2 Chloro 3 Cyano 6 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-3-cyano-6-methylpyridine

    Specifications

    HS Code

    388430

    Chemical Formula C7H5ClN2
    Molar Mass 152.58 g/mol
    Appearance Solid (usually)
    Color May be white to off - white
    Solubility In Water Low solubility (due to non - polar nature of the pyridine ring and hydrophobic groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Odor May have a characteristic pyridine - like odor (usually pungent)

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    General Information
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    Frequently Asked Questions

    As a leading 2-Chloro-3-cyano-6-methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Chloro-3-cyano-6-methylpyridine?
    2-Chloro-3-cyano-6-methylpyridine is also an organic compound. It is widely used in the field of pesticides and is often used as a key intermediate for the creation of new insecticides and fungicides. Due to its special chemical structure, the compound can interact with specific biomacromolecules in pests and pathogens, interfering with their normal physiological metabolism, and achieving the purpose of controlling pests and diseases.
    In the field of medicinal chemistry, 2-chloro-3-cyano-6-methylpyridine is also an important synthetic building block. Pharmaceutical researchers can synthesize many potentially bioactive compounds by modifying and modifying their structures, which can be used to develop drugs for the treatment of various diseases, such as anti-tumor, anti-viral and other drugs.
    Furthermore, in the field of materials science, it can participate in the synthesis of some functional materials. After specific chemical reactions, it is introduced into the structure of polymer materials, giving the materials unique properties such as special optical and electrical properties, thus expanding the application range of materials and showing potential application value in photoelectric materials.
    In general, 2-chloro-3-cyano-6-methylpyridine plays an important role in many fields such as pesticides, medicine, materials, etc., providing a key material basis for technological innovation and new Product Research & Development in related fields.
    What are 2-Chloro-3-cyano-6-methylpyridine synthesis methods?
    The synthesis of 2-chloro-3-cyano-6-methylpyridine has attracted much attention in the field of organic synthesis. In the past, many wise men contained relevant synthesis methods in the classics, and the following are common ones.
    First, 2-methyl-3-cyanopyridine is used as the starting material. This raw material and a suitable chlorination reagent, such as sulfonyl chloride, can be obtained under suitable reaction conditions. The reaction needs to be carried out in an organic solvent, such as dichloromethane or chloroform, and a catalyst, such as pyridine or triethylamine, is required to promote the smooth occurrence of the reaction. The reaction temperature is also crucial, usually between low temperature and room temperature, such as 0 ° C to 25 ° C, so that the reaction can be carried out effectively and side reactions can be avoided.
    Second, 6-methyl-3-pyridinecarboxylic acid can also be used as the starting material. It is first converted into the corresponding amide, which can be achieved by reacting with ammonia or amines. Then it is dehydrated to form a cyanyl group. This step is often treated with dehydrating agents such as phosphorus pentoxide or phosphorus oxychloride. Finally, chlorine atoms are introduced at the 2-position of the pyridine ring, which can be completed using chlorination reagents such as dichlorosulfoxide or phosphorus trichloride under appropriate reaction conditions. This route is a bit complicated, but the raw materials are easy to obtain, and the reaction conditions of each step are relatively mild, which is also an effective way for synthesis.
    Third, 2-chloro-6-methylpyridine is used as the starting material. First, it is cyanylated. This reaction can use metal cyanides, such as cuprous cyanide or potassium cyanide, under appropriate ligands and reaction conditions to introduce cyanyl groups into the 3-position of pyridine. This reaction often needs to be carried out in an organic solvent under heating and inert gas protection to ensure the efficient and safe reaction.
    The above methods for synthesizing 2-chloro-3-cyano-6-methylpyridine have their own advantages and disadvantages. The appropriate synthesis path should be carefully selected according to the actual situation, such as the availability of raw materials, reaction cost, yield and purity requirements.
    What are the physical properties of 2-Chloro-3-cyano-6-methylpyridine?
    2-Chloro-3-cyano-6-methylpyridine is an important compound in the field of organic chemistry. Its physical properties are unique. At room temperature, it is mostly in a solid state and has high stability.
    Looking at its melting point, the melting point of this compound is in a specific range, which is of great significance for the identification and purification of this substance. By measuring the melting point, the purity can be determined. If the purity is high, the melting point value should be very close to the theoretical value; if there are impurities, the melting point will change, or decrease, or the melting range will become wider.
    In addition to its solubility, 2-chloro-3-cyano-6-methylpyridine exhibits different degrees of solubility in various organic solvents. In common organic solvents, such as ethanol, acetone, etc., it can exhibit moderate solubility. This solubility property provides convenience for the selection of reaction media in the process of organic synthesis. According to the reaction requirements, a suitable solvent can be selected to fully dissolve the reactants to promote efficient reaction.
    When it comes to density, it also has a fixed value. Density, as one of the important physical properties of substances, should not be underestimated in storage and transportation. Knowing its density is helpful for rational planning of storage container specifications, as well as weight and volume control during transportation.
    In addition, the color state of the compound is also worthy of attention. Under normal circumstances, it exhibits a specific color state, which can be used as the basis for preliminary identification. Once the color state is abnormal, it may suggest that there is a problem with its purity, or a chemical reaction occurs.
    The physical properties of 2-chloro-3-cyano-6-methyl pyridine, such as melting point, solubility, density and color state, play a key role in organic synthesis, analysis and detection, and storage and transportation. It provides an important reference for research and application in related fields.
    2-Chloro-3-cyano-6-methylpyridine What are the precautions during storage and transportation?
    2-Chloro-3-cyano-6-methylpyridine is an organic compound. When storing and transporting, you must pay attention to the following matters:
    One is the storage environment. This compound should be stored in a cool, dry and well-ventilated place. Due to high temperature or humidity, it is very likely to cause chemical reactions to occur, which in turn affects the quality. For example, if it is in a high temperature environment, it may accelerate decomposition; while a humid environment may cause it to become damp and cause deterioration. Do not place it in direct sunlight to prevent light from causing photochemical reactions.
    The second is about packaging. Be sure to use a well-sealed packaging container to prevent it from coming into contact with air, moisture, etc. It is usually packed in glass bottles, plastic bottles or special sealed metal containers. The packaging should be sturdy and durable, able to withstand a certain external impact, and prevent the leakage caused by the damage of the container during transportation.
    Third, in terms of transportation. During transportation, it should be avoided to mix with oxidizing agents, acids, alkalis and other substances. Due to its active chemical properties, severe chemical reactions can easily occur in contact with these substances, and even cause serious accidents such as explosions and fires. Transportation vehicles also need to have good ventilation equipment, and transportation personnel must be familiar with the characteristics of this compound and emergency treatment methods.
    Fourth, the label is clear. Key information such as the name, properties, and warning signs of the compound should be clearly marked on the package. In this way, both storage managers and transporters can see its characteristics at a glance, so that appropriate protective measures and operation methods can be taken.
    In short, the storage and transportation of 2-chloro-3-cyano-6-methylpyridine needs to be carefully controlled in terms of environment, packaging, mixing taboos, and labeling to ensure its safety and stability.
    What is the market price of 2-Chloro-3-cyano-6-methylpyridine?
    Fu 2-chloro-3-cyano-6-methylpyridine is a fine chemical among chemical products. Its market price often varies for many reasons, making it difficult to generalize.
    One is related to the preparation method. If it is obtained by a simple and low-cost method, its price may be slightly flat; if the preparation is difficult, requires a variety of rare reagents, and requires a lot of energy consumption, the price will be high. If a new and efficient synthesis method can reduce the consumption of its preparation, its market price may be lower than that obtained by the previous production method.
    Second, depending on the supply and demand of the market. If many industries, such as pharmaceuticals and pesticides, are in high demand for 2-chloro-3-cyano-6-methylpyridine, but there are few producers, and the demand exceeds the supply, the price will rise; on the contrary, if the supply exceeds the demand, the factories are full of inventory, and the demand is few, the price will drop.
    Third, the price of raw materials also has a great impact. If the price of raw materials required for the preparation of this product changes due to the origin, season, policy, etc., the price of 2-chloro-3-cyano-6-methylpyridine will also change. For example, if one of the raw materials is reduced due to disasters at the place of origin, the price will rise several times, and the price of this product will also rise.
    Fourth, the price varies from region to region. In places where the chemical industry gathers, due to the large number of producers, the competition is intense, and the transportation is convenient, the price may be slightly lower; in remote places, the transportation cost is greatly increased, and there is no competition among multiple plants, the price may be higher.
    Therefore, in order to know the exact market price of 2-chloro-3-cyano-6-methylpyridine, it is necessary to observe the market situation in real time and consult all suppliers to obtain a more accurate number.