2 Chloro 3 Cyano Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-3-Cyano Pyridine

    Specifications

    HS Code

    303616

    Chemical Formula C6H3ClN2
    Molecular Weight 138.55
    Appearance white to off - white solid
    Melting Point 61 - 64 °C
    Boiling Point 257 - 258 °C
    Density 1.32 g/cm³
    Solubility In Water insoluble
    Solubility In Organic Solvents soluble in many organic solvents like ethanol, acetone
    Flash Point 110 °C
    Pka ~1.5

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    General Information
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    Frequently Asked Questions

    As a leading 2-Chloro-3-Cyano Pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-chloro-3-cyanopyridine?
    2-% -3-deuteryl pyridine is mainly used in "Tiangong", and is mostly used in the chemical industry.
    In the chemical industry, its important components are in the synthesis. For example, in the synthesis of some high-performance engineering plastics, 2-% -3-deuteryl pyridine is a specific polymerization step. With its special molecule, it can improve the arrangement of the whole polymer, so that engineering plastics have better mechanical properties and resistance. In the new rubber, it can also be used as a raw material for vulcanization promotion, accelerating the vulcanization reaction rate, improving the physical properties of rubber, and enhancing the durability of rubber products.
    In terms of
    , this compound is often used in the synthesis of rubber. In the development of many biologically active chemical molecules, 2-%-3-deuterylpyridine can be filled with the parent nucleus or active group of the chemical industry. Like some antibacterial compounds, with its starting materials, multi-step repair, it can obtain compounds with inhibitory effects on specific pathogens. In addition, in the research of the treatment of certain spiritual diseases, it has established a molecular framework with specific biological activities, which helps the chemical to better act on the receptors, and improve the treatment effect.
    , 2-%-3-deuterylpyridine has its specialization properties, which plays an important role in the chemical synthesis of polymers and the development of new chemical compounds, and promotes the development of the phase.
    What are the physical properties of 2-chloro-3-cyanopyridine?
    The physical properties of 2-% -3-deuteryl phenyl groups are similar in density, melting, boiling, solubility, and stability.
    Its density is different from that of ordinary homologues. Due to the large atomic weight of deuterium atoms, the density of 2-3-deuteryl phenyl containing deuterium is slightly higher. This is due to the difference in atomic weight, and the molecular force is also affected by its influence, which affects the left and right densities.
    In terms of melting, due to the similar deuterium properties, the heavy deuterium content makes the molecule vibrate and the lattice can be changed. Therefore, the molten phase of 2-3-deuterylphenyl group may be increased, and more energy is required to break the lattice and make it solid and liquid.
    As for boiling, the principle is similar to melting. Due to the increase in molecular weight and the increase in molecular force, in order to make the liquid melt, more energy is required to overcome the attractive force of the molecule, so boiling may also increase.
    In terms of solubility, 2-3-deuterylphenyl group still follows a similar principle of miscibility. It is phenyl, has a certain hydrophobicity, and has good solubility in non-soluble or weakly soluble solutions, such as benzene and toluene; while in soluble solutions, such as water, the solubility is poor.
    In terms of properties, the properties of 2-3-deuterylphenyl are determined by the whole molecule. Phenyl and non-soluble groups have slightly poor properties of deuterium and deuterium, but the properties of the whole molecule are limited, so it still exhibits weak properties or approximate non-soluble properties. This property determines its performance in polymorphism and physical processes, such as in color separation, extraction and other operations, which are influenced by factors.
    What are the chemical synthesis methods of 2-chloro-3-cyanopyridine?
    To prepare 2-cyano-3-cyanopyridine, there are various methods.
    First, it can be prepared by cyanidation of pyridine compounds. Choose suitable pyridine derivatives and react with cyanide reagents under specific reaction conditions. Such as metal cyanides, such as potassium cyanide, sodium cyanide, etc., in organic solvents, under the action of catalysts, a cyanyl group is introduced into a specific position on the pyridine ring. This process requires fine regulation of reaction temperature, time and reagent dosage. If the temperature is too high or the time is too long, it may cause side reactions such as multiple substitutions, which will affect the purity and yield of the product.
    Second, it can be converted and synthesized by nitrogen-containing heterocyclic compounds. The heterocyclic ring with similar structure is prepared first, and then the cyanyl group is introduced through the conversion of functional groups. For example, taking a nitrogen-containing heterocyclic ring as the starting material, it is first modified to make a specific position active, and then the cyanyl group is introduced by suitable cyanidation means. This approach requires a deep understanding of the chemical properties of the heterocyclic ring, precise design of the reaction route, and ensure that the reaction proceeds in the expected direction.
    Third, the organic synthesis strategy can be used to construct the target structure through a multi-step reaction. First, a simple organic compound is used as the starting material, and the pyridine skeleton is constructed through reactions such as condensation and cyclization, and then the cyanyl group is introduced. Although this method has complicated steps, it can flexibly regulate the structure and improve the selectivity of the product. Every step of the reaction needs to be strictly controlled, from the selection of raw materials, the optimization of reaction conditions to the separation and purification of intermediates, all of which are related to the quality of the final product.
    There are various methods for preparing 2-cyano-3-cyanopyridine, each with advantages and disadvantages. According to actual needs, such as raw material availability, cost, product purity requirements, etc., carefully select and fine optimize the reaction conditions to obtain satisfactory results.
    What are the precautions for storing and transporting 2-chloro-3-cyanopyridine?
    In the process of storage and storage of 2-% 3-aminopyridine, the following things are important:
    First, because it has a certain chemical activity, it must be dry and well preserved. In the tidal environment, it is easy to cause the biochemical reaction of water vapor, and cause the material to be damaged. If it is stored in the tidal environment, it may be changed in time, and the efficiency is also greatly reduced.
    Second, it is necessary to reduce the source of ignition and the source of ignition. 2-% 3-aminopyridine is flammable. In case of open flames, high temperatures, it may be dangerous to burn or even explode. In the chemical industry, if the source of ignition is not controlled in the storage area of this substance, once it burns, the consequences will be unimaginable.
    Third, it needs to be properly packaged in the first place. The packaging material should have good sealing and anti-collision properties to prevent leakage due to package damage on the way. If the road is bumpy and the package is not good, it may leak, and the environment and human safety will become a threat.
    Fourth, do not mix and mix oxidize, acids and other substances. 2-% -3-aminopyridine is oxidized and connected, which is easy to cause oxidation reaction. When the acid meets, or the neutralization reaction is strong, it may put a large amount of energy and lead to safety accidents. If the acid is placed in the middle of the package, or the same two, a little carelessness will cause a big problem.
    Fifth, the operator should take good preventive measures, such as wearing anti-wear gloves, safety eyes, gas masks, etc. Because of the irritation caused by the skin, eyes, respiratory tract, etc. If the operation is not protected, it is easy to harm the body.
    What is the market price range for 2-chloro-3-cyanopyridine?
    Today there are 2-alkyl-3-alkylpyridine, and its market price range is based on the method of "Tiangong Kaiwu".
    The price of various items in the city often varies depending on the origin, season, and quality. For 2-alkyl-3-alkylpyridine, if the production is abundant, the place is close to the market, and the quality is high, the price may be slightly flat. However, if the origin is remote, the collection is difficult, or the quality is flawed, the price will increase.
    As far as common sense is concerned, the choice of raw materials and the preparation process are all related to the price. If the raw materials are easy to obtain and the preparation method is simple, the cost can be reduced, and the price will also drop. On the contrary, the raw materials are rare, the preparation is cumbersome, and the price must be high.
    And the supply and demand of the market are also the key to the price. If the demand for this product in the market is quite strong, but the supply is limited, the merchant will raise its price; if the demand is weak and the supply is sufficient, the price will automatically decline.
    Taking all factors into account, the market price of 2-alkane-3-alkylpyridine is roughly between [X] and [X]. However, this is only an approximate number, and the actual price depends on the specific situation at that time. It may change from time to time, or it may vary from city to city, and cannot be generalized.