2-cyano-5-nitropyridine

2-Cyano-5-nitropyridine is also an organic compound. Its physical properties are quite important and are related to many chemical applications.
The properties of this compound are mostly solid under normal conditions. Looking at its appearance, it may be a light yellow to yellow crystalline powder with bright color and easy to distinguish. It has a specific melting point. After fine measurement, the melting point is within a certain temperature range. This temperature range is of great significance for the determination of its purity and stability. Due to the precise value of the melting point, it can reflect the strength of the intermolecular forces of the compound and the regularity of the crystal structure.
Solubility is also one of the key physical properties. In organic solvents, such as common ethanol, acetone, etc., 2-cyano-5-nitropyridine exhibits a certain solubility. In ethanol, under appropriate temperature and stirring conditions, it can be partially dissolved to form a uniform solution. This solubility characteristic provides convenience for its application as a reactant or intermediate in organic synthesis reactions. Because in the solution system, the chance of collision between molecules increases, which is conducive to the progress of the reaction.
However, in water, its solubility is poor. Water is a polar solvent, and the molecular structure of 2-cyano-5-nitropyridine makes it difficult to form an effective interaction with water molecules, so it is not easily soluble in water. This property can be exploited in the process of separation and purification, and the separation of the compound from other water-soluble impurities can be achieved by the extraction operation of water and organic solvents.
In addition, the density of 2-cyano-5-nitropyridine also has a specific value. Although the exact density value needs to be determined by professional instruments, in general, its density is similar to that of common organic compounds. The density is of great significance for determining the phase state and distribution of the compound in the process of mixing or phase separation of liquids.
In summary, the physical properties of 2-cyano-5-nitropyridine, including its appearance, melting point, solubility, and density, are interrelated and together determine its application and treatment in the field of chemistry.

2-Cyano-5-nitropyridine is one of the organic compounds. Its chemical properties are very interesting, so let me explain in detail for you.
This substance has a certain stability, but it is also active because it contains cyanoyl (-CN) and nitro (-NO 2O) functional groups. Cyano is nucleophilic and can participate in many nucleophilic substitution reactions. Under appropriate conditions, cyano can be hydrolyzed into carboxyl groups (-COOH). In case of strong acid or strong base aqueous solution, it can be converted into corresponding carboxylic acid derivatives after hydrolysis process. This reaction is often an important way to prepare carboxyl-containing compounds in organic synthesis. The
nitro group is also a key functional group, which has strong electron-withdrawing properties, which can reduce the electron cloud density of the pyridine ring and increase the difficulty of electrophilic substitution reaction on the pyridine ring. On the contrary, the nucleophilic substitution reaction on the pyridine ring is more likely to occur due to the electron-withdrawing effect of the nitro group. For example, nucleophiles can attack the position adjacent to or opposite the nitro group on the pyridine ring, and nucleophilic substitution occurs, introducing new functional groups.
2-cyano-5-nitropyridine can also participate in the reduction reaction. Nitro can be gradually reduced, first to nitroso (-NO), and then to amino (-NH2O). If suitable reducing agents, such as iron and hydrochloric acid, lithium aluminum hydride, etc., can achieve selective reduction of nitro groups, which is extremely useful in the preparation of amino-containing pyridine derivatives.
In addition, its cyanyl group can also be reduced, and under specific reduction conditions, it can be converted into amine methyl (-CH ² NH ²) and other groups, further enriching the diversity of its reactions, providing many possibilities for organic synthesis chemists to construct complex pyridine compounds.
In summary, 2-cyano-5-nitropyridine exhibits rich and diverse chemical properties in organic chemical reactions due to the characteristics of functional groups, providing many valuable reaction paths and products for the field of organic synthesis.

2-Cyano-5-nitropyridine is a crucial chemical substance in the field of organic synthesis. Its main uses involve a wide range of aspects.
Bearing the brunt, in the field of medicinal chemistry, this substance is a key intermediate. The unique chemical properties of the Geynepyridine ring system and cyano and nitro groups enable it to participate in many delicate chemical reactions to construct complex molecular structures with biological activities. For example, in the development of antibacterial and antiviral drugs, 2-cyano-5-nitropyridine can be subtly introduced into the target molecular structure through a series of carefully designed reaction steps, thereby imparting specific pharmacological activities to the drug and assisting in the treatment of diseases.
Furthermore, in the field of materials science, 2-cyano-5-nitropyridine also plays an indispensable role. It can be used as an important starting material for the synthesis of special functional materials. After appropriate chemical modification and polymerization, materials with unique optical and electrical properties can be prepared. For example, in the preparation of organic optoelectronic materials, the use of their structural properties can regulate the energy level structure and charge transport properties of the materials, providing strong support for the development of cutting-edge technologies such as organic Light Emitting Diodes and solar cells.
In addition, in pesticide chemistry, 2-cyano-5-nitropyridine also has extraordinary performance. It can be used as a key component in the synthesis of new and efficient pesticides. With its chemical activity, it can develop specific pesticides for specific pests or weeds, play an important protective role in agricultural production, and help improve crop yield and quality.
In summary, 2-cyano-5-nitropyridine, with its unique chemical structure, has shown irreplaceable uses in many fields such as medicine, materials, and pesticides, promoting scientific and technological progress and industrial development in related fields.

The synthesis method of 2-cyano-5-nitropyridine is not directly described in the ancient book "Tiangong Kaiwu", but it can be deduced from the ancient ideas and modern chemical knowledge.
First, pyridine can be started. First, pyridine is co-heated with mixed acids (sulfuric acid and nitric acid) to carry out nitrification. This step requires temperature control, because pyridine is more sensitive to nitrification, and high temperature can easily lead to polynitrification or pyridine ring destruction. After 5-nitropyridine is obtained, it is reacted with cyanide reagents such as cuprous cyanide in the presence of suitable solvents and bases. The alkali can promote the cyano substitution reaction, such as potassium carbonate, etc. The solvent can be N, N-dimethylformamide, through which 2-cyano-5-nitropyridine can be obtained.
Second, take 2-methyl-5-nitropyridine as the starting material. First oxidize the methyl group to the carboxyl group, and use a strong oxidant such as potassium permanganate to obtain 2-carboxyl-5-nitropyridine. Then the carboxyl group is converted into a cyano group, and the acid chloride can be obtained by reacting with sulfoxide chloride first, and then reacting with cyanizing reagents such as sodium cyanide under appropriate conditions to obtain the target product. < Br >
Third, it can also be modified from natural products or other derivatives containing pyridine rings. If there are suitable natural pyridine derivatives, cyano and nitro groups are gradually introduced through selective functional group transformation. This rule requires fine control of reaction conditions and selectivity to achieve the synthesis of the target product.

2-Cyano-5-nitropyridine is a chemical substance, and many things must be paid attention to when storing and transporting.
One is related to storage. This chemical should be stored in a cool, dry and well-ventilated place. Because of its certain chemical activity, if the ambient temperature is too high, it may cause a chemical reaction and cause it to deteriorate; if the humidity is too high, it may absorb moisture and affect the quality. And it needs to be kept away from fires and heat sources, because it is exposed to open flames, hot topics or the risk of combustion and explosion. It should be stored separately from oxidants, acids, bases, etc., and must not be mixed to prevent mutual reaction. The storage area shall be equipped with suitable materials to contain leaks, so as to prevent timely handling of accidental leaks.
Second, regarding transportation. Be sure to ensure that the packaging is complete and sealed before transportation. Packaging materials shall be able to effectively prevent its leakage and volatilization. During transportation, ensure that the container does not leak, collapse, fall, or damage. The speed of the vehicle should not be too fast, and avoid sudden braking to prevent package damage due to collision. During transportation, it should also follow the prescribed route and do not stop in densely populated areas and residential areas. Transportation vehicles shall be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In the event of an accident, they can be responded to in a timely manner.
In conclusion, the storage and transportation of 2-cyano-5-nitropyridine must be carried out in strict accordance with relevant safety procedures to ensure the safety of personnel and the environment from pollution.