2-chloro-N-[2-(4-chlorophenyl)phenyl]-pyridine-3-carboxamide

This is the naming of an organic compound. According to the naming rules, its chemical structure can be deduced. In "2-chloro-N - [2 - (4 - chlorophenyl) phenyl] -pyridine-3 - carboxamide", the "2-chloro" epipyridine ring has chlorine atom substitution at the 2nd position; "pyridine-3 - carboxamide" indicates that the parent nucleus of the compound is pyridine-3 - formamide; "N - [2 - (4 - chlorophenyl) phenyl]" means that the nitrogen atom is connected to a 2- (4 - chlorophenyl) phenyl group.
When drawing its structure, draw the pyridine ring first, with a formamide group at the 3rd position and a chlorine atom at the 2nd position. The substituent on the nitrogen atom is first drawn with a phenyl group, which is connected to another phenyl group at the 2nd position. This phenyl group has a chlorine atom at the 4th position. In this way, the chemical structure of "2 - chloro - N - [2 - (4 - chlorophenyl) phenyl] - pyridine - 3 - carboxamide" can be obtained.

2 - chloro - N - [2 - (4 - chlorophenyl) phenyl] - pyridine - 3 - carboxamide, this is the name of an organic compound. It has important uses in today's medicine, chemical industry and other fields.
In the field of medicine, such compounds are often used as active ingredients to lay the foundation for the development of new drugs. Because of its unique chemical structure, it may act precisely on specific biological targets in the human body, and interact with specific receptors and enzymes to regulate human physiological processes and achieve the effect of treating diseases. Or it can inhibit the proliferation of cancer cells and show its presence in the field of cancer treatment; or it can regulate the function of the nervous system and be used for the prevention and treatment of neurological diseases.
In the chemical industry, this compound may be used as an intermediate to participate in the synthesis of complex organic compounds. With its structural properties, it is converted into materials with special properties through a series of chemical reactions. It can be used to make high-performance plastics and coatings, endowing products with better stability, corrosion resistance and other characteristics, and improving product quality and application range.
In addition, in terms of scientific research and exploration, this compound is also an important research object. Scientists deepen their understanding of the basic principles of organic chemistry by studying its physical and chemical properties and reaction mechanisms, promote the innovation and development of organic synthesis methodologies, and provide ideas and methods for the creation of more new compounds.
Overall, 2 - chloro - N - [2 - (4 - chlorophenyl) phenyl] - pyridine - 3 - carboxamide plays a key role in the development of modern science and technology, and has broad application prospects and research value in the fields of medicine, chemical industry and scientific research.

2-Chloro-N - [2- (4-chlorophenyl) phenyl] -pyridine-3-formamide, this is an organic compound. Its physical properties are crucial for its application in many fields.
First, the appearance of this compound is often white to quasi-white crystalline powder, fine and uniform, and the appearance is quite textured. Such appearance characteristics are quite helpful in identifying and preliminarily judging its purity.
Besides the melting point, after careful determination, its melting point is roughly in a specific temperature range. The melting point is an important physical constant of the substance, by which the purity of the compound can be determined. If the purity is high, the melting point is sensitive and in line with the theoretical value; if it contains impurities, the melting point will shift and the melting range will become wider.
Its solubility is also worthy of attention. In organic solvents, such as common ethanol and dichloromethane, it exhibits a certain solubility. In ethanol, moderate heating and stirring can better dissolve to form a clear solution. In water, its solubility is poor and only slightly soluble. This difference in solubility has a profound impact on its application in different systems. In organic synthesis reactions, suitable solvents can be selected according to their solubility to promote the smooth progress of the reaction.
In addition, the density of the compound is relatively stable, and under certain conditions, its density value is specific. The property of density is very important when it comes to the quantitative access of substances and the study of mixing systems, and can provide key parameters for precise experimental operations.
In summary, the physical properties of 2-chloro-N- [2- (4-chlorophenyl) phenyl] -pyridine-3-formamide, such as appearance, melting point, solubility and density, have their own characteristics and are related to each other, laying the foundation for their application in chemical and pharmaceutical fields.

The synthesis of 2-chloro-N - [2 - (4-chlorophenyl) phenyl] -pyridine-3-formamide is a key research point in the field of organic synthesis. In the past, many talents have dedicated themselves to exploring efficient methods to form this compound.
One method is to use pyridine-3-formic acid as the starting material. Shilling pyridine-3-formic acid is co-heated with thionyl chloride, and the carboxyl group in pyridine-3-formic acid can be converted into an acyl chloride to obtain pyridine-3-formyl chloride. In this step, attention should be paid to the control of the reaction temperature. If the temperature is too high, side reactions will occur, and if it is too low, the reaction will be delayed. After that, 2 - (4 - chlorophenyl) aniline is slowly added. In the presence of appropriate bases, such as triethylamine, nucleophilic substitution reactions can occur between the two. The action of the base is to neutralize the hydrogen chloride generated by the reaction, which prompts the reaction to proceed forward, and the final product is 2 - chloro - N - [2 - (4 - chlorophenyl) phenyl] -pyridine - 3 - formamide.
Another method is to use 2 - chloropyridine - 3 - formic acid as the starting material. First, it is made into an active ester, which can be reacted with p-nitrophenol to obtain 2-chloropyridine-3-p-nitrophenyl formate. The activity of this active ester is quite high, and when it meets 2- (4-chlorophenyl) aniline, under mild conditions, the aminolysis reaction can occur smoothly to form the target product. The advantage of this approach is that the reaction conditions are relatively mild and there are few side reactions, so it is difficult to obtain or store the starting material 2-chloropyridine-3-formic acid.
Furthermore, there are methods based on the coupling reaction catalyzed by palladium. The Buchwald-Hartwig coupling reaction of halogenated pyridine derivatives and halogenated benzene derivatives occurs in the presence of palladium catalysts, such as tetra (triphenylphosphine) palladium, and ligands. This reaction requires fine regulation of the type and dosage of the reaction solvent and base, so that the two can be effectively coupled. After subsequent amidation, 2-chloro-N - [2 - (4-chlorophenyl) phenyl] -pyridine-3-formamide can be obtained. This method can construct complex aryl-aryl bonds, but palladium catalysts are expensive and hinder large-scale synthesis.

2-Chloro-N - [2 - (4-chlorophenyl) phenyl] -pyridine-3-formamide, this is an organic compound. When it comes to the potential safety risks of this substance, I should state in detail.
The first word about its toxicity. If this compound is ingested, inhaled or absorbed through the skin, it may be harmful to the human body. It may cause specific toxic effects in animal experiments, such as affecting the function of organs, damaging important organs such as the liver and kidneys, resulting in abnormal function. It may also affect the nervous system, causing behavioral changes, neurological disorders and other conditions.
Furthermore, the risk of explosion is discussed. Although it is not a typical flammable and explosive substance, under certain conditions, in case of hot topic, open flame or strong oxidant, there may be a risk of combustion or even explosion. Due to the structural characteristics of organic compounds, under external stimulation, chemical bonds or violent changes can cause dangerous reactions.
Repeat its environmental risk. If it flows into the environment, it may be difficult to degrade rapidly due to its chemical stability. Or accumulate in soil and water, endangering the ecosystem. It may be toxic to aquatic organisms, affecting their survival and reproduction, and destroying the balance of aquatic ecology.
When handling this compound, strict safety procedures must be followed. Experimenters need to wear protective clothing, protective gloves and goggles, and work in a well-ventilated manner to prevent inhalation or contact. When storing, it should be placed in a cool, dry and ventilated place, away from fire, heat sources and oxidants. In this way, potential safety risks can be minimized and personal and environmental safety can be ensured.