2-Chloro-5-Chloromethyl pyridine 95%min

2-Chloro-5-chloromethylpyridine (content 95% min) has a wide range of uses. In the field of medicine, it is often used as a key intermediate to help synthesize a variety of specific drugs. Geinpyridine has a unique structure and can enhance the stability and biological activity of drugs in the construction of drug molecules. For example, when synthesizing specific antibacterial drugs, it can precisely introduce key groups, optimize the mechanism of action of the drug on bacteria, and improve the antibacterial efficacy.
In terms of pesticides, it is also an important raw material. High-efficiency insecticides, fungicides, etc. can be prepared. Because of its chlorine atom, it has interference effects on the nervous system and microbial metabolic pathways of insects. For example, the preparation of new pyridine insecticides can effectively kill pests, and is relatively friendly to the environment with low residues
In the chemical industry, it is used to synthesize functional materials. Pyridine ring and chloromethyl give the material unique properties, such as when synthesizing specific polymer materials, it can be used as a reactive monomer to improve the mechanical properties and thermal stability of the material. For example, in some special engineering plastics, the introduction of this structure can enhance its strength and weather resistance.
In addition, in organic synthesis research, it provides key structural units for researchers to help them explore new synthesis routes and compounds, and expands the boundaries of organic chemistry research, which is of great significance to promoting the development of chemistry.

2-Chloro-5-chloromethylpyridine, content 95% min. The physical properties of this substance are as follows:
Its appearance is mostly colorless to light yellow liquid, which exists stably at room temperature and pressure. The melting point is usually in a relatively low range, and the exact value varies slightly due to specific experimental conditions and impurities. The boiling point is relatively high, indicating that the intermolecular force is strong, and higher energy is required to transform it from liquid to gaseous.
This substance is slightly soluble in water, although it contains polar groups in its molecular structure, the overall hydrophobic part accounts for a large proportion. However, it is better soluble in a variety of organic solvents, such as ethanol, ether, dichloromethane, etc. This is due to the principle of similar miscibility. The polarity and molecular structure of organic solvents have a certain degree of compatibility with 2-chloro-5-chloromethylpyridine.
In terms of density, it is larger than water. If mixed with water, it will sink to the bottom. Its vapor pressure is relatively low, and its volatilization rate is relatively slow at room temperature. The refractive index also has a specific value, and this property can be used for identification and purity detection. The refractive index of 2-chloro-5-chloromethylpyridine with different purity is slightly different. In addition, it has a certain pungent odor, and safety measures such as ventilation should be taken during operation to prevent discomfort to the human body.

The preparation method of 2-chloro-5-chloromethylpyridine (content 95% min), although the ancient book "Tiangong Kaiwu" does not detail the method of this specific substance, it can be deduced according to chemical reasons.
Common method 1, using pyridine as the base, first introduces chlorine atoms at the 2nd position of the pyridine ring, and then introduces chloromethyl groups at the 5th position. For example, pyridine reacts with chlorine under specific conditions, controlling temperature, light, etc., so that the chlorine atom selectively replaces the hydrogen at the 2nd position to obtain 2-chloropyridine. Then 2-chloropyridine reacts with polyformaldehyde, hydrogen chloride and catalyst to introduce chloromethyl at the 5th position.
Second, a suitable pyridine derivative is used as the starting material. If there is a pyridine with a suitable substituent, after a multi-step reaction, the substituent is first modified to convert it into an active group that can introduce chloromethyl and chlorine atoms. After halogenation, substitution and other reactions, 2-chloro-5-chloromethylpyridine is gradually obtained.
The reaction process requires precise control of conditions, such as temperature. If it is too high, the side reaction will produce and the product will be impure; if it is too low, the reaction will be delayed. The proportion of reagents used should also be accurate, otherwise the yield will be affected. The choice of catalyst is also critical, and the appropriate one can accelerate the reaction and improve efficiency. And after each step of the reaction, it needs to be separated and purified to remove impurities and obtain high-purity 2-chloro-5-chloromethylpyridine.

2-Chloro-5-chloromethylpyridine, with a content of 95% min, the market price varies from time to time and is also affected by many factors. In the past, when the market changed, the price of this product often fluctuated with the trend of supply and demand and changes in manufacturing costs.
If you look at the past, when the raw materials are abundant, the manufacturing is smooth, and the number of people who need it is low, the price will often be lower. Because the stock of goods is in the market, the seller wants to sell it quickly, so he reduces the price to sell it. On the contrary, if the raw materials are scarce, the manufacturing is difficult, and there are many people who need it, the price will rise. For example, when the raw materials for the production of this drug are scarce, the labor cost of manufacturing has increased greatly, and the industries need this product urgently, the price will jump. < Br >
There is also market competition. If there are many people in the same industry, they all sell this product in order to compete for market profit, or they may reduce the price to attract customers. And when there is no semicolon, the right to set the price depends on their own hands, and the price may be higher.
As for the exact price today, it cannot be determined immediately. You need to visit various cities, consult various merchants, and observe the price of their recent transactions. Probably in the market of chemical raw materials, you can ask brokers and merchants to observe the market in detail before you can get the actual price. Or on the platform of market change, observe the listed price and transaction amount to push the current market price.

2-Chloro-5-chloromethylpyridine, content 95% min, this substance should pay attention to many matters during storage and transportation.
Its properties have certain chemical activity, and when stored, the first environment is dry. Because moisture is easy to cause its chemical reaction, resulting in quality deterioration. In the warehouse, it should be well ventilated and protected from direct sunlight. If it is heated or decomposes, it will endanger safety and quality.
Furthermore, it may be toxic and irritating. The storage place should be far away from the crowded place, and it is forbidden to eat, drink and smoke. When handling, operators must wear appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent contact with skin and eyes. If they accidentally touch it, they should quickly rinse with plenty of water and seek medical treatment.
When transporting, the packaging must be solid and reliable. Select containers that meet the transportation standards for hazardous chemicals, tightly sealed to prevent leakage. Transportation vehicles also need to be equipped with corresponding emergency treatment equipment and protective equipment for emergencies. Transportation route planning should avoid densely populated areas and environmentally sensitive places, and travel according to the specified route and time.
In addition, whether it is storage or transportation, detailed records should be kept, including quantity, warehousing or departure arrival time, etc., for traceability and supervision, to ensure the safety and order of the whole process.