As a leading 2-Cyano-4-chloropyridine, 4-Chloro-2-cyanopyridine, 4-Chloropicolinonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-Cyano-4-chloropyridine, 4-Chloro-2-cyanopyridine and 4-Chloropicolinonitrile?
2-Cyano-4-chloropyridine, 4-chloro-2-cyanopyridine, and 4-chloropyridine-formonitrile refer to the same chemical substance. Its main uses are wide, in the field of medicine, and it is a key intermediate for many drug synthesis. For example, in the preparation of some antibacterial drugs, it plays an indispensable role. Through specific chemical reactions, it participates in the construction of drug active structures and helps to improve the antibacterial efficacy of drugs.
In the field of pesticides, it is also an important raw material. With the help of a series of synthesis steps, pesticide products with high insecticidal, bactericidal or herbicidal activities can be prepared, which is of great significance for ensuring the healthy growth of crops and increasing yields. < Br >
In the field of materials science, it also has its place. It can be used to synthesize organic materials with special properties, such as optoelectronic materials, etc. These materials show unique advantages in electronic devices, optical devices, etc., and promote the progress of related fields.
This substance plays an important role in the field of chemical synthesis. As a key intermediate, it can derive a variety of compounds with different functions and application values, and has far-reaching impact on the development of industries such as medicine, pesticides and materials.
What are the physical properties of 2-Cyano-4-chloropyridine, 4-Chloro-2-cyanopyridine and 4-Chloropicolinonitrile?
2-Cyano-4-chloropyridine, 4-chloro-2-cyanopyridine, and 4-chloropyrolinitrile refer to the same substance. Its physical properties are as follows:
This substance is mostly white-like to light yellow crystalline powder under normal conditions. Looking at its properties, it is fine and uniform in quality, with a positive and pure color, just like a natural state. Its melting point range is usually between 70 ° C and 73 ° C. It melts when heated, and it melts between transformations. In terms of solubility, it is slightly soluble in water, and it is the source of all things. However, this substance has limited affinity with it and can only melt less. However, it is easily soluble in organic solvents such as ethanol, ether, acetone, etc. In organic agents, like a duck to water, it fuses seamlessly.
Its stability is also considerable. Under normal temperature and pressure, it can maintain its properties and is not easy to change. However, when encountering an open flame or hot topic, you need to be cautious. It may have the risk of burning, which is a warning of physical properties. Its vapor mixes with air, or becomes an explosive mixture, and it will explode when encountering a fire source. This is another risk.
In addition, this substance is also careful when stored. It should be placed in a cool and ventilated place, protected from light and shade, and away from fire and heat sources to prevent unexpected changes. In this way, it can maintain its physical integrity and prepare it for the required use.
What are the synthesis methods of 2-Cyano-4-chloropyridine, 4-Chloro-2-cyanopyridine and 4-Chloropicolinonitrile?
2-Cyano-4-chloropyridine, 4-chloro-2-cyanopyridine, and 4-chloropyridine-formonitrile refer to the same substance. The synthesis methods are as follows:
First, 4-chloropyridine is used as the starting material. 4-chloropyridine and cyanide reagents, such as cuprous cyanide, are co-heated in suitable organic solvents and under specific reaction conditions, and cyano replaces the hydrogen atom on the pyridine ring to form the target product. During this process, the solvent needs to have good solubility to the reactants and products, and no side reactions with the reactants. The reaction temperature, time and the proportion of reactants have significant effects on the reaction yield.
Second, 2-amino-4-chloropyridine is used as the starting material. First, 2-amino-4-chloropyridine is diazotized to form a diazonium salt intermediate, and then interacts with cuprous cyanide or other cyanidation reagents. The diazonium group is replaced by cyanide, and finally 4-chloro-2-cyanopyridine is obtained. The diazotization reaction conditions are relatively harsh, and factors such as temperature and acidity need to be precisely controlled to prevent side reactions from occurring and affect the purity and yield of the product.
Third, 4-chloro-2-methylpyridine is used as the starting material. 4-Chloro-2-methylpyridine is oxidized to a cyanyl group in the presence of a specific catalyst and a suitable oxidant to obtain 4-chloro-2-cyanopyridine. In this method, the choice of catalyst and the regulation of oxidation conditions are crucial to the reaction process and product formation. Improper conditions can easily lead to excessive oxidation or incomplete oxidation.
Different synthesis methods have their own advantages and disadvantages. In practical application, the most suitable synthesis path should be selected based on the availability of raw materials, reaction conditions, cost, and product purity requirements.
2-Cyano-4-chloropyridine, 4-Chloro-2-cyanopyridine, 4-Chloropicolinonitrile What are the precautions in storage and transportation
2-Cyano-4-chloropyridine, 4-chloro-2-cyanopyridine, and 4-chloropicolinitrile are different names for the same substance. When storing and transporting, pay attention to the following things:
First, the storage place must be dry and well ventilated. If this substance encounters moisture or due to water vapor erosion, its properties will change, which will affect its quality. Therefore, in the warehouse, there should be moisture-proof facilities and smooth ventilation to prevent the accumulation of harmful gases.
Second, temperature control is crucial. Should avoid hot topics, in order to prevent the temperature is too high and the chemical reaction, or cause the risk of combustion, explosion. Generally speaking, it should be stored in a cool place, the temperature should not exceed 30 ℃.
Third, this substance may have a certain toxicity and irritation, in the handling process, the operator must wear protective equipment, such as gloves, masks, goggles, etc., to avoid contact with the skin, respiratory tract, etc., causing damage to the body.
Fourth, when storing, should not be co-located with oxidants, acids, alkalis, etc. Due to contact with it, it is easy to cause violent chemical reactions, and dangerous. Must be classified and stored at a certain distance, with obvious signs.
Fifth, when transporting, ensure that the container is intact and there is no risk of leakage. Vehicles also need to run smoothly to avoid bumps and vibrations to prevent package damage. And transportation vehicles must have corresponding warning signs and follow the specified route.
Sixth, the storage place should be equipped with corresponding emergency treatment equipment and suitable containment materials. If there is a leak, it can be dealt with immediately to reduce the harm.
2-Cyano-4-chloropyridine, 4-Chloro-2-cyanopyridine, 4-Chloropicolinonitrile market price
Guanfu 2 - Cyano - 4 - chloropyridine, 4 - Chloro - 2 - cyanopyridine, 4 - Chloropicolinonitrile these three are the names of chemical substances, but its market price is difficult to sum up.
covers the market price, often affected by many factors. First, the cost of raw materials. If the raw materials required for its preparation are scarce, or the collection and refining process is complicated and expensive, the product price will be high. Second, the production process. The exquisite and efficient production process can reduce costs and increase efficiency, making the product price competitive in the market; on the contrary, if the process is crude and inefficient, the cost will increase, and the price will also rise. Third, the supply and demand of the market. If the market demand for the substance is strong, but the supply is limited, as the so-called "rare things are expensive", the price will rise; if the supply exceeds the demand, the price will inevitably fall.
Furthermore, different suppliers, due to their own operating costs and business strategies, the quoted prices will be very different. And the market conditions change rapidly, and the prices fluctuate from time to time.
Therefore, in order to know the exact market prices of these three substances, it is necessary to search for market information, consult many suppliers, and comprehensively consider all factors to obtain more accurate price information. It is absolutely impossible to judge the price by name alone.