2-chloro-5-(1,3-thiazol-2-yl)pyridine

2-Chloro-5- (1,3-thiazole-2-yl) pyridine, an organic compound, has important uses in many fields.
First, in the field of medicinal chemistry, its use is quite critical. Many drug development often use this as a key intermediate. Due to the unique biological activity of thiazole and pyridine structures, 2-chloro-5- (1,3-thiazole-2-yl) pyridine can be chemically modified to construct structures that interact with specific biological targets. For example, for some disease-related enzymes or receptors, derivatives can be used to create compounds with specific pharmacological activities, which are expected to become new therapeutic drugs, such as anti-cancer, antibacterial or anti-inflammatory drugs.
Second, in the field of pesticides, this compound also has important applications. Pyridine and thiazole structures often show good biological activity and can be used in the development of pesticides, fungicides and other pesticide products. 2-Chloro-5- (1,3-thiazole-2-yl) pyridine can be converted into a pesticide component with high inhibition or killing effect on crop pests or pathogens through an appropriate synthetic path, and because of its unique structure, it may have the advantages of environmental friendliness, low toxicity and high efficiency, which is of great significance to the sustainable development of agriculture.
Furthermore, in the field of materials science, 2-chloro-5- (1,3-thiazole-2-yl) pyridine can also play a role. Organic semiconductor materials have attracted much attention in recent years, and compounds containing nitrogen and sulfur heterocycles often have unique electrical and optical properties in this field. This compound may be used as a building block to participate in the synthesis of organic semiconductor materials, and be used in organic Light Emitting Diodes (OLEDs), organic field effect transistors (OFETs) and other devices, contributing to the development of materials science.
In summary, 2-chloro-5- (1,3-thiazole-2-yl) pyridine is widely used in the fields of medicine, pesticides and materials science, and is of great significance to promote technological progress and innovation in various fields.

2-Chloro-5- (1,3-thiazole-2-yl) pyridine, this is an organic compound. Its physical properties are quite important and affect many chemical application fields.
Let's talk about the appearance first. Under normal temperature and pressure, it is mostly white to light yellow crystalline powder. This form is easy to store and process, and is easy to measure and transfer in many chemical operations. Looking at its color, this white to light yellow is also its significant appearance characteristic, providing an intuitive basis for distinguishing this substance.
Besides the melting point, it has been experimentally determined to be between 110-114 ° C. The characteristics of the melting point are of great significance for its state transition during heating. When the temperature rises near the melting point, the compound gradually changes from a solid state to a liquid state, which is crucial in industrial processes such as purification and molding.
Its solubility cannot be ignored. In common organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), etc., it exhibits good solubility. In dichloromethane, it can quickly disperse and dissolve to form a uniform solution, which is conducive to participating in various organic synthesis reactions. However, its solubility in water is poor, which is related to the large proportion of hydrophobic groups in its molecular structure. This solubility difference needs to be carefully considered when separating, purifying and constructing the reaction system.
In addition, the stability of this compound is worthy of attention. In normal temperature and humidity environments, it has certain stability. However, if it encounters extreme conditions such as strong acid, strong alkali or high temperature, its molecular structure may be damaged, chemical reactions will occur, and its chemical properties will be changed. Therefore, during storage and use, it is necessary to pay attention to the influence of environmental factors to ensure the stability of its physical properties and ensure the smooth progress of related chemical processes.

The synthesis method of 2-chloro-5- (1,3-thiazole-2-yl) pyridine, although the ancient book "Tiangong Kaiwu" does not contain this specific compound synthesis method, it can be deduced from the ancient chemical process idea.
To combine this substance, you can first find the raw material containing the structure of pyridine and thiazole. Or choose a pyridine derivative, which introduces chlorine atoms at the second position of the pyridine ring. This step can imitate the ancient halogenation method. With appropriate halogenating agents, temperature control, time and other conditions, the chlorine atom can be replaced by the second hydrogen.
The thiazole part is obtained according to the ancient concept of organic synthesis, or by condensation of raw materials containing sulfur and nitrogen. Later, the chloropyridine-containing derivatives are reacted with thiazole intermediates, which can be formed by ancient bonding methods, such as nucleophilic substitution. Select an appropriate base as a catalyst and promote the bonding of the two in an organic solvent to obtain the target product 2-chloro-5- (1,3-thiazole-2-yl) pyridine. When operating, pay attention to the reaction conditions of each step, and control the ancient process to improve the yield and purity. Although the ancient method is not fully integrated with modern organic synthesis, its concept can inspire today's people to explore the way of synthesis.

The price of 2-chloro-5- (1,3-thiazole-2-yl) pyridine in the market is difficult to determine. This is due to the influence of various factors, which makes its price fluctuate.
First, the price of raw materials has a lot to do with it. The preparation of 2-chloro-5- (1,3-thiazole-2-yl) pyridine requires specific raw materials. If the price of raw materials rises or falls, the price of the product will also become easier. If raw materials are rare and difficult to obtain, their price must be high, and the product is also expensive; if the raw materials are abundant, the price may be slightly reduced.
Second, the simplicity of the process is related to the cost and the price. If the preparation method is difficult, it requires exquisite equipment and high-skilled craftsmen, and it takes a long time, the cost will increase, and the price between the cities will be high; if the process is simple, the cost will be reduced and the price may be close to the people.
Third, the supply and demand of the city is the key. If there are many people who want it, the supply will be small. The so-called "rare things are precious", the price will rise; if the supply exceeds the demand, the merchants will sell their goods or reduce their prices to compete for the market.
Fourth, the difference in regions also makes the price different. In different places, taxes and transportation fees vary, all of which add to the cost and make the price different. In distant places, transportation costs are high, and the price may be higher than in the vicinity.
Basically speaking, the price is in the market or in the range of tens to hundreds of yuan per kilogram. However, this is only an approximate number, and the actual price should be determined according to changes in market conditions and the amount of purchase. To know the exact price, you can consult the chemical raw material supplier, or check the price information of the chemical product trading platform to get an accurate number.

2-Chloro-5- (1,3-thiazole-2-yl) pyridine, this is an organic compound. Its storage conditions are extremely critical, related to the stability and quality of the substance.
To view the characteristics of this compound, it is necessary to avoid moisture, because moisture is easy to cause its hydrolysis or other adverse reactions, resulting in its deterioration. Therefore, it is appropriate to store in a dry place, and the humidity of the warehouse should be controlled at a low level, such as the relative humidity should not exceed 60%.
Furthermore, temperature is also an important factor. High temperature can accelerate the rate of chemical reactions, or cause changes such as decomposition and polymerization. This compound should be stored in a cool place, preferably at a temperature of 2-8 ° C. Low temperature environment can reduce its molecular activity and reduce the possibility of adverse reactions.
Light exposure should not be ignored. Many organic compounds are sensitive to light, and light or photochemical reactions can damage their structure and properties. 2-Chloro-5- (1,3-thiazole-2-yl) pyridine should be stored in the dark. It can be stored in a brown bottle or a container with a light-shielding coating in a dark place to prevent direct light.
In addition, this compound may have certain toxicity and danger. When storing, it must be stored separately from oxidants, acids, bases, etc., to prevent dangerous interactions. The storage area should be well ventilated to disperse the volatile gas that may leak in time and reduce the safety risk. And there should be obvious warning signs to indicate its danger, so that personnel can operate and manage it carefully. In this way, the storage of 2-chloro-5- (1,3-thiazole-2-yl) pyridine is safe and stable.