2-CHLORO-3-NITRO-6-METHOXYPYRIDINE

2-Chloro-3-nitro-6-methoxypyridine has a wide range of uses. In the field of medicine, this compound is often a key intermediate for the synthesis of many specific drugs. The special structure of the geinpyridine ring gives it unique chemical activity and spatial structure after introducing chlorine, nitro and methoxy groups, making it easy to construct complex molecular structures with specific pharmacological activities. For example, in the development of antibacterial drugs, it can be combined with other active groups to create new drugs with high inhibitory effect against specific bacteria.
In the field of pesticides, 2-chloro-3-nitro-6-methoxypyridine also plays an important role. It can be used as a starting material for the synthesis of new pesticides, and chemically modified and reacted to produce pesticide products with high insecticidal, bactericidal or herbicidal properties. Due to its structural characteristics, it can accurately act on specific physiological targets of pests, improve pesticide selectivity and effect, and reduce adverse effects on the environment and non-target organisms.
In addition, in the field of materials science, this compound may participate in the synthesis of functional materials. With its unique chemical properties, it may endow materials with special properties such as photoelectric properties and stability, and be applied to the research and development of organic Light Emitting Diodes, sensors and other materials, providing novel chemical components and ideas for the creation of new materials.
Overall, 2-chloro-3-nitro-6-methoxypyridine has important application value in many fields such as medicine, pesticides and materials science, providing a key chemical basis and possibility for innovation and development in various fields.

2-Chloro-3-nitro-6-methoxypyridine is a kind of organic compound. Its physical properties are quite important and need to be carefully considered in the research and application of chemical and related fields.
Looking at its properties, it is mostly solid under normal conditions, due to the force between molecules. However, the specific appearance may vary depending on the purity and preparation conditions, or it is a white to light yellow crystalline powder with a fine texture.
When it comes to the melting point, the melting point of this compound is specific, about [X] ° C. The determination of the melting point is of great significance in identifying its purity and judging whether it is mixed with impurities. If the purity is high, the melting point is more sensitive and the fluctuation range is very small; if it contains impurities, the melting point may decrease and the melting range becomes wider.
In terms of boiling point, it also has a specific value, which is about [X] ° C. The level of boiling point is closely related to the intermolecular force. In its molecular structure, the presence of chlorine atoms, nitro groups and methoxy groups affects the intermolecular force, which in turn determines the boiling point. Knowledge of boiling point is indispensable in the separation and purification of this compound.
In terms of solubility, 2-chloro-3-nitro-6-methoxy pyridine has different solubility in organic solvents. In common organic solvents, it has good solubility in some polar organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF). Because the molecular structure has a certain polarity, it can form intermolecular forces with polar solvents, such as hydrogen bonds, van der Waals forces, etc., to help it dissolve. However, the solubility in water is poor, because the polarity of the water molecule is different from the polarity of the compound, and the intermolecular force is difficult to effectively match the water molecule, so it is difficult to dissolve.
In addition, the density of the compound is about [X] g/cm ³, which is a physical property that is crucial in terms of metrology, reaction system formulation, etc. Only by knowing the density can a certain quality of compounds be accurately measured and applied to experiments or production.
In summary, the physical properties of 2-chloro-3-nitro-6-methoxypyridine, such as properties, melting point, boiling point, solubility, density, etc., are key parameters in the process of research, production and application, and are of great significance for controlling its performance and behavior.

To prepare 2-chloro-3-nitro-6-methoxypyridine, you can follow the following method.
Take 6-methoxypyridine as the starting material first, because the pyridine ring has a certain reactivity. The first step is to react with a suitable chlorination reagent, such as thionyl chloride or phosphorus oxychloride, under suitable conditions. Usually within a certain temperature range or with the help of a catalyst, the specific position of the pyridine ring is chlorinated to obtain 2-chloro-6-methoxypyridine. In this step, the amount of chlorination reagent, reaction temperature and time are all key factors. If the temperature is too high, the by-product of polychlorination is feared; if the temperature is too low, the reaction rate is slow.
After 2-chloro-6-methoxypyridine is obtained, the nitrification reaction is continued. The mixed acid composed of concentrated nitric acid and concentrated sulfuric acid is used as the nitrifying agent, and this mixed acid can produce active nitrifying species. During the reaction, 2-chloro-6-methoxypyridine is slowly added to the mixed acid, while the temperature is strictly controlled. Because the nitrification reaction is strongly exothermic, if the temperature is out of control, it is easy to cause a cluster of side reactions, such as excessive nitrification or the destruction of pyridine rings. In this process, according to the characteristics of the substrate, the mixing ratio of acid, the dripping speed and the reaction temperature are precisely controlled, so that the nitro group is selectively introduced into the 3-position of the pyridine ring, and the final target product is 2-chloro-3-nitro-6-methoxypyridine.
After each step of the reaction, it needs to be separated and purified, such as extraction, distillation, recrystallization, etc., to remove impurities and improve the purity of the product. And the reaction conditions of each step need to be carefully explored and optimized to obtain the product with ideal yield and purity.

Looking at this question, I am inquiring about the market price range of 2-chloro-3-nitro-6-methoxypyridine. Sadly, the market price often changes from time to time, and is also affected by factors such as supply and demand, quality, and origin.
I have heard that in the past, the price of such chemical products may fluctuate due to the abundance of raw materials. If the supply of raw materials is abundant, the price may become stable and cheap; if the raw materials are scarce, the price will rise.
In the chemical market, the price varies from place to place. In prosperous and well-connected places, the logistics is convenient, and the price may be slightly flat; in remote places, the transportation is difficult, and the price may be slightly higher.
Also, product quality is also related to price. Those with high purity and few impurities must have a higher price than regular products. As for the exact price range, it is difficult to determine. The market is unpredictable. If you want to know the exact number, you should go to the chemical market in person, consult merchants, or refer to professional chemical information platforms to get the details.

2-Chloro-3-nitro-6-methoxypyridine is a key fine chemical in the field of organic synthesis and is widely used in medicine, pesticide and other industries. However, although there is no detailed and complete ancient literature on its exact manufacturer, many modern chemical companies are involved in the production of this product today.
In the land of China, the Yangtze River Delta and the Pearl River Delta, the chemical industry is prosperous and prosperous, and many companies focus on the production of fine chemicals, including the manufacture of 2-chloro-3-nitro-6-methoxypyridine. This region has a complete chemical industry chain, complete supporting facilities, and strong technical force, providing convenient conditions for the production of such fine chemicals.
There are also strong chemical companies overseas. With a long history of chemical production and advanced technology, they may be engaged in the production of 2-chloro-3-nitro-6-methoxypyridine. Chemical companies in some developed countries in Europe and the United States have huge investment in technology research and development, exquisite production technology, and occupy an important position in the high-end fine chemical market.
However, to know the exact manufacturer, you need to use the chemical industry information platform, professional chemical exhibition materials, or directly contact chemical product distributors and suppliers. They may be able to provide the latest and accurate manufacturer information. The dynamic changes of the chemical industry, the rise and fall of manufacturers, and the adjustment of production products occur from time to time, so the information needs to be timely updated and verified to ensure accuracy.