2 Chloro 4 Methyl 5 Pyridinecarbonitrile
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-4-methyl-5-pyridinecarbonitrile

    Specifications

    HS Code

    147301

    Chemical Formula C7H5ClN2
    Molecular Weight 152.58
    Appearance Solid (usually)
    Melting Point Data may vary, needs experimental determination
    Boiling Point Data may vary, needs experimental determination
    Solubility In Water Low solubility (organic nitrile properties suggest poor water solubility)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Density Data may vary, needs experimental determination
    Flash Point Data may vary, needs experimental determination
    Vapor Pressure Low (due to its solid state at normal conditions)

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    General Information
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    Frequently Asked Questions

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    What are the main uses of 2-Chloro-4-methyl-5-pyridinecarbonitrile?
    2-Chloro-4-methyl-5-pyridinitrile, this is an organic compound. It has a wide range of uses in the field of medicine, and can be used as a key intermediate to help synthesize a variety of drugs. In the process of drug development, through specific chemical reactions, the compound is used as the starting material to carefully construct molecular structures with specific biological activities, so as to provide effective drugs for disease treatment.
    In the field of pesticide manufacturing, 2-chloro-4-methyl-5-pyridinitrile also plays an important role. Through a series of transformations, pesticide products with insecticidal, bactericidal or weeding effects can be prepared. These pesticides can effectively protect crops from pests and diseases, and improve crop yield and quality.
    In addition, in the field of materials science, they may be able to participate in the synthesis of functional materials. With their special chemical structure, they endow materials with unique properties such as optics and electricity to meet the needs of special materials in different fields. For example, in the preparation of some organic photoelectric materials, it may be used as a key component, affecting the photoelectric conversion efficiency and other properties of the material.
    What are 2-Chloro-4-methyl-5-pyridinecarbonitrile synthesis methods?
    To prepare 2-chloro-4-methyl-5-pyridineformonitrile, various synthesis methods are often followed. First, it can be started from the corresponding pyridine derivative. Choose the appropriate 4-methyl-5-pyridineformonitrile and treat it with chlorine reagents. Common chlorine reagents, such as thionyl chloride, phosphorus oxychloride, etc. Under suitable reaction conditions, such as in an appropriate solvent, control the temperature and reaction time, so that the chlorine atom replaces the hydrogen at a specific position to obtain the target product. This process requires attention to the influence of the amount of reagent and the reaction environment to increase the yield and purity of the product.
    Second, the pyridine structure can be constructed from the raw material containing the pyridine ring, and chlorine, methyl and cyanyl groups can be introduced at the same time. For example, with suitable nitrogen and carbon-containing raw materials, through a series of reactions such as condensation and cyclization, the pyridine ring is first formed, and then chlorine atoms, methyl and cyanyl are introduced in specific steps. When designing the reaction steps in this path, the order and conditions of each step must be carefully planned. The reaction steps must be carried out smoothly, and the excessive occurrence of side reactions should be avoided, resulting in complex and difficult separation of the product.
    Or start from other compounds that can be derived into the pyridine structure, and gradually add the required functional groups through multi-step transformation. All these methods require fine regulation of reaction conditions, making good use of various organic synthesis techniques, and carefully selecting the best synthesis path according to factors such as raw material availability, cost consideration, and reaction difficulty, in order to efficiently prepare 2-chloro-4-methyl-5-pyridineformonitrile.
    What are the physical properties of 2-Chloro-4-methyl-5-pyridinecarbonitrile?
    2-Chloro-4-methyl-5-pyridinecarbonitrile is one of the organic compounds. Its physical properties are quite elusive.
    Looking at its appearance, it often takes the form of white to off-white crystalline powder. This form is quite common in many organic compounds. The fine powder state is easy to participate in various chemical reactions. Due to its large surface area, it is more fully contacted with other reagents.
    As for the melting point, it is about a specific temperature range. This property is crucial in the identification and purification of compounds. Accurate determination of the melting point can help identify the purity of the substance. If the purity is high, the melting point range is relatively narrow; if it contains impurities, the melting point may be offset and the range becomes wider.
    Solubility is also a key physical property. It exhibits a certain solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), etc. In dichloromethane, because its molecular structure matches the polarity of dichloromethane, it can be well dispersed and dissolved. This solubility provides a basis for the selection of reaction solvents in organic synthesis, which is convenient for carrying out reactions in homogeneous systems and improving reaction efficiency and controllability.
    Density is also a property that cannot be ignored. Although the specific value needs to be accurately measured, the characteristics of its density are related to the distribution state of the substance in the mixed system, and affect the stratification and flow behavior of the substance during the liquid-liquid reaction or separation process.
    In addition, the stability of the compound also belongs to the category of physical properties. Under normal temperature and pressure and without special chemical environment interference, its chemical structure is relatively stable, and it is not easy to spontaneously decompose or other violent chemical changes. This stability provides convenience for its storage and transportation. It only needs to follow the storage conditions of conventional organic compounds and place it in a dry and cool place to avoid contact with strong oxidants, strong acids and bases and other active substances.
    What are the chemical properties of 2-Chloro-4-methyl-5-pyridinecarbonitrile?
    2-Chloro-4-methyl-5-pyridinecarbonitrile is a kind of organic compound. It has specific chemical properties, which are related to the interaction and reactivity of each atom in its structure.
    From the perspective of nucleophilic substitution reaction, the activity of chlorine atoms in this compound is quite good. Due to its electronegativity difference, the carbon-chlorine bond is polar, and chlorine is easily replaced by nucleophilic reagents. In case of reagents containing hydroxyl groups, amino groups and other nucleophilic groups, chlorine atoms may be replaced to derive new compounds. This property can be used to construct various pyridine derivatives in organic synthesis.
    Its cyano group also has significant chemical properties. The cyanyl group can undergo hydrolysis reaction, and under acidic or alkaline conditions, it can be gradually converted into carboxyl groups, amide groups, etc. In acidic media, the cyanyl group is hydrolyzed into amides, which can be further hydrolyzed into carboxylic acids; under alkaline conditions, although the hydrolysis process is different, the corresponding carboxylic salts and other products can be obtained in the end.
    Furthermore, although the methyl group of this compound is relatively stable, under certain conditions, such as the action of strong oxidants or the reaction initiated by free radicals, the methyl group may be oxidized to form derivatives such as alcohols, aldodes or carboxylic acids.
    2-chloro-4-methyl-5-pyridylmethanonitrile exhibits a variety of chemical reactivity due to the presence of chlorine atoms, cyanyl groups and methyl groups in the structure, and has important application value in the field of organic synthesis. Various complex and biologically active or functional organic molecules can be constructed through different reaction pathways.
    What are the precautions in storage and transportation of 2-Chloro-4-methyl-5-pyridinecarbonitrile?
    2-Chloro-4-methyl-5-pyridineformonitrile is an important chemical substance. When storing and transporting, many matters need to be paid attention to.
    First words storage. This substance should be placed in a cool, dry and well-ventilated place. In a cool place, to prevent high temperature from changing its properties or causing chemical reactions; in a dry place, to avoid moisture, edge water can react with many chemicals and cause it to deteriorate; in a well-ventilated place, it can dissipate harmful gases that may be generated and prevent gas accumulation from causing danger. Keep away from fire and heat sources. Open flames and high temperatures can cause it to burn or even explode, and should not be ignored. It should be stored separately from oxidants, acids, alkalis, etc. Due to the chemical activity of the substance, contact with the above-mentioned substances, or react violently, which will damage safety.
    Times and transportation. Before transportation, be sure to ensure that the packaging is complete and sealed to prevent its leakage. Leakage not only causes material loss, but also may pollute the environment and endanger personnel. During transportation, ensure that the container does not collapse, fall or damage. Transportation vehicles should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In case of emergency, they can respond in time. And when transportation, they should follow the prescribed route and do not stop in densely populated areas and residential areas to avoid leakage or accidents that endanger many people.
    In conclusion, the storage and transportation of 2-chloro-4-methyl-5-pyridineformonitrile is related to safety and quality, and all aspects need to be treated with caution and carried out in accordance with regulations to ensure safety.