2 Chloro 5 Chloromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-chloro-5-(chloromethyl)pyridine

    Specifications

    HS Code

    114155

    Chemical Formula C6H5Cl2N
    Molecular Weight 162.016 g/mol
    Appearance Typically a colorless to light - yellow liquid
    Boiling Point Around 230 - 232 °C
    Density Approx. 1.36 g/cm³
    Solubility In Water Poorly soluble in water
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, and dichloromethane
    Flash Point Caution: Flammable, flash point values around 99 - 101 °C
    Odor May have a pungent, chlorinated odor
    Stability Stable under normal conditions but may react with strong oxidizing agents

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    Frequently Asked Questions

    As a leading 2-chloro-5-(chloromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-chloro-5- (chloromethyl) pyridine
    2-Chloro-5- (chloromethyl) pyridine, this is an organic compound with many unique physical properties.
    Its properties are colorless to light yellow liquid, which exists stably at room temperature and pressure. Looking at its color, it is pure color, without interference from variegated colors, like morning dew, clear and pure. Its smell is special, with a slight irritation, although it is not strong and pungent, it can still be perceived close to the fine smell.
    When it comes to solubility, this compound is soluble in many organic solvents, such as ethanol, ether, dichloromethane, etc., just like fish entering water and blending seamlessly. This property makes it easy to mix and react with other organic reagents in the field of organic synthesis, establishing a good platform for many chemical reactions.
    The boiling point is also one of its important physical properties. The boiling point is within a specific range. At this temperature, the compound changes from a liquid state to a gaseous state, just like breaking a cocoon into a butterfly. Its boiling point value is [specific value], which ensures that under specific conditions, it can be separated and purified by means of distillation.
    The melting point cannot be ignored either. The melting point is [specific value]. At this temperature, the compound changes from a solid state to a liquid state, just like ice and snow melting at the beginning, opening a new form. The characteristics of the melting point are of great significance for the storage and transportation of compounds, ensuring that they maintain a stable state under appropriate temperature conditions.
    In terms of density, 2-chloro-5- (chloromethyl) pyridine has a certain density, [specific density value], which makes it possible to separate it according to the density difference when mixed with other substances, such as stratification and other phenomena, to facilitate chemical production and experimental operation.
    In addition, its flash point is [specific flash point value], and the flash point is related to the safety of the compound. Users are reminded to pay attention to the source of ignition when handling the compound to prevent fire accidents, just like wearing a "seat belt" during use.
    The physical properties of 2-chloro-5- (chloromethyl) pyridine are interrelated, which together determine their application and treatment in the field of organic chemistry, and are of great significance in scientific research and industrial production.
    What is the main use of 2-chloro-5- (chloromethyl) pyridine?
    2-Chloro-5- (chloromethyl) pyridine is also an organic compound. It has a wide range of uses and is a key intermediate in the field of medicinal chemistry. It can be used to create a variety of drugs, such as some antibacterial drugs and drugs for the treatment of specific diseases. Due to its special chemical structure, it can participate in a variety of chemical reactions to build key parts of drug molecules.
    In the field of pesticide chemistry, it is also an important raw material. Pesticide products with insecticidal, bactericidal or herbicidal effects can be derived. By reacting with other chemicals, compounds that have targeted inhibition or killing effects on crop pests, pathogens or weeds can be shaped to help agricultural production and improve crop yield and quality.
    In the field of materials science, 2-chloro-5- (chloromethyl) pyridine is also used. Or it can be used to prepare special polymer materials, through its polymerization with specific monomers, giving the material unique properties, such as improving the material's heat resistance, chemical corrosion resistance, etc., to meet the stringent requirements of material properties in different industrial scenarios.
    To sum up, 2-chloro-5- (chloromethyl) pyridine plays an indispensable role in many important fields such as medicine, pesticides and materials science, and is of great significance to promote the development of related industries.
    What are the synthesis methods of 2-chloro-5- (chloromethyl) pyridine
    The synthesis method of 2-chloro-5- (chloromethyl) pyridine has been around for a long time, and the technology has changed with time. Today, several common methods are described in detail for your pleasure.
    One is to use pyridine derivatives as starting materials. Select a suitable pyridine compound and introduce chlorine atoms and chloromethyl groups at a specific position. First place the pyridine substrate in a suitable reaction vessel, and add a specific halogenating agent, such as a chlorine-containing halogenating agent. During the reaction, it is necessary to strictly control the temperature and observe the fluctuation of the temperature, just like understanding the changes of all things. The halogenating agent interacts with the pyridine substrate to make the chlorine atom fall precisely at the 2-position of the pyridine ring. This step requires delicate control of the reaction conditions, such as reaction time and reagent dosage. If there is a slight difference, it will be difficult to achieve the expected effect.
    After the 2-chloropyridine derivative is formed, chloromethyl is introduced. At this time, select a suitable chloromethylation reagent and make it blend with 2-chloropyridine derivatives in a suitable reaction environment. This process is like a carefully prepared chess game. The ratio of each reactant and the pH of the reaction need to be carefully considered. After this step, 2-chloro-5- (chloromethyl) pyridine can be obtained.
    Second, using other organic compounds as starting materials, pyridine rings are constructed through multi-step reactions, and target substituents are introduced at the same time. First, a number of simple organic compounds are used as cornerstones, and the prototype of pyridine rings is built through reactions such as condensation and cyclization. This process is like building a magnificent castle, and each step needs to be done steadily. When the pyridine ring begins to take shape, chlorine atoms and chloromethyl groups are introduced in sequence as in the previous method. Although this approach is complicated, if it is operated properly, it can be obtained efficiently.
    Third, with the help of catalytic reaction methods. Adding a specific catalyst to the reaction system, this catalyst is like a guide for chemical reactions, which can accelerate the reaction process and improve the selectivity of the reaction. With suitable starting materials and the help of catalysts, 2-chloro-5- (chloromethyl) pyridine is gradually generated through ingenious reaction paths. The choice of catalyst, the dosage and the optimization of reaction conditions are all key. It takes repeated experiments and insight into subtle changes to find the best reaction conditions and make the synthesis process smooth.
    The above synthesis methods have their own advantages. In practical applications, it is necessary to carefully choose according to specific needs, raw material availability and cost factors, etc., to achieve twice the result with half the effort.
    What to pay attention to when storing and transporting 2-chloro-5- (chloromethyl) pyridine
    2-Chloro-5- (chloromethyl) pyridine is an important intermediate in organic synthesis. During storage and transportation, many key matters need to be paid careful attention.
    Choose the first storage environment. This substance should be stored in a cool, dry and well-ventilated place. Because it is more sensitive to heat, high temperature is easy to decompose or cause other chemical reactions, so it is necessary to keep away from fire and heat sources to prevent accidents. The temperature of the warehouse should be maintained in an appropriate range, usually not exceeding 30 ° C. And it is easy to deteriorate in case of moisture, so the storage place must be kept dry and the humidity should not be too high.
    Furthermore, the material and seal of the storage container are extremely critical. Corrosion-resistant containers, such as glass or specific plastic materials, should be selected to avoid reaction with the container. At the same time, the container should be tightly sealed to prevent its volatilization and escape, and avoid contact with air to prevent oxidation and other reactions.
    When transporting, the packaging must be stable and reliable. Appropriate packaging materials should be used in accordance with relevant regulations to ensure that the packaging will not be damaged during transportation. The loading and unloading process should also be handled with care to prevent bumping and heavy pressure, so as not to cause material leakage due to package damage.
    The cleanliness and dryness of the transportation vehicle should not be ignored. If the transportation vehicle has transported other chemicals, it must be thoroughly cleaned to prevent the residual substances from reacting with 2-chloro-5- (chloromethyl) pyridine.
    In addition, transportation personnel also need to have professional knowledge and be familiar with the characteristics of the substance and emergency treatment methods. In the event of an unexpected situation such as a leak during transportation, they can take prompt and correct response measures, such as evacuating the crowd, isolating the scene, plugging and cleaning, etc., to minimize the harm.
    Storage and transportation of 2-chloro-5- (chloromethyl) pyridine requires comprehensive consideration of all factors and strict follow of relevant specifications and operating procedures to ensure safety and avoid accidents.
    What are the effects of 2-chloro-5- (chloromethyl) pyridine on the environment and human health?
    2-Chloro-5- (chloromethyl) pyridine is an organic compound. It may have various uses in industry, but it does have potential effects on the environment and human health.
    Discussing the impact on the environment, if this compound is released in the natural environment, its stability and persistence or accumulation. In soil, or hinder the growth and development of plant roots. Because of its chlorine atoms, under certain conditions, it may participate in chemical reactions to form harmful derivatives. It is in water bodies, or affects aquatic organisms. Such as fish, shellfish, etc., or due to exposure to this compound, physiological functions are damaged, resulting in reproduction, growth inhibition, and even death. And this compound migrates in the environment, or diffuses by water flow or wind, causing the scope of influence to expand.
    As for the impact on human health, inhalation of this compound through the respiratory tract, or irritation of respiratory mucosa, causing cough, asthma and other diseases. If the skin comes into contact with it, it may cause allergies and inflammation. Long-term exposure to this compound environment, according to research, may pose a risk of carcinogenesis. Because its chemical structure is active, or it interferes with the normal metabolic process of human cells, causing cell mutation, which in turn induces cancer. Or it affects the human nervous system, causing headache, dizziness, fatigue and other discomfort. Therefore, when producing and using 2-chloro-5- (chloromethyl) pyridine, it is necessary to adhere to safety procedures and properly dispose of waste to reduce its harm to the environment and human health, and to maintain ecological balance and human well-being.