2 Chloro 4 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-4-(trifluoromethyl)pyridine

    Specifications

    HS Code

    423270

    Chemical Formula C6H3ClF3N
    Molecular Weight 181.54
    Appearance Colorless to light yellow liquid
    Boiling Point 152 - 154 °C
    Melting Point N/A
    Density 1.398 g/mL at 25 °C
    Flash Point 45 °C
    Solubility In Water Insoluble
    Vapor Pressure N/A
    Odor Characteristic odor

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    General Information
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    Frequently Asked Questions

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    What are the main uses of 2-chloro-4- (trifluoromethyl) pyridine?
    2-% -4- (triethylmethyl) pyridine, which is a valuable chemical compound, its main use involves many domains.
    In the field of synthesis, it often plays an important role in synthesis. Due to the specific chemical activity of the chemical compound, it can be composed of a series of anti-bacterial and ingeniously bioactive molecules. For example, in the development of some antibacterial compounds, 2-% -4- (triethylmethyl) pyridine can be used as a starting material, and the refined chemical modification, such as acetylation and acetylation, can gradually build the molecules that meet the antibacterial action, providing an indispensable foundation for the research.
    In the field of materials science, it also plays an important role. In the synthetic exploration of high-performance materials, 2-% -4- (triethylmethyl) pyridine can be used as a copolymer. With the combination of nitrogen atoms and aromatics in its molecules, it can improve the properties of the material. Similarly, in the modification engineering of some polymer materials, the introduction of this compound can improve the resistance, mechanical properties and other properties of the material.
    In addition, in the chemical catalysis, 2-% -4- (triethylmethyl) pyridine can be used as a ligand to form a high-efficiency catalyst. This catalyst exhibits excellent catalytic activity in a wide range of reactions, such as chemical reactions, even reactions, etc. Taking the even reaction of catalysis as an example, the 2-% -4- (triethylmethyl) pyridine-derived formulation can effectively deposit the active center, promote the activation of the reaction substrate, and greatly improve the reaction efficiency.
    What are the physical properties of 2-chloro-4- (trifluoromethyl) pyridine?
    2-% -4- (triethylmethyl) pyridine, which has a general physical property. Under normal conditions, it is a liquid substance, and the color is transparent, like clear water, which is a special color.
    Its smell is specific, and it emits a stimulating smell. The smell can make the nasal cavity feel it. If the amount is inhaled, it may not feel good.
    In terms of boiling, its boiling is at a certain degree of temperature, which is determined by its transformation. With the value of boiling, it is not good, but due to the influence of many factors such as the amount of water, or there is a slight wave.
    Furthermore, its density is also one of the important physical properties. In comparison with water, its density may vary. This density characteristic is crucial in the operation and workmanship of various materials, and can affect its distribution in mixtures.
    In terms of solubility, it can be soluble in some soluble materials, but its solubility in water has a certain limit. This solubility characteristic depends on the interaction of its molecules.
    In addition, the solubility of 2-% -4- (triethylmethyl) pyridine cannot be ignored. Under certain circumstances, it can be reduced from liquid and dispersed in the surrounding air.
    Therefore, the physical properties of 2-% -4- (triethyl) pyridine, such as color, taste, boiling quality, density, solubility, and solubility, etc., are the basis for in-depth understanding of this substance and its application in the related field.
    What are the chemical properties of 2-chloro-4- (trifluoromethyl) pyridine?
    2-% -4- (triethylmethyl) pyridine is a special chemical compound, and its chemical properties are of great importance for investigation. The atom of this compound is located in a specific location, and its integrity is deeply affected.
    In other words, the atom of the second position may be acidic due to its chemical environment. Under suitable conditions, this atom may be taken, and it can be used for multiple reactions, such as nuclear substitution antibodies, etc. In this reaction, the atom can be removed from the formed atom, or it can be used as a nucleus to attack other positive atoms or groups.
    The (triethyl) group of the fourth position is also an important property of this compound. The existence of this group affects the molecular sub-cloud and the space of the molecule. Because of the large substituent group, it generates the space resistance effect. In some antibodies, the space resistance or the reaction process is caused, so that the reaction occurs near the location; however, because of its existence, it may also cause the reaction to behave in a specific direction, such as in other locations.
    Furthermore, the pyridine of this compound also has its inherent properties. Pyridine has a certain aromaticity, which makes it phase-fixed. However, the substituent group on the matrix changes the density of the sub-cloud, which affects its substitution and nucleus substitution activities. Therefore, the chemical properties of 2-% -4- (triethylmethyl) pyridine are affected by the interaction of each substituent. In the field of synthesis or with specific applications, further research is needed to clarify its properties.
    What are the synthesis methods of 2-chloro-4- (trifluoromethyl) pyridine?
    To prepare 2-cyanogen-4- (trifluoromethyl) pyridine, the method is as follows:
    First, a suitable pyridine derivative is used as the starting material. After halogenation, halogen atoms are introduced at a specific position in the pyridine ring. This process requires careful selection of halogenated reagents and reaction conditions to achieve the purpose of precise positioning. Then, the halogenated pyridine derivative undergoes a nucleophilic substitution reaction with the cyanide reagent, and the halogen atom is replaced by a cyanide group to form a cyanide-containing pyridine intermediate. Finally, the introduction of trifluoromethyl is achieved by means of a specific fluorinated reagent. In this step, the activity and selectivity of the fluorinated reagent are crucial, and the reaction parameters need to be carefully adjusted to ensure that the trifluoromethyl is accurately connected to the target
    Second, another approach can be found. First, a pyridine skeleton containing trifluoromethyl is constructed, and trifluoromethyl is introduced into the parent structure of the pyridine through clever design of the reaction route. Subsequently, the pyridine ring is modified, and the cyanyl group is introduced at a suitable check point through a series of reactions. In this process, each step of the reaction needs to be carefully controlled, considering the feasibility of the reaction, the yield and the influence of side reactions. For example, the choice of reaction solvent, the control of temperature, and the use of catalyst all have a significant impact on the reaction process and product purity. Reasonable planning is required between each step of the reaction to ensure that the product of the previous step can be successfully used in the subsequent reaction, and the formation of impurities is minimized, so as to improve the quality and yield of the final product 2-cyano- 4 - (trifluoromethyl) pyridine.
    What are the precautions for storing and transporting 2-chloro-4- (trifluoromethyl) pyridine?
    In the storage of 2-% -4- (triethylmethyl) pyridine, it is necessary to pay attention to the general situation. Its performance is not active, and it is important to take it from the first environment. If it is placed in a place that is dry and well-connected, it must not be exposed to direct sunlight, or it may be modified due to light induction, so that its quantity is low. And it has a certain degree of stability. It is necessary to be dense and stored in order to prevent dispersion, cause the content to be low, and also prevent the escape from being tired in the environment and inducing a lot of emotions.
    Furthermore, the degree of control is essential. It is advisable to maintain the degree of determination and avoid the situation of intense waves. If the temperature is high, or the reaction speed is accelerated, and the decomposition and polymerization are undesirable. If the temperature is low, it may cause material change, affecting its original properties.
    If it is high, the packaging must be solid and reliable. The appropriate packaging material can effectively resist the vibration and collision on the way, and prevent the package from breaking and causing the material to be exposed. And it should be operated according to the phase of the dangerous chemical products, and the grid should be warned, so that the people can clearly understand its dangerous characteristics and take preventive measures.
    In addition, 2-% -4- (triethylmethyl) pyridine or some other substances do not react strongly, so they must avoid the combination of oxidizing substances, acids, and other substances in the storage, in order to prevent them from being reversed and endangering human safety and environmental safety. All this is necessary for the storage of 2-% -4- (triethylmethyl) pyridine, and there should be no slack.