2 Chloro 5 Formylpyridine 3 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

2-chloro-5-formylpyridine-3-carbonitrile

    Specifications

    HS Code

    660668

    Name 2-chloro-5-formylpyridine-3-carbonitrile
    Molecular Formula C7H3ClN2O
    Molecular Weight 166.56
    Physical State Solid
    Chemical Class Heterocyclic organic compound
    Reactivity May react with reducing agents, bases, etc. due to aldehyde, cyano and chloro groups

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    General Information
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    Frequently Asked Questions

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    What are the main uses of 2-chloro-5-formylpyridine-3-carbonitrile?
    2-Chloro-5-formylpyridine-3-formonitrile is also an organic compound. Its main use, due to its unique structure, has extraordinary uses in many fields.
    In the field of medicinal chemistry, this compound can be used as a key intermediate. Due to its properties of pyridine ring, chlorine atom, formyl group and formonitrile group, it can be combined with other compounds by chemical synthesis to create new drugs. For example, drugs for specific diseases can be combined with specific biologically active molecules through delicate chemical reactions to form therapeutic drug molecules.
    In the field of materials science, it also has potential uses. Because the functional groups contained in it can participate in the construction reaction of materials. For example, it can be used to react with other monomers or polymers to create new materials with special properties, or optical properties, electrical properties, or even mechanical properties. Materials with unique properties can meet the needs of electronic devices, optical equipment and other fields.
    Furthermore, in the study of organic synthetic chemistry, 2-chloro-5-formylpyridine-3-formonitrile is often an important starting material or reaction reagent. Chemists can use the reactivity of their functional groups to carry out diverse organic reactions, such as nucleophilic substitution reactions, electrophilic substitution reactions, etc., to expand the structural diversity of organic compounds and contribute to the research and development of organic chemistry.
    What are 2-chloro-5-formylpyridine-3-carbonitrile synthesis methods?
    To prepare 2-chloro-5-formylpyridine-3-formonitrile, there are various methods. First, it can be started from a suitable pyridine derivative. First, take the pyridine with a specific substituent, and use an appropriate chlorination reagent, such as a chlorine-containing halogen, under suitable reaction conditions, such as a specific temperature and solvent environment, carry out a chlorination reaction to introduce chlorine atoms into the pyridine ring.
    Then, through a specific formylation step. A suitable formylation reagent can be selected, such as a certain type of formyl-containing compound, in the presence of a specific catalyst, the specific position of the pyridine derivative is formylated to obtain a formyl-containing pyridine intermediate.
    Finally, by introducing a formonitrile group. Using a suitable nitrile reagent, under specific reaction conditions, the formonitrile group is promoted to access the pyridine ring to obtain 2-chloro-5-formylpyridine-3-formonitrile.
    Second, other nitrogen-containing heterocyclic compounds can also be used as starting materials. Chlorine atoms, formyl groups and formonitrile groups are introduced into the pyridine ring through multi-step reaction. This process requires fine control of the reaction conditions of each step, including the proportion of reactants, reaction temperature, reaction time, etc., to ensure that the reaction proceeds in the expected direction, and the final synthesis of the target product 2-chloro-5-formylpyridine-3-formonitrile. After each step of the reaction, it is often necessary to separate and purify to obtain high-purity products.
    What are the physical properties of 2-chloro-5-formylpyridine-3-carbonitrile?
    2-Chloro-5-formylpyridine-3-formonitrile is a kind of organic compound. Looking at its physical properties, first of all, its appearance, under normal conditions, is mostly solid state, color or white to light yellow powder, fine and uniform, the purpose can be regarded as its pure less variegated and foreign matter.
    When it comes to the melting point, the melting point of this compound is quite critical, and it is about a specific temperature range. This temperature range is crucial for the transformation of its physical state and is related to its existence under different conditions. The level of melting point is determined by many factors such as the interaction between atoms in its molecular structure and the strength of chemical bonds. In its molecular structure, the presence of chlorine atoms, formyl groups and formonitrile groups affects the intermolecular forces, which in turn affects the melting point.
    Solubility is also an important physical property. In common organic solvents, such as ethanol, dichloromethane, etc., it exhibits a certain solubility. Ethanol is a polar organic solvent, and 2-chloro-5-formylpyridine-3-formonitrile can form a certain interaction with ethanol molecules because some of the groups in its molecular structure are polar, so it can form a certain interaction with ethanol molecules to dissolve them. In water, because the overall molecular polarity is not enough to form a sufficiently stable interaction with water molecules, the solubility is poor.
    In addition, its density is also a specific value, which reflects its mass per unit volume. Compared with other substances, it can be observed that its physical behavior such as floating or sinking in the mixture. The size of the density is also closely related to the molecular structure, and the type, number and spatial arrangement of atoms all affect it.
    As for the boiling point, although the relevant information may not be detailed, it can be inferred from its structure and similar compounds that under appropriate pressure conditions, when it reaches a certain temperature, it will change from liquid to gaseous. The level of its boiling point is also dominated by intermolecular forces, such as van der Waals forces, hydrogen bonds, etc. Under specific conditions, molecules can overcome such forces and achieve phase transformation.
    What are the chemical properties of 2-chloro-5-formylpyridine-3-carbonitrile?
    2-Chloro-5-formylpyridine-3-formonitrile is an organic compound. Its chemical properties are unique, including chlorine atoms, formyl groups and formonitrile groups, which cause it to exhibit a variety of chemical reactivity.
    Let's talk about the chlorine atom first, which endows the compound with nucleophilic substitution reactivity. Due to its electronegativity, the chlorine atom can be used as a leaving group. Under appropriate conditions, it can be replaced by nucleophilic reagents such as hydroxyl (-OH) and amino (-NH2O), thereby forming new carbon-heteroatom bonds and expanding the structure and function of the compound.
    formyl (-CHO) has significant reactivity. It can participate in oxidation reactions, and under the action of suitable oxidants, it can be converted into carboxyl groups (-COOH), which enhances the acidity of compounds. At the same time, formyl groups are also prone to reduction reactions. Under the action of reducing agents, they can be converted into hydroxymethyl groups (-CH 2O OH), which enriches the functional groups of compounds. In addition, formyl groups can also participate in classic condensation reactions, such as condensation with compounds containing active hydrogen, forming structures such as carbon-carbon double bonds, which greatly enriches the structural types of compounds.
    Fornitrile groups (-CN) are also rich in reactions. It can hydrolyze under acidic or basic conditions to form carboxyl groups or amide groups, realizing the transformation of functional groups and the adjustment of compound properties. Moreover, formonitrile groups can also participate in nucleophilic addition reactions and combine with nucleophiles to derive compounds with different structures.
    2-chloro-5-formylpyridine-3-formonitrile contains functional groups, which have a variety of chemical reactivity and can prepare organic compounds with different structures through different reaction paths, which is of great application value in the field of organic synthesis.
    What 2-chloro-5-formylpyridine-3-carbonitrile need to pay attention to when storing and transporting
    2-Chloro-5-formylpyridine-3-formonitrile is an organic compound. When storing and transporting, the following numbers should be paid attention to:
    First, the storage place must be dry and cool. This compound is afraid of moisture, and moisture can easily lead to adverse reactions such as hydrolysis, resulting in quality damage. A cool place can reduce the risk of decomposition and deterioration due to excessive temperature. As in ancient Tibetan medicine, a dry and cool place should also be selected to prevent its medicinal properties from mutating.
    Second, it should be avoided from being stored and transported with oxidants, reducing agents, acids, bases, etc. This compound has a specific chemical activity. When it encounters the above-mentioned substances, it is easy to cause violent chemical reactions, or cause the risk of combustion and explosion. The ancient people said: "Water and fire are incompatible", and this compound should also be separated from foreign chemicals.
    Third, the packaging must be tight. It is appropriate to use airtight and moisture-proof packaging materials to prevent air and moisture from invading. If the packaging is damaged and the compound is exposed to the outside, not only the quality is not guaranteed, but also substances that are harmful to the human body and the environment may escape.
    Fourth, during transportation, it is very important to prevent shock and collision. Violent vibration or collision may damage the packaging, or cause changes in the internal structure of the compound, causing danger. Just like transporting fragile porcelain, care must be taken.
    Fifth, the place of storage and transportation, the warning label should be clear and prominent. Inform everyone of the danger of this thing, and let the contact person handle it carefully for safety.
    In short, the storage and transportation of 2-chloro-5-formylpyridine-3-formonitrile must be done carefully according to its chemical characteristics to ensure the safety of personnel and the quality of the compound.