2 Chloro 3 Pyrrol 1 Ylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-3-pyrrol-1-ylpyridine

    Specifications

    HS Code

    279870

    Chemical Formula C9H8ClN3
    Molar Mass 193.63 g/mol
    Appearance Solid (Typical for this type of compound, exact color may vary)
    Solubility In Water Low (organic compounds with such structure often have low water solubility)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (due to its organic nature)
    Vapor Pressure Low (typical for non - volatile solid organic compounds)

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    General Information
    Where to Buy 2-Chloro-3-pyrrol-1-ylpyridine in China?
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    Frequently Asked Questions

    As a leading 2-Chloro-3-pyrrol-1-ylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Chloro-3-pyrrol-1-ylpyridine?
    2-Chloro-3-pyrrole-1-ylpyridine is one of the organic compounds. It has a wide range of uses and is often a key intermediate in the synthesis of many drugs in the field of medicinal chemistry. The structure of geinpyridine and pyrrole gives this compound unique chemical activity and pharmacological properties, which can participate in various chemical reactions and help build complex drug molecular structures.
    In the field of materials science, it also has its uses. It can be used as a raw material for the preparation of specific functional materials. Because its structure can introduce special electronic properties and stability to materials, it may have potential applications in optoelectronic materials, such as affecting the electrical conductivity and optical properties of materials.
    Furthermore, in the field of pesticide chemistry, it may play an important role. With its unique chemical structure, it may show inhibitory or killing effects on some pests and pathogens, and then be used to create new pesticides, providing assistance for agricultural pest control.
    In short, 2-chloro-3-pyrrole-1-ylpyridine has important uses in many fields such as medicine, materials, and pesticides, and is of great significance to the development of related industries and scientific research.
    What are the physical properties of 2-Chloro-3-pyrrol-1-ylpyridine?
    2-Chloro-3-pyrrole-1-ylpyridine, this is an organic compound. Its physical properties, let me talk about them one by one.
    Looking at its properties, under normal temperature and pressure, it usually appears solid. Due to the moderate force between molecules, it maintains a solid state under normal circumstances. Its melting point is about a specific value, but it varies slightly due to factors such as the amount of impurities. The characteristics of this melting point are crucial in the identification and purification of this substance, and its purity can be judged by means of melting point measurement.
    When it comes to solubility, it shows a certain solubility in organic solvents such as ethanol and acetone. This is because the molecular structure of the compound and the organic solvent molecules can form interactions such as van der Waals forces, hydrogen bonds, etc., so it is soluble. However, in water, the solubility is relatively poor, and the molecular polarity matches the polarity of water are not ideal.
    When it comes to density, it has its specific value. Compared with water, it is heavier or lighter. This density characteristic is important in separation, extraction and other operations. If its density is greater than that of water, it will be in the lower layer when delaminating; otherwise, it will be in the upper layer, so that it can achieve preliminary separation from other substances.
    Its volatility is low and it is not easy to disperse into the air at room temperature. This is because the intermolecular force is strong, and it is difficult for molecules to break free from the binding and escape the system. This property makes it unnecessary to worry too much about its rapid volatilization during storage and use, causing loss or safety issues.
    In addition, its stability is acceptable under normal conditions. However, in case of extreme conditions such as strong acids, strong bases or high temperatures, the molecular structure may change, triggering chemical reactions. In practical applications, special attention should be paid to properly control the reaction conditions to ensure the stability of the properties of the compound.
    Is 2-Chloro-3-pyrrol-1-ylpyridine chemically stable?
    2-Chloro-3-pyrrole-1-ylpyridine, this is an organic compound. The stability of its chemical properties depends on the environment and the reaction involved.
    Under normal and general conditions, 2-chloro-3-pyrrole-1-ylpyridine may have certain stability. However, organic compounds often exhibit various chemical activities due to specific functional groups in the structure. In this compound, the chlorine atom is connected to pyrrolyl and pyridine rings. Chlorine atoms are quite electronegative, or make the carbon atoms connected to them partially positive, which is easy to attract nucleophilic reagents to attack and initiate nucleophilic substitution reactions, which may affect their stability.
    Both pyrrole rings and pyridine rings are rich in electrons and have aromatic properties, and can participate in various electrophilic substitution reactions. In case of strong oxidizing agents or specific reaction conditions, pyrrole rings and pyridine rings may be oxidized, resulting in structural changes and impaired stability.
    In addition, external conditions such as temperature, light, pH, etc. also have significant effects on the stability of 2-chloro-3-pyrrole-1-ylpyridine. High temperature or light may cause its chemical bonds to break, initiating decomposition reactions. In a strong acid or base environment, the compound may undergo hydrolysis, isomerization and other reactions catalyzed by acid and base, and the stability is reduced.
    In summary, the stability of 2-chloro-3-pyrrole-1-ylpyridine is not invariable, depending on the specific environment and reaction conditions, and may exhibit different chemical stability under different circumstances.
    What are 2-Chloro-3-pyrrol-1-ylpyridine synthesis methods?
    The synthesis method of 2-chloro-3-pyrrole-1-ylpyridine is of interest in the field of organic synthetic chemistry. There are several ways to synthesize it.
    First, chlorine atoms can be introduced into the specific position of the pyridine ring by halogenation reaction through pyridine derivatives as starting materials, and then pyrrole-1-yl can be introduced through nucleophilic substitution reaction. In this process, the halogenation step requires careful selection of halogenation reagents and reaction conditions. If a suitable halogenating agent is used, at the appropriate temperature and solvent environment, the halogenation reaction can selectively occur at the 2-position of the pyridine ring, which lays the foundation for subsequent nucleophilic substitution. When nucleophilic substitution occurs, pyrrole anions or their equivalent reagents react with chloropyridine-containing derivatives to achieve the synthesis of the target product.
    Second, pyrrole derivatives can also be used to properly protect pyrrole first, and then react with pyridine halides. By reasonably regulating the reaction conditions, the coupling reaction between the two can occur. In this path, the choice of pyrrole protecting groups is very critical, which not only needs to ensure stability in subsequent reactions, but also can be gently removed after the reaction. Factors such as catalysts, bases and solvents for the coupling reaction also have a significant impact on the reaction yield and selectivity.
    Furthermore, a multi-step tandem reaction strategy can also be used. First, pyridine and pyrrole are functionalized separately, and then in the same reaction system, with the help of a series of continuous reactions, the structure of 2-chloro-3-pyrrole-1-ylpyridine is constructed in one step. Although this method is compact in steps, it requires extremely high precision control of reaction conditions. Only by having a deep understanding of the activity and selectivity of each step of the reaction can the tandem reaction proceed smoothly and obtain the target product.
    What is the price range of 2-Chloro-3-pyrrol-1-ylpyridine in the market?
    The price range of 2-chloro-3-pyrrole-1-ylpyridine is difficult to determine between cities. The price of this chemical often varies due to many factors. First, the source of production is also different. If it comes from different producers near and far, the freight will be different, and the price will also change accordingly. If the origin is close, the freight will be saved, and the price may be slightly cheaper; if it is far away, the fee will be high and the price will be high.
    The amount of dosage will be used. If the buyer's demand is huge, the manufacturer may give it a preferential price due to small profits but quick turnover, and the buyer in bulk can get a cheaper value; and if you only buy a small amount, the price will often be higher.
    Furthermore, the supply and demand situation of the market is also the key. When the demand exceeds the supply, the product is in short supply, and the price will rise; if the supply exceeds the demand, the market will be flooded, and the manufacturer will sell its goods or reduce the price to promote it.
    In addition, the quality of the product also affects the price. Those with high quality will have higher prices if they spend more effort or materials at the time of preparation; those with lower quality will have lower prices. < Br >
    Therefore, in order to know the exact price of 2-chloro-3-pyrrole-1-ylpyridine, it is necessary to carefully consider various factors and consult various suppliers to obtain a near-real price. However, at present, it is difficult to determine its exact price range.