2 Chloro 6 Aminopyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-6-aminopyridine

    Specifications

    HS Code

    685417

    Chemical Formula C5H5ClN2
    Molecular Weight 128.56 g/mol
    Appearance Solid
    Color Typically white to off - white
    Odor May have a characteristic amine - like odor
    Melting Point 105 - 107 °C
    Boiling Point 264 - 266 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, dichloromethane
    Pka ~3.7 (approximate value for the pyridinium ion formation)

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    General Information
    Where to Buy 2-Chloro-6-aminopyridine in China?
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    Frequently Asked Questions

    As a leading 2-Chloro-6-aminopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Chloro-6-aminopyridine?
    2-Chloro-6-aminopyridine is one of the organic compounds with a wide range of uses and important applications in many fields.
    First, in the field of medicinal chemistry, this compound is often a key intermediate. In terms of the synthesis of specific drugs, its structural properties allow chemists to chemically modify it to construct molecular structures with specific biological activities. For example, when developing drugs targeting specific disease targets, 2-chloro-6-aminopyridine can be used as a starting material. After multi-step reactions, it can be connected to other functional groups or structural fragments to create drug molecules that can precisely act on disease-related proteins or receptors, providing an important material basis for pharmaceutical research and development.
    Second, in the field of pesticide chemistry, 2-chloro-6-aminopyridine also has significant functions. Due to its chemical properties, it can be used to synthesize new pesticides. Such pesticides may have high-efficiency insecticidal and bactericidal properties, and have relatively little impact on the environment. Taking the synthesis of new insecticides as an example, its unique structure helps to interact with specific biomolecules in insects, interfering with the normal physiological activities of insects, achieving the purpose of efficient insecticidal, and assisting in the prevention and control of pests and diseases in agricultural production.
    Third, in the field of materials science, 2-chloro-6-aminopyridine can participate in the preparation of functional materials. By reacting with other compounds, materials with special electrical, optical or mechanical properties can be formed. For example, when synthesizing some optoelectronic materials, as a structural unit, it can regulate the electronic transport properties or luminescence properties of the materials, and is expected to be applied to the manufacture of optoelectronic devices such as organic Light Emitting Diodes (OLEDs), promoting the development of materials science.
    In summary, 2-chloro-6-aminopyridine plays a key role in the fields of medicine, pesticides and materials science due to its unique chemical structure and properties, providing an indispensable material support for technological innovation and development in various fields.
    What are the physical properties of 2-Chloro-6-aminopyridine?
    2-Chloro-6-aminopyridine is one of the organic compounds. It has specific physical properties and is worth exploring.
    First of all, under room temperature, 2-chloro-6-aminopyridine is mostly white to light yellow crystalline powder, with fine texture. This form is easy to store and use, and provides convenience in many chemical operations.
    times and melting point, about 134-138 ℃. Melting point is an important physical property of a substance. In this temperature range, 2-chloro-6-aminopyridine gradually melts from a solid state to a liquid state. This transition has a profound impact on its application under different temperature conditions. For example, in some chemical reactions that require precise temperature control, the exact value of the melting point is related to the reaction process and product purity.
    Furthermore, when it comes to solubility, it is slightly soluble in water, but it exhibits better solubility in organic solvents such as methanol, ethanol, and dichloromethane. This solubility characteristic allows chemists to choose suitable solvents according to their characteristics when designing reaction systems or separating and purifying products, thereby optimizing the experimental process and improving the reaction efficiency.
    As for the boiling point, although the exact data varies depending on the measurement conditions, it is roughly in a specific temperature range. The boiling point is also a key indicator for measuring the physical properties of a substance. It is related to the temperature point at which a substance is converted from a liquid state to a gas state during the heating process. It plays an important role in indicating its behavior in separation operations such as distillation and high temperature reaction environments.
    The physical properties of 2-chloro-6-aminopyridine are of great significance in many fields such as organic synthesis and drug development, providing a basic basis for chemists to use this compound to carry out various research and production practices.
    2-Chloro-6-aminopyridine chemical synthesis methods
    The chemical synthesis of 2-chloro-6-aminopyridine has many different paths. The common one is to use pyridine as the starting material. After the pyridine is modified with appropriate protective groups, under specific reaction conditions, the chlorine atom is introduced at the second position. This can be achieved by halogenation reaction, such as under the action of suitable halogenating reagents and catalysts, the chlorine atom is precisely replaced at the target position. Then, the amino group is introduced into the sixth position. It can be achieved by first introducing a suitable functional group at the sixth position, which is converted into an amino group by subsequent reactions, such as by the reduction of nitro groups.
    Second, other nitrogen-containing heterocyclic compounds can also be used as starting materials. To modify its structure, chlorine atoms and amino groups are gradually introduced. For example, a compound with a pyridine-like skeleton is first constructed, and chlorine atoms and amino groups are introduced into the corresponding positions in sequence through a series of substitution, addition and other reactions. During the reaction process, attention should be paid to the precise control of reaction conditions, such as temperature, pH, reaction time, etc., which all have a great impact on the selectivity and yield of the reaction. Different reaction paths have their own advantages and disadvantages. In actual operation, it is necessary to comprehensively weigh many factors such as the availability of raw materials, the ease of control of reaction conditions, and cost-effectiveness to choose the most suitable synthetic route.
    2-Chloro-6-aminopyridine to pay attention to when storing and transporting
    2-Chloro-6-aminopyridine is also an organic compound. During storage and transportation, many matters must be paid attention to.
    First words storage. This compound should be stored in a cool, dry and well-ventilated place. Cover because of its nature or affected by temperature and humidity, high temperature and humid place, easy to cause its deterioration. Therefore, it is crucial to choose a suitable storage environment. Keep the storage place away from fire and heat sources. Because the compound may be flammable, it may be dangerous to encounter open flames and hot topics. And it should be stored separately from oxidizing agents, acids, alkalis, etc., to prevent chemical reactions caused by interaction, resulting in changes in material properties, and even dangerous accidents.
    Second on transportation. During transportation, the packaging must be tight to prevent leakage. Transportation vehicles should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. During driving, avoid exposure to the sun, rain, and high temperature. Drivers and escorts should also be familiar with the nature of the chemical and emergency treatment methods. Check the condition of the goods regularly during the journey. If there is any abnormality, dispose of it immediately. During loading and unloading, the operation should be light and light to prevent damage to the packaging and containers, so as to avoid the leakage of the substance and cause harm to the environment and people.
    In short, the storage and transportation of 2-chloro-6-aminopyridine should be treated with caution and strictly abide by relevant procedures to ensure safety.
    What is the market price of 2-Chloro-6-aminopyridine?
    2-Chloro-6-aminopyridine is also a chemical substance. Its market price often changes over time and varies for many reasons.
    Looking at the market conditions of the past, the price of this substance is determined by the abundance of raw materials, the difficulty of preparation, and the amount of need. If the raw materials are abundant, the preparation method is simple, and there are few people who ask for it, the price may become cheaper. On the contrary, if the raw materials are scarce, difficult to make, and there are many users, the price will be high.
    Taste the past, when the production of raw materials suffered a disaster, resulting in a lack of supply, the price of 2-chloro-6-aminopyridine rose rapidly like a roc. Various industrial enterprises compete to buy, in order to meet the needs of production, so the market is very tight for this product, and the price is high and difficult to climb.
    If the preparation technology is innovative, saving time and effort, and the cost is greatly reduced, the price may also fall. In addition, there are competing products on the market, in order to compete for market profits, the price may also be reduced to invite buyers.
    However, if you want to know the current market price of 2-chloro-6-aminopyridine, you can get the real-time price when you consult the commercial stores of chemical raw materials, or visit the platform of the city, so as not to be mistaken by outdated prices. And the chemical industry is changing, so you must always pay attention to it to understand the trend of its price and make a proper policy.