwu". However, looking at "Tiangong Kaiwu", the manufacture and origin of many crafts and various products, do not specify the market price of this chemical category.
In today's world, the price of chemical substances often varies according to quality, purity, supply and demand, origin and sales channels. If you want to know the exact market price of "2-ethyl-4-cyanopyridine", you should consult the supplier of chemical raw materials, the seller of chemical reagents, or the chemical product trading platform for details. Its price may change from time to time and is not constant. Although "Tiangong Kaiwu" is a masterpiece of ancient Chinese science and technology, it is difficult to relate its content to today's chemical market prices due to different times.

2-Ethyl-4-cyanopyridine (2-ethyl-4-cyanopyridine) is an important compound in organic chemistry. Its storage conditions are crucial to the stability and quality of this compound.
If this compound is stored, it should first be placed in a cool place. In a cool place, the temperature is suitable, and it will not cause chemical reactions due to excessive temperature, causing it to decompose or deteriorate. If it is in a high temperature environment, the molecular movement will intensify, or the chemical bond will be broken, which will damage its chemical structure.
It needs to be dried every time. Moisture is the enemy of many organic compounds, and 2-ethyl-4-cyanopyridine is no exception. Moisture can cause reactions such as hydrolysis and change its chemical properties. Therefore, it can be stored in a dry place to avoid contact with water and maintain its chemical stability.
Furthermore, it should be placed in a well-ventilated place. If it is well ventilated, it can dissipate harmful gases that may be generated in time, and avoid its accumulation in a limited space, reducing the risk of explosion or poisoning.
It should also be noted that it should be stored away from fire sources and oxidants. 2-ethyl-4-cyanopyridine has certain flammability and is easy to catch fire and burn in case of fire sources. The oxidant can react violently with the like, causing danger.
In short, store 2-ethyl-4-cyanopyridine in a cool, dry, well-ventilated place away from fire and oxidants, so that it can be properly preserved and chemically stable for future scientific research or industrial production.