2 Chloro 5 Iodo 3 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-chloro-5-iodo-3-(trifluoromethyl)pyridine

    Specifications

    HS Code

    581881

    Chemical Formula C6H2ClF3IN
    Molecular Weight 319.44

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    General Information
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    Frequently Asked Questions

    As a leading 2-chloro-5-iodo-3-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-chloro-5-iodo-3- (trifluoromethyl) pyridine
    2-Chloro-5-iodine-3- (trifluoromethyl) pyridine is one of the organic compounds. Its physical properties are of great value for investigation.
    Looking at its morphology, under room temperature and pressure, it is mostly colorless to light yellow liquid. This state makes it more fluent in many reaction systems. It can participate in the reaction smoothly. Because of its good fluidity, it is more fully in contact with other reactants, which is conducive to the progress of the reaction.
    When it comes to odor, it often has a special pungent odor, which may be caused by the presence of chlorine, iodine and trifluoromethyl in the molecular structure. The presence of this odor, although it may bring some inconvenience to its application, is also an important characteristic for identifying the substance.
    As for the boiling point, it is about a certain temperature range, which is of great significance when separating and purifying the compound. By means of distillation and other means, according to the difference in boiling points, the substance can be accurately obtained from the mixture to ensure its purity.
    Melting point is also a key physical property. This value is related to the transition temperature between the solid and liquid states of the compound, and provides an important reference for the setting of its storage and transportation conditions. The density of
    has a specific value. This parameter affects the distribution of the substance in different media. In liquid-liquid extraction and other operations, it provides important clues for the design of separation schemes.
    In terms of solubility, it has good solubility in common organic solvents such as dichloromethane and chloroform, but relatively low solubility in water. This characteristic determines the selection range of organic solvents during synthesis and subsequent treatment, and also facilitates the separation and purification of the reaction products.
    In summary, the physical properties of 2-chloro-5-iodine-3- (trifluoromethyl) pyridine play an indispensable role in its synthesis, application and treatment. In-depth understanding of these properties can better control the compound in various chemical processes.
    What are the synthesis methods of 2-chloro-5-iodo-3- (trifluoromethyl) pyridine
    There are several common methods for synthesizing 2-chloro-5-iodine-3- (trifluoromethyl) pyridine.
    First, the compound containing the pyridine structure is used as the starting material, and chlorine and iodine atoms are introduced by halogenation reaction. First, the pyridine is modified by specific groups to make the reaction check point tend to the target position. In a suitable solvent, under the action of a catalyst, chlorination is carried out with chlorine-containing reagents, such as thionyl chloride, etc., and chlorine atoms can be introduced at specific positions in the pyridine ring. Subsequently, a suitable iodizing reagent, such as iodine, is selected with an appropriate oxidizing reagent, and the reaction is carried out under suitable conditions to introduce the iodine atom into the target check point, while ensuring that the trifluoromethyl group is not affected. This process requires precise control of the reaction conditions, such as temperature, reaction time and reagent dosage, in order to improve the yield and purity of the target product.
    Second, the strategy of gradually constructing pyridine rings is adopted. First, the intermediate containing part of the target substituent is synthesized, and then the pyridine ring is constructed by cyclization reaction. For example, starting with an organic compound containing trifluoromethyl groups, a chain or cyclic intermediate with suitable substituents is formed through a series of reactions. Subsequently, the pyridine ring is formed by cyclization reaction, and chlorine and iodine atoms are introduced through halogenation during or after cyclization. This method requires fine regulation of the reaction steps and the reactivity of the intermediate to achieve the desired synthetic effect.
    Third, the coupling reaction catalyzed by transition metals. The coupling reaction is carried out with a pyridine derivative containing chlorine or iodine as a substrate and a reagent containing trifluoromethyl groups under the action of a transition metal catalyst such as a palladium catalyst. By selecting appropriate ligands and reaction conditions to promote the formation of carbon-carbon bonds or carbon-halogen bonds, trifluoromethyl is introduced into the pyridine ring and the substitution of chlorine and iodine atoms at the target position is achieved. This method requires high activity and selectivity of catalysts, and the reaction system needs to be optimized to improve the reaction efficiency.
    What is the main use of 2-chloro-5-iodo-3- (trifluoromethyl) pyridine?
    2-Chloro-5-iodine-3- (trifluoromethyl) pyridine, this is an organic compound. It has a wide range of uses in the field of medicine and can be used as a key intermediate to help synthesize many drugs with specific biological activities. The structure of the Gainpyridine ring and the properties of atoms containing fluorine, chlorine, and iodine endow the compound with unique physical and chemical properties and biological activities. It can act on specific biological targets, or have antibacterial, anti-inflammatory, and anti-tumor effects.
    It is also indispensable in the field of pesticides. It can be used as an important raw material for the synthesis of new pesticides. With its special structure, it can exhibit good insecticidal, bactericidal or herbicidal activities. Due to the presence of fluorine atoms, it can enhance the lipid solubility and stability of compounds, improve their retention and biological activity in the environment, and effectively control crop diseases and pests, and ensure crop growth.
    In terms of materials science, it can participate in the synthesis of functional materials. Such as pyridine-containing structural polymers or organometallic complexes, it can be applied to optical materials, electronic materials and other fields. Pyridine rings can coordinate with metal ions to form complexes with special photoelectric properties, which can be used to prepare Light Emitting Diodes, sensors and other devices, providing new avenues and possibilities for the development of materials science. Overall, 2-chloro-5-iodine-3- (trifluoromethyl) pyridine has important application value in many fields, promoting technological progress and development in various fields.
    What is the market outlook for 2-chloro-5-iodo-3- (trifluoromethyl) pyridine?
    2-Chloro-5-iodine-3- (trifluoromethyl) pyridine, an organic compound. Looking at the current market prospects, it has a wide range of uses in medicine, pesticides and other fields, and the market potential is considerable.
    In the field of medicine, due to its unique chemical structure, it may act as a key intermediate in the development of new drugs. Today, the global demand for new specific drugs is increasing, and the pharmaceutical industry is developing rapidly, providing broad space for the research and development of drugs containing this compound. For example, the development of some targeted drugs for specific diseases, or the construction of highly active and selective pharmacoactive groups by virtue of their structural characteristics, is expected to give rise to innovative drugs, so the demand for pharmaceutical intermediates may be on the rise in the market.
    In the field of pesticides, the compound may have unique biological activities and can become an important raw material for the creation of new pesticides. Today, green, efficient, and low-toxicity pesticides are the general trend of the industry. Due to its own characteristics, this compound may meet this development demand and be used to develop new pesticides, fungicides, etc. With the advancement of agricultural modernization, the demand for high-quality pesticides continues to rise, and it also has a good opportunity for development in the pesticide intermediates market.
    However, the compound market also has challenges. Its synthesis process may be more complex, involving many reaction steps and special reagents, resulting in high production costs. Cost issues may restrict its large-scale production and marketing activities. And the market competition is fierce, many chemical companies and scientific research institutions or involved in related fields, if they want to seize market share, they need to make great efforts in technological innovation and cost control.
    In summary, although 2-chloro-5-iodine-3 - (trifluoromethyl) pyridine faces challenges such as cost and competition, it has broad application prospects in the fields of medicine and pesticides. If it can break through technical bottlenecks and optimize costs, it will be able to achieve good development in the market.
    What should be paid attention to when storing and transporting 2-chloro-5-iodo-3- (trifluoromethyl) pyridine?
    2-Chloro-5-iodine-3- (trifluoromethyl) pyridine is a chemical substance. During storage and transportation, more attention should be paid.
    The first thing to pay attention to is its chemical properties, which are the basis for storage and transportation. This substance has a halogenated pyridine structure, and the presence of chlorine, iodine and trifluoromethyl makes it unique in nature. Because it contains halogen atoms, it encounters specific reagents or undergoes a substitution reaction; the strong electron absorption of trifluoromethyl affects its chemical activity and stability. Therefore, when storing, it is necessary to choose a dry, cool and well-ventilated place to avoid direct sunlight to prevent reactions caused by light and deterioration.
    and packaging. It is advisable to use tight and corrosion-resistant containers. Although glass containers are transparent and easy to observe, they may encounter strong alkalis and other substances or be corroded, so careful selection is required. Plastic containers are not advisable if they are made of improper materials or interact with the substance. Usually, special chemical reagent bottles lined with anti-corrosion coatings are more suitable. Outside the packaging, their names, characteristics, hazards and other information should be clearly marked for identification and prevention.
    When transporting, follow relevant regulations and standards. Because they may belong to the category of hazardous chemicals, the transportation vehicle must have corresponding qualifications. During transportation, drive steadily and slowly to avoid violent vibrations and collisions, and avoid container damage and material leakage. And the temperature and humidity of the transportation environment also need to be controlled, according to its characteristics, to maintain the appropriate range.
    In addition, staff protection is also key. During storage and transportation operations, staff should be in front of suitable protective equipment, such as protective clothing, gloves, goggles, gas masks, etc., to prevent contact or inhalation of the substance and damage to health.
    In short, when 2-chloro-5-iodine-3 - (trifluoromethyl) pyridine is stored and transported, it is safe to repackage, transport in accordance with regulations, and protect personnel from its characteristics.