2 Chloro 4 Iodo 3 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-CHLORO-4-IODO-3-METHYLPYRIDINE

    Specifications

    HS Code

    599247

    Name 2-CHLORO-4-IODO-3-METHYLPYRIDINE
    Molecular Formula C6H5ClIN
    Molecular Weight 271.47
    Appearance Solid (likely)

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    General Information
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    Frequently Asked Questions

    As a leading 2-CHLORO-4-IODO-3-METHYLPYRIDINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-CHLORO-4-IODO-3-METHYLPYRIDINE?
    2-Chloro-4-iodine-3-methylpyridine, this is an organic heterocyclic compound with unique physical properties. It is mostly solid at room temperature, and the structure is stable due to strong intermolecular forces. Looking at its color state, it is often white to light yellow crystalline powder, fine texture, dry to the touch.
    Melting point is about [X] ° C. This value is critical, because the melting point reflects the size of intermolecular forces and lattice stability. When heated to the melting point, the molecule can overcome the force, the lattice disintegrates, and the substance changes from solid to liquid.
    The boiling point is the temperature when the substance is gasified, and the boiling point of 2-chloro-4-iodine-3-methylpyridine is about [X] ° C. The boiling point is related to the molecular polarity and relative molecular weight. The relative molecular weight of the substance is large, and the molecular polarity enhances the intermolecular force, resulting in a higher boiling point.
    Solubility is also an important property. It is slightly soluble in water, because its molecular polarity is very different from that of water, and it is difficult for water to overcome the intermolecular force to disperse it. However, it has good solubility in organic solvents, such as ethanol, ether, and dichloromethane. Due to the principle of similar miscibility, organic solvents match the intermolecular force of the substance and are mutually soluble.
    In addition, its density is about [X] g/cm ³, and the density reflects the mass per unit volume, which is of great significance for determining its position in the mixture and the separation method.
    These physical properties of 2-chloro-4-iodine-3-methylpyridine have far-reaching implications for its application in organic synthesis, drug development and other fields. Understanding these properties can make a reasonable choice of operating conditions and realize its effective utilization and transformation.
    What are the chemical properties of 2-CHLORO-4-IODO-3-METHYLPYRIDINE?
    2-Chloro-4-iodine-3-methylpyridine is one of the organic compounds. Its chemical properties are unique and valuable for investigation.
    From the general view of halogenated pyridine, this compound contains chlorine and iodine dihalogen atoms. Chlorine and iodine atoms have their own characteristics in chemical reactions due to electronegativity differences. Chlorine atoms have moderate activity and can participate in nucleophilic substitution reactions. If they encounter nucleophilic reagents, they can be replaced by them to form new derivatives. There are many kinds of nucleophilic reagents, such as alkoxides and amines, which can react with them.
    Although the iodine atom is larger than the chlorine atom, it has a higher tendency to leave. Under appropriate conditions, it is easy to break away from the pyridine ring, providing an offensive check point for nucleophiles. Especially in basic or catalyst environments, the departure of iodine atoms is more likely to occur, which in turn triggers subsequent reaction processes.
    Furthermore, the methyl group on the pyridine ring is an electron donor group, which can affect the distribution of electron clouds on the ring. It can increase the electron cloud density of the pyridine ring, which affects the reactivity of halogen atoms to a certain extent. In the electrophilic substitution reaction, the positioning effect of methyl groups cannot be ignored, which can guide electrophilic reagents to attack specific positions on the pyridine ring.
    In addition, the stability of 2-chloro-4-iodine-3-methylpyridine is also affected by molecular structure. The steric hindrance effect between halogen atoms and methyl groups plays a role in their chemical properties and reactivity. Spatial hindrance may prevent some reagents from approaching the reaction check point, change the reaction rate, or affect the selectivity of reaction products.
    This compound is widely used in the field of organic synthesis due to its unique chemical properties. It can be used as a key intermediate for the preparation of organic molecules with specific functions. It has potential applications in pharmaceutical chemistry, materials science and other fields.
    What are the main uses of 2-CHLORO-4-IODO-3-METHYLPYRIDINE?
    2-Chloro-4-iodine-3-methylpyridine is also an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry to help the creation of new drugs. Due to its unique structure, it can participate in a variety of chemical reactions. Through various synthetic pathways, molecular structures with specific biological activities can be constructed, which is of great significance for the development of new drugs.
    In the field of pesticide chemistry, it is also an important raw material. Based on this, a variety of pesticides can be prepared through a series of reactions, such as insecticides, bactericides and herbicides. With its chemical properties, such pesticides have significant control effects on specific pests, bacteria or weeds, which helps to improve crop yield and quality.
    In the field of materials science, 2-chloro-4-iodine-3-methylpyridine is also useful. It can participate in the preparation of special functional materials, such as optoelectronic materials. Due to its specific chemical groups, it can endow materials with unique optoelectronic properties, which may have potential applications in the manufacture of optoelectronic devices.
    In addition, in organic synthetic chemistry, as a reaction substrate, it can react with many reagents such as nucleophilic substitution and coupling, providing an effective way to construct complex organic molecular structures and promoting the development of organic synthetic chemistry. Its applications in different fields are all derived from its own unique chemical structure and properties, providing assistance for the development of various fields.
    What are 2-CHLORO-4-IODO-3-METHYLPYRIDINE synthesis methods?
    Fu 2 - CHLORO - 4 - IODO - 3 - METHYLPYRIDINE is an organic compound. The method of synthesis can be followed in many ways.
    First, it can be started from a pyridine derivative. The methyl group is introduced at a specific position in the pyridine ring, which can be achieved by a suitable alkylation reaction. If pyridine is used as a raw material, in the presence of a base, it can be reacted with methylating reagents (such as iodomethane, etc.) to introduce methyl groups into the pyridine ring to obtain 3-methylpyridine.
    Then, 3-methylpyridine is halogenated. Chlorine atoms are introduced first, and suitable chlorination reagents, such as N-chlorosuccinimide (NCS), can be selected. Under appropriate reaction conditions, such as light or the presence of a specific catalyst, chlorine atoms can be introduced at specific positions in the pyridine ring to obtain 2-chloro-3-methylpyridine.
    Finally, iodine atoms are introduced. Usually, iodizing reagents, such as potassium iodide, are combined with appropriate oxidants (such as hydrogen peroxide, etc.). Under suitable solvents and reaction conditions, 2-chloro-3-methylpyridine is iodized, and then 2-CHLORO-4-IODO-3-METHYLPYRIDINE is obtained.
    Second, it can also be converted from other nitrogen-containing heterocyclic compounds through a multi-step reaction. First, the starting material is structurally modified to construct a pyridine ring and introduce methyl groups, followed by the introduction of chlorine atoms and iodine atoms. This process requires fine regulation of reaction conditions, such as temperature, pH, and reactant ratio, according to the characteristics of each step, in order to achieve the expected synthesis target.
    In short, the method of synthesizing 2-CHLORO-4-IODO-3-METHYLPYRIDINE should be used according to the actual situation, weighing the availability of raw materials, the difficulty of reaction, cost-effectiveness and many other factors, and choosing the best one.
    2-CHLORO-4-IODO-3-METHYLPYRIDINE What are the precautions in storage and transportation?
    2-Chloro-4-iodine-3-methylpyridine is an organic compound, and many things must be paid attention to when storing and transporting.
    For storage, first, it should be placed in a cool and dry place. Because it is sensitive to heat, high temperature is easy to cause decomposition reactions, which in turn affects the quality. If it is in a humid environment, moisture may interact with the compound, causing adverse chemical reactions such as hydrolysis. Second, ensure that the storage place is well ventilated. This compound or volatile gas with a certain irritating odor can be dispersed in time with good ventilation to avoid local accumulation and reduce latent risk. Third, keep away from fire sources and oxidants. The organic compound is flammable, and it is easy to burn when exposed to open flames or hot topics, and the oxidizer will react violently with it, causing combustion or even explosion. Fourth, it should be stored in a sealed container to prevent contact with air. Oxygen in the air may oxidize it, resulting in changes in composition.
    When transporting, first of all, the packaging must be tight. Appropriate packaging materials, such as strong plastic drums or glass bottles, should be used, and properly fixed to prevent damage to the packaging due to collisions and bumps during transportation, resulting in leakage. Second, the means of transportation should be kept clean and dry to avoid other impurities from mixing. Furthermore, transporters should be familiar with the characteristics of the compound and emergency treatment methods. In the event of an unexpected situation such as a leak, it can be dealt with quickly and correctly to prevent the expansion of the hazard.
    In addition, whether it is storage or transportation, it is necessary to strictly follow relevant laws, regulations and safety standards, do a good job of marking and recording, and clearly label the name, characteristics, hazards and other information of the item, so that relevant personnel can keep abreast of the situation and ensure the safety of the entire process.