2 Bromoimidazo 1 2 A Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-bromoimidazo[1,2-a]pyridine

    Specifications

    HS Code

    201041

    Name 2-bromoimidazo[1,2-a]pyridine
    Molecular Formula C7H5BrN2
    Molecular Weight 197.03
    Appearance Solid (Typical)
    Cas Number 67998-29-4
    Boiling Point Approximately 300 °C
    Melting Point 82 - 84 °C
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point Approximately 135 °C

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    Frequently Asked Questions

    As a leading 2-bromoimidazo[1,2-a]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-bromoimidazo [1,2-a] pyridine?
    2 - bromoimidazo [1,2 - a] pyridine is one of the organic compounds. It has a wide range of uses and has shown its important value in many fields.
    In the field of medicinal chemistry, this compound is often a key intermediate. Due to its unique chemical structure, it can participate in various reactions and help build complex molecular structures, thus paving the way for the development of new drugs. By ingeniously modifying its structure, chemists hope to create new drugs with high pharmacological activity and low side effects to fight various diseases, such as cancer and neurological diseases.
    In the field of materials science, 2 - bromoimidazo [1,2 - a] pyridine also has potential uses. It may be used to prepare functional materials, such as optoelectronic materials. Due to its structural properties, it may endow materials with unique optical and electrical properties, making it stand out in the fields of organic Light Emitting Diodes (OLEDs), solar cells, etc., improving the performance and efficiency of such devices.
    Furthermore, in organic synthetic chemistry, this compound is a commonly used synthetic block. Chemists can take advantage of the activity of its bromine atom to connect with other organic molecules through various coupling reactions, such as Suzuki coupling, Stille coupling, etc., to expand the complexity and diversity of molecules, and synthesize many organic compounds with special structures and properties, contributing to the development of organic synthetic chemistry.
    To sum up, 2-bromoimidazo [1,2-a] pyridine plays an important role in the fields of medicine, materials and organic synthesis, and has made significant contributions to the advancement of related science and technology.
    What are the physical properties of 2-bromoimidazo [1,2-a] pyridine
    2 - bromoimidazo [1,2 - a] pyridine is an organic compound with unique physical properties and great significance in the fields of chemical industry and medicine.
    This compound is mostly solid at room temperature, and the texture is usually crystalline. The melting point and boiling point are key indicators to measure its stability and processing characteristics. Its melting point is within a specific range, which makes it melt from solid to liquid at a specific temperature, reflecting the strength of intermolecular forces. The boiling point determines the temperature at which it turns into a gaseous state when heated to a certain extent, which is of great significance for its separation and purification.
    In terms of solubility, 2 - bromoimidazo [1,2 - a] pyridine exhibits different solubility in organic solvents. In polar organic solvents, such as ethanol and acetone, it has a certain solubility, and can be well dispersed due to the interaction of molecular structure with polar solvents. In non-polar solvents, such as n-hexane, the solubility is very small, because of its weak molecular interaction with non-polar solvents.
    Density is also an important physical property. It reflects the mass of the substance per unit volume, and plays a guiding role in calculating the dosage, ratio, and density change of the mixture system. The value of density depends on the molecular mass and the way of molecular accumulation.
    In addition, the color and taste of 2-bromoimidazo [1,2-a] pyridine are also reflected in physical properties. Its color is usually lighter, and the smell may be weak and characteristic. Although subjective, these properties help to identify and judge its purity.
    These physical properties are interrelated and jointly determine the behavior of 2-bromoimidazo [1,2-a] pyridine in different scenarios, laying the foundation for its application and research.
    What are the synthesis methods of 2-bromoimidazo [1,2-a] pyridine
    2-Bromoimidazo [1,2-a] pyridine is an important organic compound, and its synthesis methods are diverse. Under the paradigm of "Tiangong Kaizi", it can be described as follows:
    First, the method of using pyridine derivatives as starting materials. First, a suitable pyridine derivative is taken, and the imidazole ring structure is introduced under specific reaction conditions. This process requires fine control of the reaction temperature, time and reagent ratio. If in a specific solvent, a base is used as the catalyst, the pyridine derivative undergoes condensation reaction with the imidazole-containing ring precursor substance. If the temperature is too high, the side reactions will increase, and if it is too low, the reaction rate will be too slow, so precise adjustment is required, which is the key.
    Second, the way to start from halogenated pyridine. Halopyridine reacts with nitrogen-containing heterocyclic compounds under the action of metal catalysts. Metal catalysts such as palladium and copper can effectively promote the formation of carbon-nitrogen bonds. In the reaction system, ligand selection is also very important, which can affect the activity and selectivity of the catalyst. If the appropriate ligand can make the reaction more efficient and selective to generate the target product 2-bromoimidazo [1,2-a] pyridine.
    Third, the method of direct reaction of imidazole with halopyridine derivatives. This reaction also needs to be carried out under appropriate conditions, such as the selection of suitable bases and solvent systems. The alkalinity of different bases affects the reaction process. Strong basic bases can accelerate the reaction, but may cause problems such as substrate decomposition, which needs to be weighed. < Br >
    When synthesizing 2-bromoimidazo [1,2-a] pyridine, regardless of the method, the reaction process needs to be closely monitored to ensure that each step of the reaction proceeds as expected in order to obtain a high purity target product.
    2-Bromoimidazo [1,2-a] pyridine is used in what fields
    2-Bromoimidazo [1,2-a] pyridine is an organic compound. It has applications in many fields.
    In the field of medicinal chemistry, this compound has a wide range of uses. Due to its unique chemical structure, it has the potential to interact with specific targets in organisms. Many researchers are committed to developing new drugs based on 2-bromoimidazo [1,2-a] pyridine. For example, in the development of antimicrobial drugs, its structure can be modified to enhance its inhibitory effect on specific bacteria, which is expected to solve the problem of bacterial resistance. Or in the exploration of anti-tumor drugs, by optimizing its structure, it is expected to design compounds that can accurately act on tumor cell targets, so as to achieve high-efficiency and low-toxicity anti-tumor efficacy.
    In the field of materials science, 2-bromoimidazo [1,2-a] pyridine also shows certain application prospects. It can be used as a functional monomer to participate in the synthesis of polymer materials. By ingeniously designing the polymerization reaction, it becomes a part of the polymer structure, giving the material unique photoelectric properties. For example, the preparation of materials with special fluorescence properties can be applied to the field of sensors to detect the presence of specific substances, and the sensitive detection of the target can be achieved by the change of its fluorescence intensity.
    In the field of organic synthetic chemistry, 2-bromoimidazo [1,2-a] pyridine is often used as an important synthesis intermediate. Due to the activity of bromine atoms, it can be combined with other organic fragments through various organic reactions, such as nucleophilic substitution reactions, metal-catalyzed coupling reactions, etc., to construct more complex organic molecular structures. Researchers can thus synthesize a series of organic compounds with specific structures and functions, providing an important material basis and method path for the development of organic synthetic chemistry.
    What is the market outlook for 2-bromoimidazo [1,2-a] pyridine
    2 - bromoimidazo [1,2 - a] pyridine is one of the organic compounds. Looking at its market prospects, it has several endpoints.
    In the field of pharmaceutical research and development, this compound has emerged. Its unique structure or biological activity can be used as a potential drug intermediate. In today's pharmaceutical industry, there is a hunger for novel and efficient drugs. Researchers are constantly looking for molecules with special activities to create new drugs to deal with various diseases. 2 - bromoimidazo [1,2 - a] pyridine is expected to give birth to new therapeutic agents due to its unique structure. Therefore, in the pharmaceutical research and development market, its prospects are quite promising.
    Furthermore, in the field of materials science, its potential value is also seen. With the advance of science and technology, the demand for new materials is increasing. This compound may be used to synthesize materials with specific functions due to its own special properties, such as optoelectronic materials. The demand for materials with unique optical and electrical properties in the optoelectronic field is increasing, and 2 - bromoimidazo [1,2 - a] pyridine may be able to meet this demand and find a place in the material synthesis market.
    However, its marketing activities also pose challenges. The process of synthesizing this compound may need to be optimized to reduce costs and yield. If the cost is high, its large-scale application will be limited. And it will take time for the market to recognize and accept new compounds. It is necessary to translate scientific research results into practical applications, and its performance and value will be widely recognized by the market.
    In summary, although 2-bromoimidazo [1,2-a] pyridine faces challenges, it has great potential in fields such as medicine and materials. Over time, through technological innovation and market development, it may be able to shine in related markets and become an important member of the field of organic compounds.