2-Ethoxy-5-pyridinecarboxylic acid

2-Ethoxy-5-pyridinecarboxylic acid is a kind of organic compound. Looking at its structure, it contains a pyridine ring, ethoxy group and carboxyl group.
The physical properties of this compound are mostly solid under normal conditions, or powder due to impurities. Its melting point, boiling point and other properties are affected by intermolecular forces. Intramolecular carboxylic groups can form hydrogen bonds, causing the melting point to rise. Due to the presence of polar groups, the solubility in polar solvents (such as water and alcohols) may be higher than that in non-polar solvents (such as alkanes).
In terms of chemical properties, carboxylic groups are acidic and can neutralize with bases to form corresponding carboxylate and water. It can also be esterified with alcohols under acid catalysis to form ester compounds. This reaction is reversible and requires controlled conditions to increase the yield. Ethoxy groups are relatively stable, but under specific conditions (such as strong acidity or alkalinity and high temperature), ether bond cleavage may occur. The nitrogen atom of the pyridine ring has a certain alkalinity and can react with acids to form salts, and the pyridine ring can undergo electrophilic substitution reactions. Affected by carboxyl groups and ethoxy groups, the substitution reaction has specific selectivity.
The chemical properties of 2-ethoxy-5-pyridine carboxylic acid are derived from the characteristics of each group in its structure. It has the potential to construct complex compounds in the field of organic synthesis and may have applications in pharmaceutical chemistry, materials science and other fields.

2-Ethoxy-5-pyridinecarboxylic acid is widely used. In the field of medicine, it is often used as a key intermediate to help synthesize specific drugs. Due to its unique chemical structure, it can interact with specific biological targets, so in the process of new drug development, it lays the foundation for the creation of drugs with high activity and selectivity.
In the chemical industry, it also plays an important role. It can be used to prepare high-performance polymer materials, such as monomers or modifiers for polymerization reactions, endowing materials with characteristics such as good thermal stability, chemical stability and mechanical properties, which greatly expands the application scope of materials.
Furthermore, in agricultural chemistry, it can be used as an important raw material for the synthesis of new pesticides. With its chemical properties, pesticide products that are efficient in pest control and relatively environmentally friendly can be derived, contributing to the green and sustainable development of agriculture. In short, 2-ethoxy-5-pyridinecarboxylic acid has important uses in many fields and is of great significance in promoting the development of related industries.

The synthesis of 2-ethoxy-5-pyridinecarboxylic acid is a key research in the field of organic synthesis. Today, the ancient classical Chinese text of "Tiangong Kaiwu" is described in detail as follows.
To obtain this compound, the common method is to use pyridine as the starting material. Prior to the specific position of pyridine, the carboxyl group is precisely introduced. The introduction of this carboxyl group may be through nucleophilic substitution reaction to make pyridine interact with suitable carboxylation reagents. For example, using halogenated carboxylic acid esters as reagents, under the catalysis of strong bases, the halogen atoms leave, and the specific carbon atoms of pyridine are connected to the carboxyl group to form the intermediate of pyridinecarboxylate. This process requires controlling the reaction temperature, time and reagent ratio to increase the yield.
Then, the pyridinecarboxylic acid ester is converted into a pyridinecarboxylic acid. The pyridinecarboxylic acid ester can be treated with a strong alkali solution by basic hydrolysis, so that the ester bond is broken and the corresponding carboxylic acid is formed. After acidification, the carboxylic acid is converted into the target pyridinecarboxylic acid.
As for the introduction of ethoxy groups, it can be carried out after the introduction of carboxylic groups. With halogenated ethane as the ethoxylation reagent, in the presence of a base, the halogen atom undergoes nucleophilic substitution reaction with the hydroxyl group or other leaving groups at a specific position on the pyridine ring, and the ethoxy group is successfully introduced.
There are also other methods, which can first construct the pyridine derivative For example, using suitable ethoxylpyridine as raw material, using suitable carboxylating reagents, such as carbon dioxide or carboxylic acid derivatives, under suitable reaction conditions, ethoxylpyridine is carboxylated to obtain 2-ethoxy-5-pyridinecarboxylic acid.
All these synthesis methods require fine regulation of the reaction conditions, paying attention to the purity of raw materials, reaction temperature, pH, catalyst and many other factors, in order to achieve efficient and high-purity synthesis to meet the needs of different fields for 2-ethoxy-5-pyridinecarboxylic acid.

I have not obtained the exact market price of 2 - Ethoxy - 5 - pyridinecarboxylic acid. This compound belongs to the field of organic synthesis, and its price is determined by many factors.
The cost of the raw material is one of the main reasons for this. If the source of the starting material required to prepare this acid is scarce or difficult to prepare, the price must be high, which in turn drives up the cost of the target product. For example, the starting material needs to be synthesized in multiple complex steps or obtained from special channels, and the price will increase significantly.
The difficulty and steps of synthesis are also critical. If the synthesis route is lengthy, requires multiple steps, harsh reaction conditions (such as high temperature, high pressure, low temperature, or specific catalysts), and the yield of each step is limited, the overall preparation cost will increase significantly, and the price will be high.
The supply and demand situation of the market also affects the price. If many scientific research institutions and enterprises have strong demand for it, but the supply is relatively insufficient, the price will increase; conversely, if there is little demand and excess supply, the price will decrease.
In addition, different suppliers have different prices due to production scale, technical level, and operating costs. Large-scale production enterprises may have lower costs and more competitive prices due to scale effects; while small suppliers may have higher prices due to higher costs.
For accurate prices, please consult chemical product suppliers, reagent companies, or search on professional chemical product trading platforms to obtain the latest and realistic price information.

2-Ethoxy-5-pyridinecarboxylic acid is an organic compound. When storing and transporting, be sure to pay attention to the following numbers:
First, the storage environment should be cool and dry. If this compound is exposed to humid air, it may be hydrolyzed by moisture, resulting in deterioration of quality. Due to moisture or reaction with certain groups in the molecule, its chemical structure and properties should be changed. Therefore, it should be stored in a dry and ventilated place, away from water sources and places where water vapor is prone to agglomeration.
Second, avoid open fires and hot topics. Many organic compounds are flammable, as is 2-ethoxy-5-pyridinecarboxylic acid. In case of open flame, hot topic, or cause combustion, or even explosion, endangering the safety of personnel and facilities. Fireworks should be strictly prohibited at storage and transportation sites, and temperature should be controlled to prevent the instability of compounds due to excessive temperature.
Third, it should be stored in isolation from oxidants, acids, bases, etc. Because its chemical structure contains specific functional groups, or reacts violently with these substances. If it comes into contact with oxidants, or initiates oxidation reactions, it destroys the molecular structure; reacts with acids and bases, or changes its chemical properties, affecting the performance of use. Therefore, different chemicals need to be separated during storage to prevent accidental reactions.
Fourth, ensure that the packaging is intact during transportation. Damage to the packaging or leakage of compounds, pollution of the environment, or cause safety accidents. When loading and unloading, it should be handled with care to prevent the package from being damaged by impact and extrusion. And transportation vehicles need to be equipped with corresponding fire equipment and leakage emergency treatment equipment to deal with emergencies.