2 Chloro 5 Cyano Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-5-Cyano Pyridine

    Specifications

    HS Code

    931981

    Chemical Formula C6H3ClN2
    Molar Mass 138.55 g/mol
    Appearance Solid (usually white to off - white)
    Melting Point 78 - 82 °C
    Solubility In Water Low solubility, slightly polar molecule
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Odor Typically has a faint, characteristic odor
    Stability Stable under normal conditions, but can react with strong acids, bases, and reducing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2-Chloro-5-Cyano Pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-chloro-5-cyanopyridine?
    2-% ammonia-5-aminopyridine, which has a wide range of uses. In the field of medicine, it is a key intermediate in the synthesis of many drugs. Due to the special chemical structure of this compound, it can play a unique role in the construction of complex drug molecular structures, helping to synthesize a variety of drugs with specific pharmacological activities, such as some anti-cancer drugs, anti-infective drugs, etc., providing powerful weapons for human fight against diseases.
    In the field of materials science, 2-ammonia-5-aminopyridine also has important uses. It can participate in the preparation of high-performance polymer materials. By polymerizing with other monomers, it imparts unique properties to the material, such as enhancing the mechanical strength of the material and improving the thermal stability. It is widely used in aerospace, electronic devices and other fields that require strict material properties.
    Furthermore, in the field of organic synthetic chemistry, it is often used as an organic synthesis reagent. With its active amino group, it can participate in many organic reactions, such as nucleophilic substitution reactions, condensation reactions, etc., providing an effective way for the synthesis of organic compounds with diverse structures, helping organic chemists explore new compounds and new reaction paths, and promoting the continuous development of organic chemistry. Overall, 2-ammonia-5-aminopyridine plays an indispensable role in many fields due to its unique chemical properties, which is of great significance to promoting the progress of related industries and disciplines.
    What are the synthesis methods of 2-chloro-5-cyanopyridine?
    There are various methods for the synthesis of 2-% nitrile-5-cyanopyridine, which you describe in detail today.
    First, it can be prepared by cyanidation of pyridine derivatives. Take a suitable pyridine substrate and react with cyanide reagents such as potassium cyanide and sodium cyanide under specific reaction conditions. The reaction temperature, reaction time and proportion of reactants need to be carefully adjusted. For example, in an organic solvent, catalyzed by a transition metal catalyst, cyanide can be selectively introduced into a specific position of the pyridine ring to generate 2-% nitrile-5-cyanopyridine. The key to this method is to choose the appropriate catalyst and reaction conditions to improve the yield and selectivity of the reaction.
    Second, synthesized by the cyanyl substitution reaction of halogenated pyridine. First, the pyridine derivative containing halogen atoms, such as halogenated pyridine, is prepared. After that, it undergoes nucleophilic substitution reaction with cyanide. During the reaction, the polarity of the solvent, the pH of the reaction system and other factors have a great influence on the reaction process and results. Generally speaking, polar aprotic solvents are conducive to the nucleophilic substitution reaction. Selecting a suitable base can promote the formation of cyanoanions, thereby promoting the reaction to the right and obtaining the target product efficiently.
    Third, using metal-organic chemistry method. The reaction of metal-organic reagents with pyridine derivatives is used to construct carbon-cyanide bonds. For example, organolithium reagents, Grignard reagents, etc. are used to metallize the pyridine derivatives first, and then react with the cyanide source. This process needs to be carried out in an anhydrous and oxygen-free inert gas protective atmosphere to prevent the oxidation and hydrolysis of the metal reagents, ensure the smooth implementation of the reaction, and achieve the synthesis of 2-% nitrile-5-cyanopyridine.
    The above methods have their own advantages and disadvantages. In practical application, it is necessary to carefully select suitable synthesis methods according to specific circumstances, such as the availability of raw materials, cost considerations, and purity requirements of target products, in order to achieve efficient and economical synthesis goals.
    What are the physical properties of 2-chloro-5-cyanopyridine?
    2-%-5-alkyl valeraldehyde, which has the following physical properties:
    The outer layer is usually liquid, and under normal conditions, due to molecular forces and chemical properties, it is liquid-shaped. In terms of melting, the melting phase is low, because the degree of interaction between molecules and the like is limited, so that the energy required for solidification of the liquid is not high; and the boiling force is determined by the size of the molecular force, because the molecular force is non-molecular, so the boiling effect is also specific to the specific phase. The solubility of
    is specific, and the presence of a group (-OH) makes this substance have a certain solubility in water. Because the group can form a group of water molecules, it increases the strength of its water molecules. However, the molecule also contains a certain amount of carbon, which increases the hydrophobicity. Therefore, in non-soluble molecules such as benzene, there is also a certain dissolution direction, but the solubility of the phase is different in water. In terms of density, based on the composition and composition of its molecules, its density is similar to that of water, slightly larger or smaller than that of water. This property depends on the arrangement of molecules, atoms, and spaces. The amount of molecules and the proportion of the space determined the size of its density.
    In terms of durability, due to the fact that the molecular force is not large and has a certain durability, in the normal environment, it will slow down to the surrounding air. Its speed is affected by factors such as temperature and flow. The higher the temperature, the faster the flow speed, and the faster the flow rate.
    In addition, this substance may have a special taste. Due to the existence of specific molecules and functionalities, its smell may have a certain irritation or special aroma, and the interaction between molecules and olfactory receptors is caused. Therefore, the physical properties of 2-%-5-valeraldehyde are determined by its molecular properties and composition, and it shows the characteristics of phase release under different environmental conditions.
    What should be paid attention to when storing and transporting 2-chloro-5-cyanopyridine?
    For 2-alkane-5-alkylpyridine, there are three things to pay attention to when storing and transporting it.
    First environmental conditions. This compound likes a dry, cool and well-ventilated place. Cover a humid environment, it is easy to cause it to react with water vapor, or biochange, damaging its purity and performance. And under high temperature, this substance may increase activity, which may cause danger, so it is necessary to avoid high temperature, open flame and hot topic sources to prevent accidents.
    The second is packaging caution. It should be stored in a tightly sealed container with suitable material. If a glass bottle is used, it must be thick-walled and pressure-resistant to prevent it from being damaged; if a metal container is used, it should be checked to see if it fits with it. Outside the packaging, its name, characteristics and hazard warnings should be clearly marked, so that people who see it know its nature and avoid accidental touch.
    Furthermore, it is for personnel protection. Those who participate in storage and transportation must wear appropriate protective equipment. Wear goggles to protect the eyes from splashing liquid; wear protective clothing to protect the skin from contact with it; wear gas masks to prevent inhalation of its volatile gas. And when operating, follow the procedures and handle it with care to avoid leakage. In the event of leakage, immediately initiate emergency measures, evacuate the crowd, seal the scene, and choose the appropriate decontamination method according to its nature.
    All of these are essential for the storage and transportation of 2-alkane-5-alkylpyridine, and must be kept in mind to ensure safety.
    What is the market price of 2-chloro-5-cyanopyridine?
    Today there is 2-cyanopyridine 5-cyanopyridine, the market price of which I shall analyze in detail for you.
    However, the price of this chemical often changes due to many factors. First, the price of raw materials is the key. If the various raw materials required for the production of 2-cyanopyridine are difficult to obtain and the prices are different, the cost of this chemical will fluctuate accordingly. If the supply of raw materials is abundant and cheap, the cost of 2-cyanogen-5-cyanopyridine may be reduced, and its market price is expected to be reduced; conversely, if the raw materials are scarce and expensive, the cost will increase, and the price will also rise.
    Second, the market supply and demand situation has a great impact. If at a certain time and place, many industries have strong demand for 2-cyanogen-5-cyanopyridine, but the supply is limited, the so-called supply is in short supply, and its price will rise; conversely, if the demand is low, the supply is excessive, and the supply is oversupplied, the price will inevitably fall.
    Third, the production process and technical level are also closely related. Advanced production processes can improve production efficiency, reduce energy consumption and loss, which may reduce costs and make prices more competitive; if the process is backward, the efficiency is low, the cost increases, and the price is difficult to be close to the people.
    Fourth, policies and regulations and the market environment cannot be ignored. Environmental protection policies, trade policies, etc. in various places can have an impact on their production, transportation, and sales, which in turn affects prices. For example, strict environmental protection policies may cause production enterprises to increase environmental protection inputs, increasing costs and causing price changes. Therefore, in order to know the exact market price of 2-cyanopyridine, it is necessary to pay attention to the raw material market, supply and demand dynamics, technological development and policy changes in real time in order to be certain.