2 Chloropyridine 4 Carbaldehyde
pyridine pyrrole pyrazine piperidine piperazine

2-Chloropyridine-4-Carbaldehyde

    Specifications

    HS Code

    876586

    Chemical Formula C6H4ClNO
    Molecular Weight 141.55
    Appearance Yellow to light brown solid
    Melting Point 34 - 36 °C
    Boiling Point 229 - 230 °C
    Density 1.329 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Flash Point 92.5 °C
    Pungent Odor Yes

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    General Information
    Where to Buy 2-Chloropyridine-4-Carbaldehyde in China?
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    Frequently Asked Questions

    As a leading 2-Chloropyridine-4-Carbaldehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Chloropyridine-4-Carbaldehyde?
    2-Chloropyridine-4-formaldehyde is a key compound in the field of organic synthesis. Its main uses involve a wide range of aspects.
    In the field of drug synthesis, it is often an important intermediate. Drug research and development is related to human health and well-being, and the construction of many active compounds often depends on this substance. For example, in the synthesis of some heterocyclic drugs with specific pharmacological activities, 2-chloropyridine-4-formaldehyde can participate in key reaction steps. By ingeniously reacting with other reagents, the complex structure of drug molecules is gradually built, laying the foundation for the creation of new drugs.
    In the field of materials science, it also has extraordinary performance. With the rapid development of science and technology, the demand for new materials is increasing day by day. 2-chloropyridine-4-formaldehyde can be used as a raw material to participate in the preparation of functional materials. For example, in the synthesis of some photoelectric materials, its unique chemical structure endows the material with specific optical and electrical properties, showing potential application value in cutting-edge fields such as Light Emitting Diode and solar cells.
    In addition, it also plays an important role in the field of fine chemicals. The production of fine chemicals pursues high purity and specific functionality. 2-chloropyridine-4-formaldehyde can be used to synthesize special dyes, fragrances and other fine chemicals. Taking dye synthesis as an example, through the modification and derivatization of its structure, dyes with unique color and dyeing properties can be prepared to meet the diverse needs of different industries for color.
    In summary, 2-chloropyridine-4-formaldehyde plays an indispensable role in many fields such as drugs, materials, and fine chemicals due to its unique chemical properties, promoting technological progress and innovation in various fields.
    What are the physical properties of 2-Chloropyridine-4-Carbaldehyde?
    2-Chloropyridine-4-formaldehyde is a kind of organic compound. Its physical properties are quite critical and are listed as follows:
    Under normal temperature and pressure, 2-chloropyridine-4-formaldehyde is in a yellowish to yellow solid state. This color state is quite significant for the identification and preliminary recognition of this substance.
    When it comes to the melting point, it is about 58-62 ° C. The melting point is the inherent characteristic of the substance. At this temperature, the compound gradually melts from a solid state to a liquid state. This value is of great significance for its purification and phase transition research.
    The boiling point is about 239.5 ° C under certain conditions. The boiling point reflects the energy and conditions required for the substance to change from liquid to gaseous state, which is extremely important for its separation, purification and reaction conditions.
    As for solubility, 2-chloropyridine-4-formaldehyde is slightly soluble in water. Water is a common solvent, and this solubility implies that it interacts with water molecules to a limited extent. However, it has good solubility in common organic solvents such as ethanol, dichloromethane, and ether. Good solubility in organic solvents facilitates its operation in organic synthesis reactions, and many reactions can be carried out smoothly in these solvent systems.
    In addition, the density of 2-chloropyridine-4-formaldehyde cannot be ignored. Although the exact value varies slightly according to specific conditions, its density characteristics affect its distribution and mass transfer process in the reaction system. It is necessary to consider in chemical production and experimental operation.
    And because of the existence of specific functional groups in its molecular structure, the stability of 2-chloropyridine-4-formaldehyde in air has a certain limit, or it may deteriorate due to oxidation and other factors. Therefore, it is necessary to pay attention to environmental conditions when storing. It is usually recommended to place it in a cool, dry and well-ventilated place to prevent its physical properties from changing due to environmental influences and ensure its quality and efficiency.
    What are 2-Chloropyridine-4-Carbaldehyde synthesis methods?
    To prepare 2-chloropyridine-4-formaldehyde, there are many methods, and the following are briefly described.
    First, it can be started from a pyridine compound. Based on a pyridine derivative, under specific conditions, chlorine atoms are first introduced. This requires selecting a suitable chlorination reagent, such as a chlorine-containing halogenating agent, and controlling the reaction temperature, time and proportion of the reactants. Next, after specific steps, an aldehyde reaction occurs at a specific location. To be aldehyde-ylated, an aldehyde-based reagent with specific activity can often be used, and with the help of a catalyst, the aldehyde group at the target location can be introduced to obtain 2-chloropyridine-4-formaldehyde.
    Second, the design of the organic synthesis route can also be used to start from the basic organic raw materials and construct the pyridine ring through multi-step reactions. First, the pyridine skeleton is initially built with appropriate carbon and nitrogen-containing raw materials through condensation, cyclization and other reactions. In the process of constructing the pyridine ring, the reaction sequence and conditions are cleverly planned, so that the chlorine atom and the aldehyde group are connected according to the expected position. Although this path is a little complicated, if the design is subtle, the target product can be accurately obtained.
    Third, there is still an idea to use the compound containing the pyridine structure and some functional groups as the starting material. First, the functional group is converted to convert the non-target functional group into the desired chlorine atom and aldehyde group. This requires familiarity with various functional group conversion reactions, selection of appropriate reagents and conditions, and gradual modification to finally obtain 2-chloropyridine-4-formaldehyde.
    Synthetic methods have their own advantages and disadvantages, and need to be based on actual needs, raw material availability, cost considerations, and the operability of reaction conditions.
    2-Chloropyridine-4-Carbaldehyde What are the precautions during storage and transportation?
    2-Chloropyridine-4-formaldehyde is an important intermediate in organic synthesis. During storage and transportation, many matters need to be paid attention to in order to ensure its quality and safety.
    First of all, this compound should be stored in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature and humid environment are prone to deterioration. Therefore, the warehouse temperature should be controlled within a suitable range, do not allow direct sunlight, and moisture-proof measures must be complete to prevent it from interacting with water vapor. Furthermore, it should be stored separately from oxidants, acids, bases, etc. Due to its active chemical properties, it is easy to react with the above substances and cause danger. When storing, it is also necessary to make a good logo, indicating the name, specification, date and other key information for easy management and traceability.
    As for transportation, the packaging must be tight and reliable to ensure that there is no leakage in the case of bumps, vibrations, etc. The selection of appropriate packaging materials can effectively resist external shocks. During transportation, the temperature should be strictly controlled to avoid large fluctuations in temperature. And the transportation vehicle must be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment, just in case. Transportation personnel should also be familiar with its characteristics and emergency treatment methods. In case of emergencies, they can respond quickly and properly to reduce losses and hazards. Overall, the storage and transportation of 2-chloropyridine-4-formaldehyde requires rigorous operation and compliance with relevant norms and requirements to ensure the safety and stability of the entire process.
    What is the market price range for 2-Chloropyridine-4-Carbaldehyde?
    The market price range of 2-chloropyridine-4-formaldehyde is difficult to determine for many reasons. This compound has a wide range of uses and is often used as a key intermediate in the field of pharmaceutical synthesis. It can be used to create antibacterial and anti-inflammatory drugs. It also has a place in pesticide synthesis, helping to prepare high-efficiency and low-toxicity pesticides.
    In terms of its market price, it is affected by the cost of raw materials. If the price of raw materials for preparing this compound fluctuates, the cost will also fluctuate, which will affect the selling price. Furthermore, the complexity of the production process has a deep impact on the price. If the process is cumbersome, requires multiple reactions, harsh conditions and high-purity raw materials, the cost will be high and the price will rise.
    The market supply and demand situation is the key factor. If the pharmaceutical, pesticide and other industries have strong demand for it, but the supply is limited, the price will rise; conversely, if the market is saturated and the supply is sufficient, the price may decline. In addition, the manufacturer's brand, product quality and packaging specifications will also cause price differences.
    Generally speaking, in the chemical raw material market, the price of 2-chloropyridine-4-formaldehyde may range from tens of thousands to hundreds of thousands of yuan per ton due to different purity and packaging specifications. However, this is only a general range. The actual price needs to be consulted with chemical product suppliers in detail, combined with the current market conditions and specific procurement needs, in order to obtain accurate quotations.