2-Cyano-3,5-dichloropyridine

2-Cyano-3,5-dichloropyridine is one of the organic compounds. It has a wide range of main uses in the field of pesticides and is often a key intermediate for the creation of new insecticides and fungicides. Due to the structure of the pyridine ring, the compound has unique activity, and the presence of cyano and chlorine atoms can significantly enhance its biological activity and stability. Taking the creation of insecticides as an example, 2-cyano-3,5-dichloropyridine can be converted into compounds with high insecticidal properties through specific chemical reactions, which can interfere with the nervous system or physiological and metabolic processes of pests to achieve insecticidal effect.
In the field of medicine, it is also an important raw material for the synthesis of many drugs. The properties of the pyridine ring and its substituents make it play a key role in the design of drug molecules. It can be modified to make the synthesized drug show high affinity and specificity for specific disease targets, such as for some cancer or inflammation-related targets, to help develop new therapeutic drugs.
In addition, in the field of materials science, 2-cyano-3,5-dichloropyridine may also play a role. After chemical transformation, materials with special properties, such as photoelectric materials, can be prepared. Its molecular structure properties may endow materials with unique optical and electrical properties, which have potential application value in organic light emitting diodes, solar cells and other fields.
Overall, 2-cyano-3,5-dichloropyridine has important uses in pesticides, medicine, materials science and other fields due to its unique structure and chemical properties, and is an important cornerstone for the creation of many chemicals and the development of new materials.

2-Cyano-3,5-dichloropyridine, this is an organic compound. Its physical properties are unique and are the basis for many chemical applications.
Looking at its properties, under room temperature and pressure, it is mostly white to light yellow crystalline powder. This form is easy to store and use, and it is easy to control in various chemical operations. Its melting point is quite critical, between 108-112 ° C. The characteristics of the melting point are of great significance in the identification, separation and purification of substances. With the determination of the melting point, the purity can be judged, and when separating the mixture, the separation of substances can be effectively achieved according to the difference in melting point.
Solubility is also an important physical property. 2-Cyano-3,5-dichloropyridine is slightly soluble in water, but soluble in common organic solvents such as ethanol, acetone, and dichloromethane. Such solubility characteristics determine its tendency to select solvents for chemical reactions. In organic synthesis reactions, selecting suitable organic solvents can promote sufficient contact of the reactants and improve the reaction rate and yield. In some reactions that need to be carried out in a homogeneous system, choose an organic solvent that can dissolve the substance to make the reaction proceed smoothly.
Furthermore, its stability cannot be ignored. Under conventional storage conditions, 2-cyano-3,5-dichloropyridine is relatively stable. In case of open flames, hot topics or contact with strong oxidants, there is a potential danger. This stability feature requires strict compliance with safety regulations during storage and transportation to ensure a suitable environment, away from fire sources, heat sources and strong oxidants, in order to prevent accidents.
In summary, the physical properties of 2-cyano-3,5-dichloropyridine, such as properties, melting point, solubility and stability, play an important role in chemical research, industrial production and other fields, profoundly affecting various operations and applications related to it.

2-Cyano-3,5-dichloropyridine, this is an organic compound with unique chemical properties. Its appearance is usually white to off-white crystalline powder, which is relatively stable at room temperature and pressure.
When it comes to solubility, it exhibits good solubility in organic solvents such as dichloromethane, chloroform, and N, N-dimethylformamide, which is convenient for acting as a reaction substrate or intermediate in organic synthesis operations. In water, its solubility is poor. Due to the presence of cyano and chlorine atoms in the molecular structure, the polarity does not match that of water.
2-Cyano-3,5-dichloropyridine is chemically active, due to the influence of cyanyl and chlorine atoms on the pyridine ring. As a strong electron-absorbing group, the cyanyl group reduces the electron cloud density of the pyridine ring, making it more susceptible to nucleophilic attack. Chlorine atoms can undergo substitution reactions under appropriate conditions. In nucleophilic substitution reactions, hydroxyl, amino and other nucleophilic reagents can replace chlorine atoms, and then form new chemical bonds to achieve the synthesis of diverse organic compounds.
Under acidic or alkaline environments, the stability of 2-cyano-3,5-dichloropyridine will change. In strong alkali conditions, the cyano group may be hydrolyzed to form derivatives such as carboxyl or amide groups; in strong acid environments, the pyridine ring may be protonated, thus affecting its reactivity and selectivity.
When heated, 2-cyano-3,5-dichloropyridine needs to pay attention to its stability. Although it will not decompose easily, high temperature may cause it to undergo rearrangement reactions or side reactions with other impurities. Therefore, during storage and use, it is necessary to control the temperature conditions to ensure its chemical stability and avoid quality changes due to temperature factors.

There are several methods for the synthesis of 2-cyano-3,5-dichloropyridine. One method can also start from 3,5-dichloropyridine and make it react with cyanide reagents such as cuprous cyanide under suitable reaction conditions, such as in a specific organic solvent. It is heated and catalyzed to cause a cyanyl substitution reaction. This is achieved by the mechanism of nucleophilic substitution, so that the target product can be prepared.
Another method, or a suitable pyridine derivative, can introduce a chlorine atom at a specific position first, and then a cyanyl group. For example, pyridine is used as the starting material, and chlorine atoms are introduced into the 3,5 positions through a halogenation reaction. Suitable halogenation reagents and reaction conditions can be selected for this halogenation reaction to achieve dichloro-substituted pyridine derivatives. Then, the derivative is cyanized, or cyanide reagents are used in a suitable reaction environment to achieve the introduction of cyano groups, resulting in 2-cyano-3,5-dichloropyridine.
Furthermore, the reaction path involving organometallic reagents can be used. If the organometallic intermediate containing the pyridine structure is prepared first, and then reacts with the cyanide source and chlorine-containing reagents, it is also expected to synthesize this compound through reasonable reaction design and control of conditions. Among them, the selection and preparation of organometallic reagents, as well as the fine regulation of the reaction conditions at each step, are the key factors, which are related to the success or failure of the reaction and the purity and yield of the product.

I have not seen the exact price range of 2-cyano-3,5-dichloropyridine on the market. However, in order to approximate it, many reasons need to be considered.
First, the preparation of this compound is difficult and easy. If the preparation method is complicated, the materials used are rare, or harsh reaction conditions are required, such as precise temperature control, specific catalysts, etc., the manufacturing cost will be high, and the price will also increase.
Second, the market supply and demand situation. If many industries, such as medicine, pesticide R & D and manufacturing, have strong demand for it, but the supply is limited, the price will increase; conversely, if the demand is weak and the supply is abundant, the price may drop.
Third, the scale of production also has an impact. Large-scale production can often reduce the unit cost through economies of scale, and the price may be relatively easy; small-scale production is difficult to reduce the cost and the price is higher.
Fourth, the price of raw materials fluctuates. If the price of 2-cyano-3,5-dichloropyridine raw materials is unstable, it often fluctuates due to market supply and demand, production yield, policy changes, etc., which will lead to fluctuations in the price of finished products.
Also considering the price trend of similar compounds in the past, in the field of fine chemicals, such compounds with specific structures and uses, if the preparation difficulty is moderate, when small-scale transactions, the price per gram may be around tens of yuan to hundreds of yuan; if large-scale purchases, depending on the scale, the price per kilogram may range from several thousand yuan to ten thousand yuan. However, this is only speculation. The actual price should be subject to real-time quotations in the market. It is advisable to consult chemical raw material suppliers, trading platforms or industry veterans in detail to obtain the exact price range.