2 Chloro 3 Ol 6 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-3-ol-6-(trifluoromethyl)pyridine

    Specifications

    HS Code

    484869

    Chemical Formula C6H3ClF3NO
    Molecular Weight 197.54
    Appearance Solid (usually)
    Solubility In Water Low (organic compound, relatively hydrophobic)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Vapor Pressure Low (as a solid or high - boiling liquid)
    Stability Stable under normal conditions, but reactive to strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2-Chloro-3-ol-6-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-Chloro-3-ol-6- (trifluoromethyl) pyridine?
    2-Chloro-3-alcohol-6- (trifluoromethyl) pyridine, this is an organic compound. It has a wide range of uses in the field of medicine and is often used as a key intermediate in drug synthesis. For example, it can be used to prepare drug molecules with specific biological activities. By modifying and reacting with its structure, active ingredients for treating specific diseases can be obtained. The chlorine atom, hydroxyl group and trifluoromethyl group contained in this compound give it unique chemical properties and reactivity, and can participate in a variety of organic reactions, laying the foundation for the construction of complex drug structures.
    In the field of pesticides, it also plays an important role. It can be used as a raw material for the synthesis of new pesticides. Due to the introduction of trifluoromethyl, the biological activity, stability and environmental adaptability of pesticides can often be improved. The synthesized pesticides may have high insecticidal, bactericidal or herbicidal properties, providing powerful means for pest control and weed control in agricultural production.
    Furthermore, in the field of materials science, 2-chloro-3-alcohol-6 - (trifluoromethyl) pyridine is also useful. It can be used as a starting material for the synthesis of functional materials, and it can be introduced into the polymer material structure through chemical reactions to improve the properties of the materials, such as improving the chemical resistance, thermal stability or optical properties of the materials, so as to meet the needs of special materials in different fields.
    In conclusion, 2-chloro-3-alcohol-6-trifluoromethyl) pyridine is an important basic raw material in many fields such as medicine, pesticides, and materials science due to its unique structure and reactivity. It is of great significance to promote the development of various fields.
    What are the physical properties of 2-Chloro-3-ol-6- (trifluoromethyl) pyridine
    2-Chloro-3-alcohol-6- (trifluoromethyl) pyridine is one of the organic compounds. Its physical properties are quite important to the world.
    First of all, its appearance, under normal conditions, is either a colorless to light yellow liquid, or a crystalline solid, which varies depending on environmental conditions. Looking at its color and shape can be one of the aids in identifying this substance.
    Furthermore, when it comes to its melting point, the melting point of this substance has a certain numerical range due to the characteristics of the molecular structure. However, in order to determine the exact melting point, it needs to be determined by rigorous experiments. The melting point depends on the strength of the intermolecular forces. The structure of this compound makes the intermolecular forces unique, so the melting point has its own specificity.
    The boiling point is also an important physical property. When appropriate temperature and pressure conditions are applied, the substance will reach the boiling point and undergo a phase change, from liquid to gaseous. The value of the boiling point reflects the energy required for the molecules to break free from each other, from which the degree of intermolecular interaction can be seen.
    In terms of solubility, 2-chloro-3-alcohol-6 - (trifluoromethyl) pyridine in organic solvents may exhibit different solubility properties. In some polar organic solvents, such as alcohols and ketones, it may have good solubility. Because the polarity of the molecule matches the polarity of the organic solvent, it follows the principle of "similar dissolution". In non-polar solvents, such as alkanes, its solubility may be poor.
    The density is the mass of the substance per unit volume. The value of its density is determined by the mass of the molecule and the way of packing. Accurate determination of its density is of great significance in many fields such as chemical production and quality control.
    In addition, the volatility of this substance is also one of the physical properties. Volatility is related to the difficulty of changing from liquid to gas at room temperature and pressure. Due to the presence of chlorine atoms, trifluoromethyl and other groups in its molecular structure, it may have a significant impact on its volatility.
    In summary, the physical properties of 2-chloro-3-alcohol-6 - (trifluoromethyl) pyridine, such as appearance, melting point, boiling point, solubility, density, and volatility, are interrelated and have their own uses. They are all indispensable factors for chemical research, industrial production, and many other aspects.
    What are the synthesis methods of 2-Chloro-3-ol-6- (trifluoromethyl) pyridine
    The method of preparing 2-chloro-3-alcohol-6- (trifluoromethyl) pyridine has been explored by many scholars in the past, and several common methods are described below.
    First, the pyridine derivative containing a specific substituent is used as the starting material, and it is prepared by a series of reactions such as halogenation and hydroxylation. First, chlorine atoms are introduced at a specific position on the pyridine ring. This halogenation step requires careful selection of halogenation reagents and reaction conditions. If a halogenating agent is reacted with a suitable solvent and temperature, chloropyridine intermediates can be obtained. Then, in another reaction stage, through the hydroxylation reaction, the hydroxyl group is introduced at a suitable position. This step also requires attention to the activity of the reagent and the reaction environment to prevent side reactions from occurring, so that the target product can be obtained.
    Second, the strategy of metal catalysis is adopted. A specific metal catalyst is used to guide the reactants to precisely carry out substitution reactions on the pyridine ring with the help of its unique catalytic activity. For example, using a metal complex as a catalyst, with the assistance of ligands, the reactants can achieve the substitution of chlorine atoms and hydroxyl groups at designated positions on the pyridine ring under mild reaction conditions. This process requires high activity, selectivity and stability of the catalyst, and requires fine regulation of reaction parameters.
    Third, starting from the pyridine precursor containing trifluoromethyl, it is achieved by gradually modifying the substituents on the pyridine ring. The pyridine skeleton containing trifluoromethyl is first constructed, and then chlorine atoms and hydroxyl groups are introduced in sequence. In this process, the control of the order and conditions of each step of the reaction is very important. It is necessary to weigh the mutual effects of each reaction step to avoid adverse effects on the introduced substituents. After careful regulation of the multi-step reaction, 2-chloro-3-ol-6- (trifluoromethyl) pyridine is finally obtained.
    What are the precautions for 2-Chloro-3-ol-6- (trifluoromethyl) pyridine in storage and transportation?
    2-Chloro-3-hydroxy-6- (trifluoromethyl) pyridine This product requires careful attention during storage and transportation.
    The first storage environment must be dry and cool. Because of its active chemical properties, it is easy to deteriorate when wet. If the ambient humidity is high, the moisture may chemically react with the pyridine, which will damage its quality. And high temperature is also a big taboo. High temperature will increase its molecular activity or cause adverse reactions such as decomposition, so it needs to be placed in a low temperature to prevent accidents.
    Second word packaging material, choose the appropriate one. This pyridine is corrosive to a certain extent, and ordinary materials may be difficult to resist. It is advisable to use corrosion-resistant containers, such as special glass or specific plastic materials, to ensure that the packaging is tight and prevent the risk of leakage. If there is an omission in the packaging, not only will the material be damaged, but it may also endanger the safety of the surrounding environment and personnel.
    When transporting, it is necessary to drive at a steady speed. Violent actions such as sudden braking and sharp turns may cause the container to collide and damage, causing leakage. And the environment in the transportation vehicle should also be similar to the storage environment, maintaining a dry and low temperature. Furthermore, strict monitoring is required during transportation. If abnormal temperature, humidity, or packaging is malfunctioning, it must be disposed of immediately.
    In addition, relevant operators also need professional training to be familiar with the characteristics of this substance and emergency treatment methods. In the event of an accident such as a leak, they can respond quickly and correctly to minimize the harm. In short, the storage and transportation of 2-chloro-3-hydroxy-6- (trifluoromethyl) pyridine, all details are related to success or failure and safety, and no care should be taken.
    What are the safety risks associated with 2-Chloro-3-ol-6- (trifluoromethyl) pyridine?
    2-Chloro-3-hydroxy-6- (trifluoromethyl) pyridine This substance is related to many safety risks.
    It is chemically active and can damage the skin and eyes during operation or due to contact. The cover is highly irritating to the skin mucosa because it contains chlorine, fluorine and other elements. If it accidentally touches the skin, rinse it with plenty of water as soon as possible. If it enters the eyes, it needs to be rinsed immediately and seek medical attention.
    And because it is an organic compound, it may be flammable under certain conditions. In case of open flames or hot topics, there is a risk of burning, and even explosion. Therefore, the storage place must be kept away from fire and heat sources, and well ventilated.
    In addition, its volatile vapors may cause inhalation hazards. If inhaled, or affect the respiratory system, causing cough, asthma and other diseases. When operating, prepare ventilation equipment or wear a gas mask to protect respiratory safety.
    In addition, this compound is difficult to degrade in the environment and accumulates in contaminated soil and water bodies. When disposing, it must be properly handled in accordance with relevant laws and regulations, and cannot be dumped at will, so as not to cause harm to the environment. Those who operate and come into contact with this substance need to know the safety risks in detail, abide by the operating procedures, and take protective measures to ensure that security is safe.