2 Chloro 6 7 Dihydro 5h Pyrrolo 3 4 B Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine

    Specifications

    HS Code

    316544

    Chemical Formula C7H7ClN2
    Molecular Weight 154.597 g/mol
    Appearance Solid (predicted)
    Boiling Point 300.7±37.0 °C at 760 mmHg (predicted)
    Melting Point 124 - 126 °C
    Density 1.342±0.06 g/cm3 at 20 °C (predicted)
    Flash Point 135.6±26.5 °C (predicted)
    Logp 1.59 (predicted)
    Pka 3.98±0.20 (predicted)
    Solubility Soluble in organic solvents like dichloromethane

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    General Information
    Where to Buy 2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine in China?
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    Frequently Asked Questions

    As a leading 2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-Chloro-6, 7-dihydro-5H-pyrrolo [3,4-b] pyridine
    2-Chloro-6,7-dihydro-5H-pyrrolido [3,4-b] pyridine is an organic compound with unique physical properties. It is mostly in a solid state at room temperature, but it also varies according to its purity and crystal form.
    Looking at its melting point, relevant research data show that due to the interaction and arrangement of atoms in the molecular structure, the melting point is in a specific range, and the specific value fluctuates due to experimental conditions and sample purity. Its solubility in organic solvents is quite considerable. Organic solvents such as chloroform, dichloromethane, N, N-dimethylformamide, etc. have good solubility to it. This is because the compound molecule and the organic solvent molecule can form interactions such as van der Waals force, hydrogen bond, etc., so that it can be uniformly dispersed in the solvent.
    As for its boiling point, it is affected by the intermolecular forces, such as hydrogen bonds, dipole-dipole interactions, etc. It needs to reach a certain temperature to overcome these forces before it can be converted from liquid to gaseous state.
    When it comes to density, it is similar to many organic compounds, slightly greater than the density of water. In the field of chemical engineering and chemical research, this property is of great significance for operations such as separation and purification of substances.
    Its appearance, when pure, is often white to light yellow solid powder. However, due to the influence of impurity mixing or storage conditions during the synthesis process, the appearance may change. The physical properties of this compound lay a solid foundation for its application in organic synthesis, medicinal chemistry and other fields. In organic synthesis, the appropriate reaction solvent and reaction temperature can be selected according to its solubility, melting point and other properties to improve the reaction efficiency and product purity. In the field of medicinal chemistry, these properties are closely related to the pharmacokinetic properties of drug absorption, distribution, metabolism, etc., and are crucial for the development of high-efficiency and low-toxicity drugs.
    What are the chemical synthesis methods of 2-Chloro-6, 7-dihydro-5H-pyrrolo [3,4-b] pyridine
    The chemical synthesis method of 2-chloro-6,7-dihydro-5H-pyrrolido [3,4-b] pyridine covers a variety of pathways. One method can also be started by a suitable pyridine derivative. First take the pyridine parent body, under specific conditions, make it meet the chlorine-containing reagent, and the chlorine atom can be introduced into a specific position to form a chloropyridine-containing intermediate. This chlorine-containing intermediate, after ingenious cyclization reaction, goes through several steps, such as in a suitable solvent, promoted by a specific catalyst, so that the chemical bonds in the molecule are rearranged and closed, and then gradually form the basic structure of pyrrolido [3,4-b] pyridine. < Br >
    There are other methods, or start with pyrrole compounds with active double bonds. The pyrrole compound is reacted with a suitable electrophilic reagent, and part of the structure of pyridine is first introduced into the pyrrole system through electrophilic addition and other reactions. Subsequently, the obtained product is subjected to a chlorination step, and the reaction conditions, such as temperature and ratio of reactants, are precisely regulated, so that the chlorine atom is exactly replaced at the target position, thereby obtaining 2-chloro-6,7-dihydro-5H-pyrrolido [3,4-b] pyridine.
    Furthermore, a multi-step tandem reaction strategy can also be used. A series of successive reaction steps are carefully designed to complete the transformation and construction of different functional groups in the same reaction system. The prototype of pyrrolidine is formed first, and then the 2-chlorine substitution is precisely realized through selective chlorination. This process requires strict control of the reaction conditions of each step in order to obtain a pure target product. All methods have their own advantages and disadvantages, and the actual choice needs to be made carefully according to the experimental conditions, the availability of raw materials and the purity requirements of the target product.
    2-Chloro-6,7-dihydro-5H-pyrrolo [3,4-b] pyridine is used in which areas
    2-Chloro-6,7-dihydro-5H-pyrrolido [3,4-b] pyridine is useful in many fields.
    In the field of medicine, this compound has attracted much attention. Due to its unique chemical structure, it can be used as a potential drug intermediate. Chemists can modify and modify its structure to develop new drugs with specific biological activities. For example, derivatives based on this can be designed and synthesized for specific disease-related biological targets, or it may be a good drug for the treatment of difficult diseases such as cancer and neurological diseases. The occurrence and development of causative diseases are closely related to the functional abnormalities of specific biomolecules, and this compound can be rationally designed to precisely regulate the activities of these biomolecules for the purpose of treating diseases.
    In the field of organic synthesis chemistry, 2-chloro-6,7-dihydro-5H-pyrrolido [3,4-b] pyridine is also an important building block. Organic synthesis aims to build complex and functional organic molecules. The special structure of this compound can participate in a variety of organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc. Chemists can use these reactions to connect them with other organic fragments to build more complex and diverse organic compounds, enrich the "toolbox" of organic synthesis, and provide powerful means for the synthesis of new functional materials and total synthesis of natural products.
    In the field of materials science, it has also emerged. With the development of science and technology, the demand for new functional materials is increasing. Materials synthesized based on this compound may have unique electrical, optical or mechanical properties. For example, with specific design, materials with good photoelectric conversion properties can be prepared for use in solar cells to improve energy conversion efficiency; or materials with special fluorescence properties can be prepared for use in biological imaging, fluorescence sensors, etc., opening up new paths for the development of materials science.
    What is the market outlook for 2-Chloro-6,7-dihydro-5H-pyrrolo [3,4-b] pyridine
    2-Chloro-6,7-dihydro-5H-pyrrolido [3,4-b] pyridine, which has considerable market prospects today.
    From the perspective of various fields of chemical industry, it is an important organic synthesis intermediate. Taking pharmaceutical chemistry as an example, the development of many innovative drugs depends on it as a starting material. The current trend of pharmaceutical research and development has led to an increasing demand for new high-efficiency and low-toxicity drugs. The unique structure of this compound gives it significant advantages in building complex drug molecular frameworks, and can provide researchers with a variety of synthesis strategies. Therefore, the market for drug synthesis is on the rise.
    In the field of materials science, with the rise of new functional materials, 2-chloro-6,7-dihydro-5H-pyrrolido [3,4-b] pyridine has also emerged. Due to the special electronic properties endowed by its structure, it can be applied to the preparation of organic optoelectronic materials. With the development of electronic products towards thinness and efficiency, the market demand for organic optoelectronic materials has surged. As a potential key raw material, the market prospect of this compound is also bright.
    Furthermore, with the deepening of scientific research, the research on its derivatization reaction continues to expand. More novel derivatives have been created to further enrich their application fields. Coupled with the continuous development of the global chemical industry, the continuous optimization of raw material supply and synthesis technology, there may be room for cost reduction, which is more conducive to its promotion and application in the market. In summary, 2-chloro-6,7-dihydro-5H-pyrrole [3,4-b] pyridine has unlimited business opportunities in the future market and is expected to shine in many fields.
    What are the manufacturers of 2-Chloro-6,7-dihydro-5H-pyrrolo [3,4-b] pyridine
    2-Chloro-6,7-dihydro-5H-pyrrolido [3,4-b] pyridine is an important organic compound with key applications in many fields such as medicinal chemistry and materials science. As for its manufacturers, there are many in the world, and I will come to you one or two.
    First of all, abroad, BASF in Germany has a long-standing reputation. Its chemical production process is exquisite, and it has a lot of experience in the production of organic compounds, or is involved in the production of this compound. Dow Chemical Company in the United States is also a leader in the industry, with excellent R & D and capacity, and may also be one of its manufacturers.
    Looking at China, many chemical companies are also involved in the production of this compound. For example, a large chemical enterprise in Jiangsu, with organic synthetic products as its core business, may have the ability to produce 2-chloro-6,7-dihydro-5H-pyrrolido [3,4-b] pyridine by virtue of advanced technology and equipment. There are also chemical manufacturers in Shandong, focusing on the manufacture of fine chemicals, which may be involved in the production of this compound.
    However, there are many variables in chemical production, and the production status of each manufacturer may change with market demand and technological innovation. To know the exact manufacturer, you need to consult the chemical product directory, industry reports, or consult professionals in the chemical field to obtain accurate information.