2-Cyano-4-methoxypyridine

2-Hydroxy-4-methoxybenzaldehyde, although this substance is not detailed in "Tiangong Kaiwu", its uses cover the following ends based on the ancient chemical process and the understanding of the materials used.
One, or used for dyeing and weaving. In ancient dyeing workshops, natural things were often sought as dyes. 2-Hydroxy-4-methoxybenzaldehyde has a special chemical structure, or can interact with fabric fibers to show various colors. And its structure is stable, and the color of dyeing may not fade for a long time, so that the color of the fabric is still fresh over the years. In the weaving and dyeing industry, it helps the beauty of color and the strength of quality.
Second, in the way of medicine, it may have its use. Ancient healers studied Materia Medica and explored the properties of various substances to treat diseases. This compound may have certain pharmacological activity and can regulate human diseases. Or it can inhibit bacteria and anti-inflammation, apply sores, stop their swelling and pain, and heal their ulcers; or it can be added to decoction powder, adjust qi and blood, and viscera, and treat the body's violation. Although there is no confirmed evidence contained in ancient books, it is deduced by chemical pharmacology that hydroxyl, methoxy and other groups in its structure may be the source of efficacy.
Third, in the incense path, it may also be involved. The ancients emphasized incense, using aromatherapy rooms, nourishing nature, and sacrificing. 2-Hydroxy-4-methoxybenzaldehyde may have a unique aroma and can be made into a fragrance. Its fragrance is either quiet and elegant, or rich and long, and when burned, it will generate fragrance all over the room, which can please the body and mind, create a quiet and peaceful environment, and add a touch of unique fragrance to the fragrance.
Fourth, in the ancient lacquer-making process, it may have its own uses. Excellent lacquer art, seeking the quality, color, beauty and durability of the lacquer. This compound may be integrated with various ingredients in the lacquer to improve the performance of the lacquer. Or increase its luster, making the surface of the lacquer like a mirror, shining; or strengthen its toughness, making the lacquer not easy to crack and prolong its survival.

2-% hydroxy-4-methoxybenzaldehyde, this substance is light yellow in color and is often crystalline. Its melting point is moderate, between 112 and 114 degrees Celsius. This property allows it to change its shape at a specific temperature, which can be judged by its purity.
In terms of solubility, it is slightly soluble in cold water, better in hot water, and easily soluble in organic solvents such as alcohols and ethers. This solubility makes it effective in many organic reactions, and it can be dispersed and reacted with the power of solvents.
It has a special aroma and can be used for fragrance blending, adding a unique flavor to daily chemical, food and other industries. < Br >
Because its molecules contain active groups such as hydroxyl groups and aldehyde groups, the chemical properties are active. Hydroxyl groups can undergo esterification, etherification and other reactions, and aldehyde groups can participate in oxidation, reduction, condensation and many other reactions. It has a wide range of uses in the field of organic synthesis and is often used as a key intermediate for the preparation of complex organic compounds.
The stability of this compound has a certain limit, and its structure or properties are changeable when exposed to light, heat or a specific chemical environment. Therefore, it needs to be stored in a cool, dry and dark place to prevent deterioration, maintain its original physical and chemical properties, and ensure its application effectiveness.

2-% hydroxyl-4-methoxybenzaldehyde, this substance has unique chemical properties. It is active and has a wide range of uses in the field of organic synthesis.
Looking at its structure, the hydroxyl group and the methoxy group are connected to the benzene ring, and the aldehyde group is also at a specific position, this structure endows it with unique reactivity. Hydroxyl groups can participate in many reactions, such as ester formation reactions, encountering acyl chloride or acid anhydride. Under suitable conditions, the hydrogen of the hydroxyl group is replaced by the acyl group to form the corresponding ester, which is a common path for the construction of ester bonds in organic synthesis. The presence of the
methoxy group also has an effect. It has a donor electron effect, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution For example, when interacting with halogenating agents, halogen atoms are more likely to replace hydrogen atoms at specific positions on the benzene ring, and the reactivity and check point selectivity are regulated by both methoxy and hydroxyl groups.
The aldehyde group is an important functional group of this compound and has typical aldehyde properties. Oxidation reaction can occur. Under the action of weak oxidants such as Torun reagent or Feilin reagent, the aldehyde group is oxidized to a carboxyl group to generate 2-hydroxy-4-methoxybenzoic acid. Reduction reaction can also occur. Treated with a suitable reducing agent, the aldehyde group can be converted into a hydroxy group to obtain 2-hydroxy-4-methoxybenzyl alcohol.
In addition, 2-hydroxy-4-methoxybenzaldehyde can be used as a key intermediate to participate in the construction of complex organic compounds. Condensation with active hydrogen-containing compounds can form new carbon-carbon or carbon-hetero bonds, laying the foundation for the synthesis of natural products, drugs and functional materials. In short, due to its unique structure and diverse reactivity, it is of great significance in the field of organic chemistry.

To prepare 2-cyano-4-methoxyaniline, there are many methods.
First, it can be obtained by reducing the corresponding nitro compound. First, take a suitable nitrobenzene derivative, in a suitable reaction system, choose a reduction system composed of iron powder, zinc powder and other metals and acids, or by catalytic hydrogenation to gradually convert the nitro group into an amino group. This process requires attention to the control of the reaction conditions. Temperature, pH, etc. are all related to the purity and yield of the product.
Second, it can be formed by the cyanation and methoxylation of halogenated aromatics. First take halogenated aromatics, use cyanide reagents, such as potassium cyanide, sodium cyanide, etc., with the help of phase transfer catalysts, introduce cyanyl groups; then use methoxylating reagents, such as sodium methoxide, etc., to replace the halogen atoms with methoxy groups. The optimization of the reaction sequence and reaction conditions in each step is very important to avoid side reactions.
Third, the method of diazotization can be used. First, the compound containing amino groups is made into a diazonium salt, and then reacts with cyanyl reagents and methoxylating reagents in a specific order. In this process, the stability of the diazonium salt needs special attention, and the operation should be carried out at low temperature to prevent the decomposition of the diazonium salt and affect the formation of the product.
Fourth, aniline derivatives are used as starting materials, and the amino group is protected by acylation, followed by cyanylation, methoxylation, and finally deprotection, and the target product can also be obtained. This route requires fine planning of each step of the reaction to ensure smooth protection and deprotection steps, and precise control of the selection and dosage of reaction reagents.
All methods have advantages and disadvantages. In actual synthesis, the optimal method should be carefully selected according to factors such as the availability of raw materials, cost, and difficulty in operation, and the reaction conditions should be carefully adjusted to obtain the ideal yield and purity.

2-% hydroxy-4-methoxybenzaldehyde, the price of this product in the market varies depending on quality, supply and demand.
If it is of high quality and purity, it needs to be used in the field of fine chemical and pharmaceutical synthesis. In high-end pharmaceutical research and development, the price per gram can reach tens of gold, or even hundreds of gold. This is because of its difficult preparation method, multiple precision processes, and strict requirements for raw materials and equipment, so the price is high.
And general industrial grade, the purity is slightly inferior, and it is used in fragrances, dyes and other industries. When it is sold in bulk, the price per kilogram may be in the hundreds of gold. This is because industrial users have slightly lower requirements for purity, the preparation scale can be larger, the cost is slightly reduced, and the price is also reduced.
However, the supply and demand of the market is also the key. If the pharmaceutical, spice and other industries are prosperous at a certain time, and the demand exceeds the supply, the price will rise; on the contrary, if the production is more and less, the price may drop. And the cost of origin and transportation also affects the price. If it is shipped from a long distance, the price will increase due to the addition of freight.
In summary, the price of 2-% hydroxy-4-methoxybenzaldehyde fluctuates between changes in market conditions.