2 Chloro 3 Bromo Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Chloro-3-Bromo Pyridine

    Specifications

    HS Code

    389942

    Chemical Formula C5H3BrClN
    Molecular Weight 192.44
    Appearance Typically a solid (physical state can vary based on conditions)
    Boiling Point Approximately 209 - 210 °C
    Melting Point Around 40 - 42 °C
    Density No precise standard value, but density of related pyridine derivatives is around 1.7 - 1.9 g/cm³
    Solubility Soluble in many organic solvents like dichloromethane, chloroform, less soluble in water
    Odor Characteristic pungent pyridine - like odor
    Flash Point No widely - reported exact value, but for similar halogenated pyridines, it's around 80 - 90 °C
    Stability Stable under normal conditions, but can react with strong oxidizing agents

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    General Information
    Where to Buy 2-Chloro-3-Bromo Pyridine in China?
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    Frequently Asked Questions

    As a leading 2-Chloro-3-Bromo Pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-chloro-3-bromopyridine?
    The physical rationality of 2-% -3-helium is as follows:











    3-helium




    3-helium




    3-helium




    < 3-Helium contains two neutrons and one neutron, which is similar to that of 4-helium. 3-helium has some special physical properties. At low temperatures, 3-helium can be superfluidized, and its viscosity is close to zero. It can flow with resistance and can climb up the container wall to overflow. Its efficiency is also high in superfluidic conditions, which is very different from that of ordinary materials. In addition, 3-helium has a smaller density than air, so it is often used in specific mixtures to adjust its density characteristics. In the field of low-level physics research, 3-helium has become an important research image due to its special properties. It plays an indispensable role in exploring physical phenomena such as quantum physics at low temperatures.
    What are the chemical properties of 2-chloro-3-bromopyridine?
    2-% -3-helium, with its chemical properties, has many special properties. It is often found in nature and mostly exists in the form of hydrogen (H ²). Its density, the least dense of the elements, is often used as a fuel, because it burns raw water and is dyed, such as in the energy pool, which is powerful in the energy field. And atoms are prone to lose their only atoms, which are H-atoms, and play an important role in acid reactions.
    As far as 3-helium, the isotope of helium is ³ He, and its nucleus contains two atoms and one neutron. The properties of helium are determined, and the atoms are often colored and tasted. The He phase is very rare in the normal environment, and the content is rare. He has a low boiling temperature, which is very important in low-temperature physics research, and can be used in the low-temperature environment required for the fabrication of super-magnetism. In addition, He also has its characteristics in nuclear fusion. In some small-scale nuclear fusion research, He is expected to be one of the raw materials for nuclear fusion, which is expected to be the way of energy solution solutions. In addition, 2-3-helium is the same element, but its chemical properties are due to the atom, and it shows important characteristics in different fields.
    What are the synthesis methods of 2-chloro-3-bromopyridine?
    There are many methods for synthesizing 2-% cyanogen-3-hydroxypyridine, and several common ones are described in detail below.
    One is the synthesis path using pyridine as the starting material. First, the pyridine is electrophilically substituted to introduce the cyanyl group at the appropriate position. This step requires careful selection of reaction conditions and reagents to ensure the precise introduction of the cyanyl group into the desired check point. Subsequently, the hydroxylation reaction is carried out for another position. For example, a combination of a specific oxidizing agent and a catalyst can be used to induce the hydroxylation of a specific carbon atom on the pyridine ring, resulting in the target product 2-% cyanogen-3-hydroxypyridine. The advantage of this method is that the starting material pyridine is widely sourced and the price is moderate. However, the reaction steps are slightly complicated, and the reaction conditions are strictly controlled. The yield of each step needs to be carefully optimized to achieve the ideal synthesis effect.
    The second is to use simple compounds containing cyanide and hydroxyl groups as raw materials to construct pyridine rings through cyclization. For example, nitrile compounds and carbonyl-containing compounds with appropriate functional groups are selected. In the presence of basic catalysts, a series of nucleophilic addition, cyclization and other reactions are used to gradually construct the pyridine ring structure, and finally 2-% cyanogen-3-hydroxypyridine is generated. The advantage of this path is that the reaction steps are relatively simple, and complex pyridine rings can be directly constructed from basic raw materials. However, the requirements for the selection and preparation of raw materials are relatively high, and the structure of the raw materials needs to be precisely designed to ensure the smooth progress of the cyclization reaction, and the reaction process may be accompanied by side reactions, which need to be properly regulated to improve the selectivity of the target product.
    The third is the synthesis strategy using transition metal catalysis. With the help of the unique catalytic activity of transition metal catalysts, the coupling reaction of cyanide-containing groups and hydroxyl substrates is promoted to realize the construction of pyridine rings. For example, the use of transition metal catalysts such as palladium and copper catalyzes the reaction of halogenated pyridine derivatives with cyanide sources and hydroxylation reagents under the synergistic action of ligands. This method has the characteristics of mild reaction conditions and high selectivity, which can effectively reduce the occurrence of side reactions. However, the cost of transition metal catalysts is high, and the separation and recovery of catalysts after reaction are also issues to be considered. In actual industrial production, the relationship between cost and benefit needs to be weighed.
    What fields is 2-chloro-3-bromopyridine used in?
    The 2-% -3-helium vector is useful in the following multiple domains:
    In the aerospace domain, it is used as an efficient energy source for cleaning, providing a large thrust for rocket launch. Its high energy density characteristics enable spacecraft to generate a small amount of fuel and gain huge energy, helping them break through the attractive force of the earth and go to the vast universe. And helium, because of its low density and low density, is often used for filling balls and ships to ensure safety.
    In the energy domain, it can be used for undesirable energy sources. It burns materials and water, pollutes, and is renewable. Through fuel technology, it can efficiently convert energy, and supply energy for steam and household appliances, promoting the cleaning of energy. Helium-3 is an ideal fuel for uncontrolled nucleation. If helium-3 fuel can be used to generate huge energy, and it is almost impossible to generate radioactive materials, it is expected to solve the global energy crisis.
    In the field of research, it has anti-oxidation, anti-inflammatory and other biological effects. Research, inhalation or water use can improve the symptoms of patients with certain diseases, such as oxidative excitation diseases, neurodegenerative diseases, etc. Helium is often used in medical equipment, such as magnetic resonance imaging (MRI). Ultra-magnetic cooling, to ensure the determination of the current, and to provide support for precision.
    In the field of scientific research, atoms, due to their, have become an important image in the study of atomic physics, quantum force and other fundamental science. Through the study of the optical properties of atoms, people have a deep understanding of the atomic properties and energy systems. Helium is very important in the study of low-temperature physics. Using the ultra-low-temperature characteristics of liquid helium, it can be used to create low-end environments close to zero degrees. It is used to study ultra-low-temperature phenomena, Bose-Einstein condensation and other strange physical phenomena, and to promote the frontier development of physics.
    What is the market price of 2-chloro-3-bromopyridine?
    The market value of 2-% -3-pyridine, according to the "Tiangong Wuwu", depends on many factors.
    This material is important, and its source is the first. If it is difficult to find the land, the raw materials are easy to use, and the cost may be reduced. As "Tiangong Wuwu" says, the location is different. If the source of pyridine is close and sufficient, and it is convenient to take it, it will be difficult or flat.
    Furthermore, the method of making it is very important. Sophisticated technology can improve the quantity and increase the product. If it is used in a complex and inefficient way, the power will be higher. On the contrary, if you get a clever method, you can get twice the result with half the effort, and you can also benefit the people.
    The use of 2-%-3-pyridine also affects the price of the grid. If 2-%-3-pyridine has a wide range of uses, it is indispensable to the production and processing of it. If you ask for it, you will find it. For example, "Tiangong For example, in the ancient times, if 2-%-3-pyridine is difficult and difficult to store, it will be low-cost.
    In the city of 2-%-3-pyridine, it is not determined by one factor, and the source, method, use, supply and demand, Tibet and other factors are intersected to jointly determine its status in the city.