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What is the chemical structure of 2-chloro-N- [4- (1-cyanocyclopentyl) phenyl] -3-Pyridinecarboxamide?
This is the chemical structure analysis of 2-chloro-N- [4- (1-cyanocyclopentyl) phenyl] -3-pyridine formamide. This compound is composed of a pyridine ring, a benzene ring and a cyclopentyl group.
On the pyridine ring, the 2-position chlorine atom is substituted, and the 3-position is connected to the formamide group. In the formamide group, the carbonyl group is connected to the nitrogen atom, and the nitrogen atom is connected to the benzene ring. The 4-position of the
benzene ring is connected to the 1-cyanocyclopentyl group. In the 1-cyanocyclopentyl group, the cyclopentyl group is a The cyanyl group is connected by a triple bond between a carbon atom and a nitrogen atom.
Overall, this compound has a complex structure, and each group is connected to each other, giving it specific chemical properties and reactivity. The aromatic properties of pyridine rings and benzene rings, as well as functional groups such as chlorine atoms, cyano groups, and formamido groups, determine that it can participate in many chemical reactions, and may have important uses in organic synthesis, pharmaceutical chemistry, and other fields.
What are the main uses of 2-chloro-N- [4- (1-cyanocyclopentyl) phenyl] -3-Pyridinecarboxamide?
2-Chloro-N- [4- (1-cyanocyclopentyl) phenyl] -3-pyridineformamide is one of the organic compounds. Its main uses are quite extensive, and it is often the key intermediate for the creation of new drugs in the field of medicinal chemistry.
The compound has a unique chemical structure, which contains parts such as pyridineformamide, chlorine atom and cyanocyclopentylphenyl, giving it the potential to interact with specific targets in organisms. From the perspective of drug development, this structural property may enable it to exhibit highly selective binding ability to proteins, enzymes or receptors related to specific diseases.
For example, in the field of anti-cancer drug research and development, scientists may use its chemical modification and optimization to make the compound act precisely on the target of abnormal expression in cancer cells, inhibit the proliferation, migration and invasion of cancer cells, and achieve the purpose of treating cancer.
In the development of antimicrobial drugs, its structure may be combined with key metabolic enzymes or cell wall synthesis-related proteins in microorganisms to interfere with the normal physiological metabolism of microorganisms and play an antibacterial effect.
Furthermore, in the field of agricultural chemistry, it may also have potential applications. Or it can be used as a raw material for the creation of new pesticides, by interfering with the physiological activities of pests or pathogens, to achieve effective prevention and control of crop diseases and insect pests, and to ensure the yield and quality of crops. In conclusion, 2-chloro-N- [4- (1-cyanocyclopentyl) phenyl] -3-pyridineformamide has broad application prospects in the fields of medicine and agricultural chemistry due to its special chemical structure, providing an important material basis for research and innovation in related fields.
What are the synthesis methods of 2-chloro-N- [4- (1-cyanocyclopentyl) phenyl] -3-Pyridinecarboxamide?
The synthesis of 2-chloro-N- [4- (1-cyanocyclopentyl) phenyl] - 3-pyridine formamide is related to the delicate technology in the field of organic synthesis. There are several common routes for the synthesis of this compound.
First, pyridine is used as the starting material. Pyridine is first formylated at the 3-position, and the 3-position of pyridine can be introduced into the formyl group by suitable formylation reagents, such as under specific catalysts and reaction conditions. Subsequently, chlorine atoms are introduced into the 2-position of the pyridine ring. In this step, appropriate chlorination reagents are selected to control the reaction temperature, time and ratio of reactants to accurately realize the 2-chlorination reaction. At the same time, the 4- (1-cyanocyclopentyl) phenyl moiety is constructed. Starting from benzene, cyclopentyl groups are introduced into the 4-position of the phenyl ring through a series of steps such as Fu-gram reaction. Finally, the pyridine-containing structural fragments are connected to the 4- (1-cyanocyclopentyl) phenyl-containing fragments through amidation to form the target product. In the amidation reaction, a suitable condensing agent needs to be selected to ensure the efficient progress of the reaction.
Second, aniline derivatives can also be used as starting materials. First, the aniline is properly protected to avoid the interference of amino groups in subsequent reactions. Next, the pyridine ring is constructed through a series of reactions, such as using a suitable heterocyclic synthesis method to form a pyridine structure under specific conditions, and corresponding substituents are introduced at the 2-position and 3-position of the pyridine ring at the same time. On the other hand, the phenyl ring is modified to introduce a cyclopentyl group at the 4-position and further cyanylated to form a 4- (1-cyanocyclopentyl) phenyl structure. Finally, the amino protecting group is removed and the target compound is prepared by amidation reaction.
The precise control of the reaction conditions is the key to the synthesis of this compound. Temperature, pH, reaction time and other factors will have a significant impact on the reaction process and product purity. Each step of the reaction needs to be carefully regulated to obtain 2-chloro-N - [4 - (1-cyanocyclopentyl) phenyl] -3 -pyridineformamide in high yield and purity.
What are the physical properties of 2-chloro-N- [4- (1-cyanocyclopentyl) phenyl] -3-Pyridinecarboxamide?
2-Chloro-N- [4- (1-cyanocyclopentyl) phenyl] -3-pyridineformamide, the physical properties of this substance are related to many aspects.
Its appearance is often in a specific form, mostly in the form of a solid, but the specific color state may vary depending on the preparation method and purity. Or white to off-white powder with fine texture and uniform appearance.
As for the melting point, it is one of its important physical properties. The value of the melting point is about a specific temperature range, and this value is quite critical in the identification and purification of this compound. By accurately measuring the melting point, the purity of the compound can be clarified. If the melting point is consistent with the theoretical value and the melting range is very narrow, it indicates that the purity of the compound is quite high; conversely, if the melting range is wide, it implies that it may contain impurities.
Furthermore, the solubility cannot be ignored. Among common organic solvents, their solubility varies. Some polar organic solvents, such as ethanol and acetone, may have a certain solubility, which makes them significant in the selection and separation and purification of reaction solvents in organic synthesis. In water, its solubility is relatively low, due to the molecular structure of the compound, the ratio and distribution of polar groups and non-polar groups, resulting in poor hydrophilicity.
density is also a key consideration. Although the exact density value needs to be determined by precise experiments, its density characteristics are also different from those of similar compounds. This physical property plays an important role in the calculation of the relationship between mass and volume of a substance, as well as in the study of the phase behavior of a specific reaction system.
In addition, the stability of this compound varies under different environmental conditions. In a dry environment at room temperature and pressure, its chemical properties are relatively stable and can be stored for a certain period of time without significant chemical changes. However, if exposed to high temperature, high humidity or strong light exposure, or in contact with specific chemical substances, its structure may change, thereby affecting its physical properties and chemical activity.
What is the market outlook for 2-chloro-N- [4- (1-cyanocyclopentyl) phenyl] -3-Pyridinecarboxamide?
Today, there are 2-chloro-N - [4 - (1 - cyanocyclopentyl) phenyl] -3 - Pyridinecarboxamide, which is an organic compound. The market prospect of this compound is quite important.
In the field of Guanfu medicine, this compound may have unique biological activities. Gai has made a name for itself in the treatment of diseases because of its special structure or its combination with specific biological targets. If new anti-cancer drugs are developed, the growth and proliferation process of cancer cells is complicated, and if this compound can precisely act on relevant targets, block the key signaling pathways of cancer cells, or inhibit its growth, it will bring good news to cancer patients. Or in the treatment of neurological diseases, it acts on neurotransmitter receptors or related proteins to regulate nerve signaling and relieve symptoms of neurological disorders such as Alzheimer's disease and Parkinson's disease. Therefore, in the pharmaceutical research and development market, its potential is huge, which is expected to open up new drug research and development directions, attracting many pharmaceutical companies and scientific research institutions to invest resources in in-depth research and development.
Furthermore, in the field of pesticides, it may also have potential. Today's agriculture has an increasing demand for high-efficiency, low-toxicity and environmentally friendly pesticides. If this compound has inhibitory effects on specific physiological processes of pests, such as interfering with the nervous system, respiratory system or growth and development process of pests, it can become an active ingredient of new pesticides. Compared with traditional pesticides, if a good insecticidal effect can be achieved at a lower dose, and the impact on the environment and non-target organisms is small, it will definitely occupy a place in the pesticide market and help the sustainable development of agriculture.
However, its market prospects are not entirely smooth. The process of synthesizing this compound may be challenging. If the synthesis steps are complicated and expensive, it will limit its large-scale production and application. And the development of new drugs requires long clinical trials to ensure their safety and effectiveness, which consumes huge manpower, material resources and time. For pesticides, it is also necessary to pass strict environmental assessment and registration procedures. However, despite the challenges, given the broad demand in the field of medicine and pesticides, with time to overcome the technical difficulties, 2-chloro-N - [4 - (1 - cyanocyclopentyl) phenyl] -3 - Pyridinecarboxamide may be able to shine in the market and bring innovation and development to related industries.