2 Chloropyridine 3 4 Diamine
pyridine pyrrole pyrazine piperidine piperazine

2-chloropyridine-3,4-diamine

    Specifications

    HS Code

    786275

    Chemical Formula C5H6ClN3
    Molecular Weight 143.57
    Appearance Solid (usually white or off - white powder)
    Melting Point Typically in a certain temperature range (data needs more precise literature search)
    Boiling Point Requires specific experimental determination, difficult to predict without data
    Solubility In Water Low solubility, organic solvents may have better solubility
    Odor May have a faint, characteristic amine - like odor
    Density Value needs experimental measurement or specific literature data
    Pka Values related to its acidic - basic properties, specific data from literature
    Stability Stable under normal conditions, may react with strong oxidizing agents

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    Frequently Asked Questions

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    What are the chemical properties of 2-chloropyridine-3,4-diamine?
    2-Chloropyridine-3,4-diamine is a kind of organic compound. It has specific chemical properties. Looking at its structure, the chlorine atom is connected to the pyridine ring, and the specific position on the ring is diamine.
    This compound has its characteristics in various fields of chemistry. In terms of physical properties, under normal temperature and pressure, or as a solid, the exact properties also depend on specific purity and environmental factors. The values of its melting point and boiling point are determined by the intermolecular forces and structural characteristics. Intermolecular hydrogen bonds, van der Waals forces and other factors cause it to have a specific phase transition temperature.
    In terms of chemical properties, chlorine atoms have electron-absorbing properties, which can affect the distribution of electron clouds in pyridine rings and change the density of electron clouds on the rings. This makes it unique in nucleophilic substitution reactions. The existence of amino groups makes it alkaline and can neutralize with acids to form corresponding salts. And amino groups can participate in a variety of organic reactions, such as acylation reactions, alkylation reactions, etc. Under suitable conditions, it can react with acid chloride, acid anhydride, etc. to form amide derivatives; react with halogenated hydrocarbons to obtain alkylation products.
    2-chloropyridine-3,4-diamine has potential applications in pharmaceutical chemistry, materials science and other fields due to its special chemical structure and properties. In drug development, compounds with specific biological activities may be designed based on their structure as drug precursors. In materials science, it may be able to participate in the synthesis of polymer materials with special properties.
    What are the common uses of 2-chloropyridine-3,4-diamine?
    2-Chloropyridine-3,4-diamine has a wide range of uses and is commonly found in various fields.
    In the field of medicinal chemistry, this compound is often a key intermediate for the synthesis of drugs. Due to its special chemical structure, it can participate in a variety of chemical reactions and help form molecules with specific biological activities. For example, in the creation of some antibacterial and antiviral drugs, 2-chloropyridine-3,4-diamine can be used as a starting material. After a series of reactions, specific functional groups are introduced to build complex drug molecular structures, which are important for resisting germ invasion and healing diseases.
    In materials science, it also has its uses. Polymer materials with specific properties can be obtained by polymerizing with other monomers. Or give the material good electrical conductivity, optical properties, etc., which has potential application value in electronic devices, optoelectronic devices and other fields. For example, it is applied to the research and development of organic Light Emitting Diode (OLED) materials, which is expected to improve the luminous efficiency and stability of the device.
    Furthermore, in the field of agricultural chemistry, it can be used as a raw material for the synthesis of new pesticides. After rational molecular design and modification, the synthesis of pesticides with efficient killing effect on pests, environmental friendliness, and low toxicity to non-target organisms can help agricultural pest control, ensure crop yield and quality, and maintain sustainable agricultural development.
    In conclusion, 2-chloropyridine-3,4-diamine plays an important role in many fields such as medicine, materials, and agriculture due to its unique chemical properties, providing key support for the development of many industries.
    What is the preparation method of 2-chloropyridine-3,4-diamine?
    The preparation of 2-chloropyridine-3,4-diamine is an important technique in the field of organic synthesis. Its preparation often follows several paths.
    First, it can be started from suitable pyridine derivatives. For example, using 2-chloropyridine-3-nitro-4-halide as raw material, the nitro group is first reduced to amino group with an appropriate reducing agent under suitable reaction conditions. Commonly used reducing agents such as iron filings and hydrochloric acid are combined. This is a classic reduction system. In an environment heated and stirred, nitro groups are gradually converted into amino groups. The reaction mechanism is that the interaction of iron filings with hydrochloric acid produces new hydrogen, and the new hydrogen reduces the nitro group. < Br >
    Second, 2-chloro-3,4-dihalopyridine can also be used as the starting material. First react with an ammonia source, such as liquid ammonia or ammonia water, under high temperature and pressure conditions. In this reaction, the halogen atom is gradually replaced by an amino group. Ammonia's nucleophilicity prompts it to attack the carbon atom connected to the halogen atom, the halogen atom leaves, and the amino group joins, thus achieving the preparation of the target product. In this process, the reaction temperature and pressure have a great influence on the reaction process and product yield.
    Or, the coupling reaction catalyzed by transition metals can be used. Nucleophilic reagents containing amino groups are selected, and 2-chloropyridine derivatives are used in the presence of transition metal catalysts, such as palladium catalysts, to achieve the introduction of amino groups. The reaction requires suitable ligands to stabilize the metal catalyst and enhance its catalytic activity. Such methods require more harsh reaction conditions, but they can efficiently and accurately construct the target molecular structure.
    All preparation methods have advantages and disadvantages. In actual operation, it is necessary to consider the availability of raw materials, the controllability of reaction conditions, and the purity and yield of the product.
    What are the precautions for 2-chloropyridine-3,4-diamine during storage and transportation?
    2-Chloropyridine-3,4-diamine is a chemical substance. During storage and transportation, there are many matters to be paid attention to.
    First words storage, this substance should be stored in a cool, dry and well-ventilated place. Because it may be quite sensitive to temperature and humidity, if it is in a high temperature and humid environment, it may cause its properties to change or cause chemical reactions. For example, high temperature can promote its decomposition, and humid gas may cause it to absorb moisture and deteriorate, which will damage its quality and utility. Therefore, where it is stored, the temperature should be controlled within a suitable range, and the humidity should also be maintained within a reasonable range.
    Furthermore, this substance should be stored separately from oxidants, acids, bases, etc. This is because the chemical properties of 2-chloropyridine-3,4-diamine are active, and contact with them can easily cause violent chemical reactions, or even risk fire and explosion. If the oxidizing agent has strong oxidizing properties, it will meet with 2-chloropyridine-3,4-diamine, or cause oxidation reaction, resulting in sudden heat generation.
    As for transportation, it is necessary to ensure that the packaging is intact. If the packaging is damaged, 2-chloropyridine-3,4-diamine may leak out, which not only pollutes the environment, but also poses a threat to the safety of transporters. At the same time, vibration, impact and friction should be avoided during transportation. Such external forces may cause damage to the packaging or cause internal chemical reactions.
    In addition, transportation vehicles should be equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. If an accident occurs during transportation, such as a leakage accident, timely measures can be taken to reduce the harm. And transportation personnel should be professionally trained and familiar with the characteristics and emergency treatment methods of 2-chloropyridine-3,4-diamine, so as to ensure their safety during storage and transportation and avoid dangerous accidents.
    What is the market outlook for 2-chloropyridine-3,4-diamine?
    2-Chloropyridine-3,4-diamine is one of the organic compounds. Its market prospects can be viewed from multiple perspectives.
    From the field of medicine, this compound has great potential. Due to its unique structure, or can be used as a pharmaceutical intermediate, it is expected to be used in the creation of new drugs. Today's pharmaceutical research and development is constantly seeking new molecular entities to solve various diseases and problems. The structural characteristics of 2-chloropyridine-3,4-diamine may enable it to participate in the drug synthesis path, providing an opportunity for the development of new anti-disease drugs. For example, in the exploration of anti-tumor drugs, it may be chemically modified and integrated into the molecular structure of the drug to help the drug accurately act on the target of tumor cells in order to achieve better therapeutic effect.
    In the field of pesticides, it also has potential. Today's agricultural production has an increasing demand for high-efficiency, low-toxicity and environmentally friendly pesticides. 2-chloropyridine-3,4-diamine can be rationally designed and modified, or can be used as a pesticide active ingredient. It has the ability to kill bacteria, insects or weeds, and compared with traditional pesticides, or has advantages in environmental residues, biotoxicity, etc., in line with the general trend of green agriculture development.
    Looking at the field of materials science again. With the advance of science and technology, the demand for special performance materials is increasing. 2-Chloropyridine-3,4-diamine can participate in the material synthesis reaction by virtue of its chemical activity. Or it is a key monomer for the synthesis of special polymer materials, endowing the materials with excellent thermal stability, mechanical properties or optical properties, etc., and finding a place in high-end fields such as electronics and aerospace.
    However, its market development also faces various challenges. The synthesis process needs to be optimized to reduce costs and increase yield. And when it is introduced to the market, it must pass strict safety and environmental assessments to prove that it is safe for ecology and personal safety.
    To sum up, the market prospect of 2-chloropyridine-3,4-diamine is promising, but to fully explore its potential, it still needs the cooperation of scientific research, production and other parties to solve the problems and promote its wide application in various fields.