2-Chloro-5-pyridinecarbaldehyde

2-Chloro-5-pyridyl formaldehyde is a kind of organic compound. Its properties are similar to white to light yellow crystalline powder, which is quite stable at room temperature and pressure.
In terms of physical properties, its melting point is between 71-75 ° C, which makes it undergo phase transition in a specific temperature range. It is slightly soluble in water, but easily soluble in organic solvents such as ethanol, ether, and dichloromethane. This difference in solubility is due to the combined action of the polar and non-polar parts of its molecular structure.
In terms of chemical properties, its aldehyde groups are quite active. The aldehyde group can participate in many chemical reactions, such as oxidation reactions. Under the action of suitable oxidants, the aldehyde group can be oxidized to a carboxyl group to form 2-chloro-5-pyridinecarboxylic acid. Another example is reduction reactions. With the help of suitable reducing agents, the aldehyde group can be reduced to an alcohol hydroxyl group to obtain 2-chloro-5- (hydroxymethyl) pyridine.
At the same time, the chlorine atom in this compound also has certain reactivity. In nucleophilic substitution reactions, chlorine atoms can be replaced by nucleophiles such as hydroxyl groups and amino groups. For example, under basic conditions, chlorine atoms may be replaced by hydroxyl groups to generate 2-hydroxy-5-pyridinal formaldehyde. Due to its special chemical properties, 2-chloro-5-pyridyl formaldehyde is widely used in the field of organic synthesis and is often used as a key intermediate in the preparation of a variety of drugs, pesticides and other fine chemicals.

2-Chloro-5-pyridyl formaldehyde is an important chemical raw material in organic synthesis. It has a wide range of uses and has significant applications in many fields such as medicine, pesticides, and material science.
In the field of medicine, it is often the key intermediate for the synthesis of drugs. For many bioactive compounds, this is often used as the starting material in the synthesis path, and through a series of chemical reactions, the molecular structure with specific pharmacological activities is constructed. For example, for some therapeutic drugs for specific diseases, 2-chloro-5-pyridyl formaldehyde plays an indispensable role in the initial step of its synthesis to introduce key functional groups and then shape the overall structure of drug molecules. < Br >
In the field of pesticides, this compound can be used to prepare high-efficiency, low-toxicity and environmentally friendly pesticides. By chemical modification and derivatization, pesticide varieties with high selectivity and significant killing effect on pests can be created. Due to its unique structure, it can interact with specific targets in pests, interfere with the normal physiological metabolism of pests, and achieve the purpose of pest control.
In the field of materials science, 2-chloro-5-pyridine formaldehyde also has outstanding performance. It can be used to synthesize organic materials with special optical, electrical or mechanical properties. For example, in the synthesis of organic optoelectronic materials, its participation in the reaction can endow the material with specific electron transport properties or luminescence properties, laying the foundation for the preparation of high-performance organic Light Emitting Diodes, solar cells and other optoelectronic devices.
In summary, 2-chloro-5-pyridyl formaldehyde has shown important application value in many fields due to its unique chemical structure, promoting the development and progress of related industries.

The method of synthesizing 2-chloro-5-pyridine formaldehyde often follows several paths. First, it can be started from a pyridine derivative. First, a suitable pyridine compound is taken, and under specific conditions, the chlorine atom is introduced into the second position of the pyridine ring. This chlorination reaction requires careful selection of reagents and reaction environments. If pyridine is used as a substrate, it can be co-reacted with a chlorine-containing reagent in the presence of a catalyst by heating to promote the selective occupation of the chlorine atom in the second position. Thereafter, the aldehyde group is introduced into the fifth position. The formyl group can be successfully connected to the fifth position by a suitable formylating reagent, such as in a mild alkaline environment, to obtain 2-chloro-5-pyridine formaldehyde.
Second, other raw materials containing pyridine structures can also be used. For example, some pyridine analogs with substituents that can be converted into chlorine atoms and aldehyde groups. First, one of the substituents is converted into chlorine through a specific reaction, and then the other substituent is modified into an aldehyde group through a subsequent reaction. In this process, precise control of the reaction conditions is crucial. Temperature, reaction time, and the nature of the solvent used will all have a significant impact on the reaction process and product yield. And each step of the reaction needs to be reasonably connected to ensure the efficiency and feasibility of the entire synthesis route. These methods are common strategies for synthesizing 2-chloro-5-pyridine formaldehyde.

2-Chloro-5-pyridyl formaldehyde is an organic compound. During storage and transportation, the following numbers must be paid attention to:
One is stability considerations. This compound should be stored in a cool, dry and well-ventilated place, away from fires and heat sources. Because it is heated or exposed to open flames, it may burn, and it is easy to decompose when heated, resulting in harmful gases. Therefore, maintaining a suitable temperature and humidity is crucial to ensure its chemical stability.
The second is about packaging. Appropriate packaging materials should be used, and the packaging should be tight and sealed. It is usually better to hold it in glass bottles or metal drums, and avoid using materials that are prone to react with the compound. This can prevent its leakage, and also avoid deterioration in contact with air, moisture, etc.
The third is to avoid contact with contraindications. 2-Chloro-5-pyridyl formaldehyde should not be mixed or mixed with strong oxidants, strong bases and other substances. Because of its encounter with strong oxidants, it may cause a violent oxidation reaction; contact with strong bases may cause chemical reactions, which in turn affect its quality and even generate dangerous products.
Fourth, in terms of transportation. The transportation process must be careful to prevent collision and friction. Vehicles should have good shock absorption facilities to prevent packaging damage. And transportation personnel need to be professionally trained and familiar with the properties of the compound and emergency treatment methods.
The last is the storage mark. The storage place should have a clear warning mark indicating its danger, such as "flammable" and "harmful", so that personnel can identify it, and at the same time be equipped with corresponding fire protection and emergency equipment to deal with emergencies.
Adhering to the above precautions, we must ensure the safety of 2-chloro-5-pyridine formaldehyde during storage and transportation, avoid accidents, and protect the safety of personnel and the environment.

What you are asking about is the market price range of 2-chloro-5-pyridine formaldehyde. However, the price of this compound often varies due to various factors, and it is difficult to determine a certain number.
Its price is related to the cost of raw materials. The production of raw materials, market supply and demand all affect their price. If raw materials are scarce or demand increases sharply, resulting in high prices, the production cost of 2-chloro-5-pyridine formaldehyde will rise, and its market price will also rise.
Furthermore, the complexity of the production process also has an impact. If the process is complex, high-end equipment, special reagents, or multiple processes are required, energy consumption and labor costs will increase, and the product price will increase.
The relationship between supply and demand in the market is also key. If the market demand for this compound is strong, but the supply is limited, the price will rise; conversely, if the supply is abundant and the demand is weak, the price may drop.
In addition, the sales regions and channels are different, and the prices are also different. In developed regions, due to factors such as transportation and storage costs, the price may be higher than in other regions. And through different channels such as direct sales and agents, the price will also be different.
In summary, the market price range of 2-chloro-5-pyridyl formaldehyde is difficult to determine precisely, ranging from a few yuan per gram to tens of yuan per gram or even higher, depending on the actual raw materials, process, supply and demand, and sales conditions.