2-Chloropyridine-5-acetic acid

2-Chloropyridine-5-acetic acid, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. The synthesis of many drugs relies on this as a starting material. Through specific chemical reactions, it can be transformed into complex molecular structures with specific pharmacological activities, such as the development and preparation of antibacterial drugs, antiviral drugs, etc., or useful.
In the field of pesticide chemistry, it also plays an important role. It can become the basic material for the synthesis of new pesticides, endowing pesticides with functions such as weeding, insecticide, and sterilization, helping to improve crop yield and quality, and escorting agricultural production.
In the field of materials science, 2-chloropyridine-5-acetic acid may participate in the synthesis process of some special materials. By reacting with other compounds, the properties of the material can be changed, such as improving the stability and solubility of the material, etc., thereby meeting the needs of special materials in different fields.
This compound has unique reactivity and role in many fields due to its unique chemical structure. It is an indispensable and important substance in the modern chemical synthesis industry and plays a pivotal role in promoting the development process of medicine, pesticides, materials and other industries.

2-Chloropyridine-5-acetic acid, this is an organic compound. Its physical properties are quite important and are related to many chemical applications.
Looking at its properties, under normal temperature and pressure, 2-chloropyridine-5-acetic acid often appears as a white to light yellow solid. This morphology is stable and easy to store and transport. Its color characteristics can help to identify preliminarily, providing an intuitive basis for the identification of substances in experiments and production processes.
When it comes to the melting point, the melting point of this compound is about [X] ° C. The melting point is a key physical property, and the purity of the substance can be judged by measuring the melting point. If the melting point agrees with the theoretical value, it indicates high purity; if the melting point range widens or deviates from the theoretical value, it indicates that it may contain impurities.
In terms of solubility, 2-chloropyridine-5-acetic acid is slightly soluble in water. This property determines its reactivity and distribution in aqueous systems. However, it is soluble in some organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), etc. This difference in solubility provides an important reference for its separation, purification and solvent selection in organic synthesis reactions. Good solubility in dichloromethane makes it easy to act as a reactant or intermediate in some reactions that require the participation of organic solvents. The solubility of DMF makes it possible to better disperse and react with 2-chloropyridine-5-acetic acid in some reactions that require polar aprotic solvents.
In addition, its density also has certain significance. Although the exact density value varies depending on the measurement conditions, it is roughly within a certain range. Density information is indispensable in chemical production or experimental operations such as solution preparation and material balance. It helps to accurately control the proportion of materials in the reaction system and ensure the smooth progress of the reaction.
In conclusion, the physical properties of 2-chloropyridine-5-acetic acid, whether it is its appearance, melting point, solubility or density, play a crucial role in its research, production and application in the field of chemistry.

The chemical synthesis method of 2-chloropyridine-5-acetic acid, although the method of synthesis of this substance is not contained in the ancient book Tiangong Kaiwu, it can be described according to the current chemical principles and common synthesis ideas.
2-chloropyridine is often used as the starting material. First, 2-chloropyridine and a suitable halogenated alkane are alkylated under the action of a strong base, and the corresponding substituent is introduced at the 5th position of the pyridine ring to form a 5-substituted-2-chloropyridine derivative. This process requires strict control of the reaction conditions, such as the amount of base, reaction temperature and time, to ensure the selectivity and yield of the reaction.
Then, the obtained 5-substituted-2-chloropyridine derivatives are hydrolyzed to convert the 5-substituted group into a carboxyl group. The reagents and conditions used for hydrolysis vary depending on the nature of the 5-substituted group. If it is an ester group, it can be hydrolyzed by an acid or base; if it is a cyano group, it can be hydrolyzed to form a carboxyl group under acidic or basic conditions.
Another idea can be started from 2-chloro-5-methylpyridine. The methyl group is first oxidized to a carboxyl group. The commonly used oxidizing agents are potassium permanganate, potassium dichromate, etc. This oxidation process requires attention to the control of the reaction conditions to avoid excessive oxidation of the pyridine ring. After the oxidation is completed, 2-chloropyridine-5-acetic acid is obtained.
During the synthesis process, the product needs to be separated and purified at each step. Common methods include distillation, extraction, column chromatography, etc., to ensure the purity of the product, and then obtain high-purity 2-chloropyridine-5-acetic acid.

The price of 2-chloropyridine-5-acetic acid in the market is difficult to determine. Its price often varies due to various reasons, such as supply and demand conditions, differences in manufacturing techniques, differences in quality and the rise and fall of the city.
Looking at the past, in the chemical industry cities, the price range of this kind of fine chemical products is very wide. If the market is prosperous and the supply is limited, its price may rise; on the contrary, if the supply exceeds the demand, the price may be depressed.
In the past, those with high quality and high purity may cost hundreds of yuan per kilogram, while those with ordinary quality may cost hundreds of yuan per kilogram or less. However, this is only a rough estimate, and the actual price depends on the current market conditions, the amount purchased, and the seller's pricing policy.
If the buyer wants to know the exact price, he should consult the merchant of chemical raw materials, or visit the platform of chemical trading, so that he can get the real price in the near future.

2-Chloropyridine-5-acetic acid should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. This substance has a certain chemical activity, and when heated or damp, it is afraid of chemical reactions and causes quality changes.
The storage device must be corrosion-resistant and well-sealed to prevent contact with external substances and maintain its chemical stability. Due to the structure of chlorine and pyridine, it is sensitive to air and moisture. If the container is not well sealed, it is easy to interact with water vapor and oxygen in the air to deteriorate the substance.
And should be stored separately from oxidants, reducing agents, acids, bases, etc., and must not be mixed. Due to its chemical properties, it encounters with the above substances, or causes violent reactions, resulting in safety accidents.
Storage areas need to be prepared with suitable materials for containing and handling leaks. If there is a leak, it can be controlled in time to avoid polluting the environment and prevent the spread of harmful substances. Daily storage environment temperature and humidity need to be closely monitored and regulated. The temperature should be maintained below [X] ° C, and the relative humidity should be within [X]% to ensure stable storage of 2-chloropyridine-5-acetic acid, reduce the risk of deterioration, and ensure its quality and performance.