2-(Chloromethyl)pyridine hydrochloride

2-%28Chloromethyl%29pyridine+hydrochloride is 2- (chloromethyl) pyridine hydrochloride. The physical properties of this substance are as follows:
It is white to off-white crystalline powder at room temperature, and it looks shiny. It has a certain melting point, about 142-146 ° C. This characteristic can be used for identification and purity judgment. In terms of solubility, it is easily soluble in water. Because there are parts in the molecular structure that can form hydrogen bonds with water molecules, it can be well dispersed in water. It is also easily soluble in common polar organic solvents, such as methanol, ethanol, etc., because of its similar miscibility with polar organic solvents.
In terms of stability, 2 - (chloromethyl) pyridine hydrochloride can be stored stably in a dry and cool place under conventional storage conditions. However, in case of high temperature, high humidity environment, or contact with strong oxidants, strong bases, etc., its structure may change. Because of its chloromethyl and pyridine ring structure, chloromethyl has a certain activity, and is prone to nucleophilic substitution and other reactions under alkaline conditions, resulting in structural changes.
In addition, this substance is relatively stable in the air and is not easy to evaporate. Its smell is weak, but it still needs to be paid attention to when operating, because even if the chemical substance has a light smell, it may also be potentially harmful to the human body. In conclusion, understanding the physical properties of 2 - (chloromethyl) pyridine hydrochloride is of great significance for its storage, use and control of related chemical reactions.

To prepare 2 - (chloromethyl) pyridine hydrochloride, there are three methods.
First, pyridine is used as a group and obtained by chloromethylation. Pyridine is co-placed with paraformaldehyde and hydrogen chloride in a suitable solvent, such as dichloroethane, and heated to promote the reaction. In this case, paraformaldehyde releases formaldehyde, and is co-used as a chloromethyl source with hydrogen chloride. After the reaction is completed, the product can be obtained by a suitable method such as distillation to remove the solvent, and then purified by recrystallization.
Second, it is prepared by the reaction of 2-hydroxymethylpyridine with a chlorinating agent. If thionyl chloride is used as the chlorinating agent, 2-hydroxymethylpyridine is co-mixed with it in the reaction bottle. At an appropriate temperature, thionyl chloride interacts with hydroxyl groups to obtain 2- (chloromethyl) pyridine by chlorination, and then forms a salt with hydrogen chloride. After the reaction, the excess chlorinating agent and by-product gas are removed first, and then the product is obtained by separation and purification.
Third, 2-methylpyridine is formed by oxidation and chlorination. First, oxidize 2-methylpyridine to 2-pyridinecarboxylic acid with a suitable oxidant, such as potassium permanganate or hydrogen peroxide, and then reduce it to 2-hydroxymethylpyridine, and then replace it with chlorination agent as mentioned above, and finally form a salt. There are many steps in this way, but the raw materials are easy to obtain, and it is also feasible to optimize. Each method has its own advantages and disadvantages, and the appropriate method must be selected according to the actual situation, such as the availability of raw materials, cost, product purity, etc.

2-%28Chloromethyl%29pyridine+hydrochloride is 2 - (chloromethyl) pyridine hydrochloride, which is used in medicine, pesticides, materials and other fields.
In the field of medicine, it is a key organic synthesis intermediate. Through delicate chemical reactions, it can be skillfully converted into compounds with unique structures. These compounds have significant biological activity and are like a shining cornerstone in the long journey of drug development. In the synthesis of many innovative drugs for the treatment of cardiovascular diseases and nervous system diseases, 2 - (chloromethyl) pyridine hydrochloride plays an indispensable role and contributes to the vigorous development of human health.
The field of pesticides is also where it shows its talents. With this as the starting material, through a series of rigorous chemical operations, highly efficient and low-toxic pesticide products can be carefully prepared. These pesticides are like loyal guardians of farmland, with strong inhibition and killing ability to pests, while minimizing environmental harm, escorting the robust growth of crops, helping agricultural harvests, and ensuring food security.
The field of materials science cannot ignore its existence either. In the complex process of synthesizing special functional materials, 2- (chloromethyl) pyridine hydrochloride participates in the construction of novel molecular structures with its own unique chemical properties. These materials often have excellent properties, such as good electrical conductivity and excellent optical properties, which have shown broad application prospects in cutting-edge fields such as electronic devices and optical instruments, driving related fields to new heights.

2-%28Chloromethyl%29pyridine+hydrochloride is 2 - (chloromethyl) pyridine hydrochloride. The market price range of this product is difficult to determine. The price often changes for a variety of reasons.
First, the supply and demand relationship of the city is the main reason. If there are many people, the supply is small, the price will tend to rise; on the contrary, if the supply exceeds the demand, the price will fall. Second, the price of raw materials also has a great impact. The production of 2 - (chloromethyl) pyridine hydrochloride requires specific raw materials. If the price of raw materials rises, the price of finished products will also rise; if the price of raw materials falls, the price of finished products is also expected to fall. Third, the manufacturing cost cannot be ignored. Including the simplicity of the production process, the amount of energy consumption, and the high and low labor costs. The price is not low if the process is complicated, the energy consumption is high, and the labor cost is high. Fourth, the manufacturer's brand and product quality are also related to the price. Well-known manufacturers, those with excellent quality, often have high prices; unknown manufacturers, those with inferior quality, or low prices.
Looking at the past market, the price of 2 - (chloromethyl) pyridine hydrochloride fluctuates within a certain range. However, due to the above factors changing from time to time, it is difficult to determine the value. To know the exact market price, you can consult chemical product suppliers, check chemical trading platforms or market survey reports to get accurate prices in the near future.

2 - (chloromethyl) pyridine hydrochloride, this is a chemical substance. Its storage conditions are crucial and related to the characteristics and safety of this substance.
The cover should be stored in a cool place because of its special chemical properties. In a cool place, the temperature is low, which can slow down the rate of chemical change, and will not cause adverse reactions due to excessive temperature.
and must be kept dry, avoid humid places. Because moisture can easily cause this substance to get wet, or cause reactions such as hydrolysis, which will damage its quality.
Furthermore, it needs to be sealed and stored. If exposed to air, it is easy to interact with the components in the air, such as oxygen, carbon dioxide, etc., resulting in deterioration. < Br >
It should also be kept away from fire and heat sources. This substance may be flammable or easily decomposed by heat, and both fire and heat sources can cause its danger.
The storage place should also be separated from oxidants, acids, and bases. Due to its chemical activity, contact with them may cause violent reactions and endanger safety.
Therefore, the storage of 2- (chloromethyl) pyridine hydrochloride should be cool, dry, sealed, and kept away from fire sources and heat sources, and placed separately from other chemicals to ensure the stability and safety of this substance.