2 Bromo 6 Pyridinecorboxylc
pyridine pyrrole pyrazine piperidine piperazine

2-Bromo-6-pyridinecorboxylc

    Specifications

    HS Code

    670861

    Name 2-Bromo-6-pyridinecarboxylic acid
    Molecular Formula C6H4BrNO2
    Molecular Weight 202.005 g/mol
    Appearance Solid (usually white to off - white)
    Cas Number 5421-31-0
    Melting Point 184 - 188 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Pka Around 2.88

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    General Information
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    Frequently Asked Questions

    As a leading 2-Bromo-6-pyridinecorboxylc supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2-Bromo-6-pyridinecorboxylc?
    2-Bromo-6-pyridinecarboxylic acid, this substance has specific properties and is unique in the field of chemistry. Its shape is either crystalline, the color is pure, or white or nearly white, and the quality is dry and delicate.
    Looking at its melting point, the melting point is significant. At a specific temperature, it gradually melts from the solid state. The value of this temperature is its inherent property, and it is a key sign for chemists to identify and distinguish. The boiling point is also fixed. At this high temperature, the substance converts from the liquid state to gas. This process involves the change of intermolecular forces.
    In terms of solubility, it varies in many common solvents. In polar solvents, such as water, its solubility is limited, or slightly soluble, because the molecular polarity is not compatible with the water molecule. However, in organic solvents, such as alcohols and ethers, the solubility state may be different, or it can be moderately dissolved, depending on the polarity, molecular structure and interaction of the solvent.
    Chemical activity is considerable. Bromine atoms reside in this molecular structure, making it active as halogenated hydrocarbons. In the case of nucleophiles, bromine atoms are easily replaced and other compounds are derived. Pyridine rings are aromatic and give molecules a special electron cloud distribution, which affects the reactivity and selectivity. The existence of carboxyl groups makes them acidic, which can be neutralized with alkali substances to form salts. This reaction is widely used in the field of organic synthesis and drug preparation. The chemical properties of 2-bromo-6-pyridinecarboxylic acid are rich and diverse, and it is a key research object in many disciplines such as organic synthesis and medicinal chemistry. Chemists can use its characteristics to create novel and practical compounds.
    What are the common synthetic methods of 2-Bromo-6-pyridinecorboxylc?
    The method of preparing 2-bromo-6-pyridinecarboxylic acid has various paths. First, it can be started from 6-pyridinecarboxylic acid and brominated with a brominating agent. In this case, liquid bromine is used in combination with a suitable catalyst, such as iron powder or iron tribromide. Under suitable temperature and reaction conditions, liquid bromine can be substituted with 6-pyridinecarboxylic acid, and bromine atoms replace hydrogen atoms at specific positions on the pyridine ring to obtain 2-bromo-6-pyridinecarboxylic acid.
    Second, it can also be started from 2-bromo-pyridine. first, 2-bromo-pyridineis is introduced into the carboxyl group by a suitable method. The Grignard reagent method can be used to react 2-bromopyridine with magnesium to form Grignard reagent, then react with carbon dioxide, and then be acidified. On the basis of the bromine atom at the 2-position of the pyridine ring, the carboxyl group can be successfully introduced at the 6-position, and the final product is 2-bromo-6-picolinecarboxylic acid.
    Furthermore, it is also feasible to selectively remove one of the bromine atoms and introduce the carboxyl group using 2,6-dibromopyridine as the raw material. A suitable nucleophilic reagent can be selected to selectively attack one of the bromine atoms under specific reaction conditions, causing it to leave, and introducing a carboxyl group to obtain the target product 2-bromo-6-pyridinecarboxylic acid. Each method has its own advantages and disadvantages, and the appropriate synthesis path should be carefully selected according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product.
    In what areas is 2-Bromo-6-pyridinecorboxylc applied?
    2-Bromo-6-pyridinecarboxylic acid, which is useful in various fields. In the field of medicinal chemistry, it is often a key raw material for the synthesis of drugs. Due to the unique structure of pyridine ring, bromine atom and carboxyl group, compounds are endowed with specific biological activities. By chemical modification, drugs with antibacterial, anti-inflammatory, anti-tumor and other effects can be prepared to treat various diseases.
    In the field of materials science, it also has important uses. It can be used as a building block for building organic functional materials, and reacts with other compounds to generate materials with special optical and electrical properties. Such materials may be used to prepare electronic devices such as Light Emitting Diodes and sensors, which contribute to the development of electronic technology.
    In the field of organic synthesis chemistry, 2-bromo-6-pyridinecarboxylic acid is a commonly used intermediate. Because of its high reactivity of bromine atoms and carboxyl groups, it can participate in a variety of classical organic reactions, such as nucleophilic substitution reactions, esterification reactions, etc. With this, chemists can synthesize complex organic compounds, expand the boundaries of organic synthesis, and provide possibilities for the creation of new substances.
    In summary, 2-bromo-6-pyridinecarboxylic acid plays an important role in many fields such as medicine, materials, and organic synthesis, and is of great significance to promoting the progress of related science and technology.
    What are the physical properties of 2-Bromo-6-pyridinecorboxylc?
    2-Bromo-6-pyridinecarboxylic acid, the properties of this substance are quite important. Its color is mostly white to light yellow powder, and it looks fine. Under normal temperature and pressure, it is relatively stable, but it needs to be properly stored to prevent deterioration.
    In terms of its melting point, it is about a specific range. This value is of great significance for identifying and purifying this substance. In organic solvents, its solubility varies. In some polar organic solvents, such as methanol and ethanol, it is slightly dissolved, like snowflakes falling in warm water and slowly disappearing; in non-polar organic solvents, such as n-hexane and toluene, it dissolves very little, just like oil droplets entering water, which is out of place.
    Furthermore, its density is also a key physical property. Under specific conditions, there are corresponding values, which depend on its distribution and behavior in different media. The chemical activity of
    2-bromo-6-pyridinecarboxylic acid cannot be underestimated. The presence of bromine atoms, pyridine rings and carboxyl groups makes it able to participate in many chemical reactions, or it is an important raw material for the synthesis of new compounds, and plays a significant role in the field of organic synthesis.
    What is the market price of 2-Bromo-6-pyridinecorboxylc?
    I don't know what the market of 2 - Bromo - 6 - pyridinecorboxylc is. This compound is not familiar to me, and it has not been sold in its price. If you want to know its market value, you can ask for a chemical product trading platform, a chemical raw material supplier or a related industry.
    In today's world, the popularity of chemical products is affected by many factors such as raw material cost, market supply and demand, policy laws, and cost. If the harvest of raw materials is poor, or the cost is high, it will push up the price of the product; and if the market demand is low, supply and demand are low, and the price may decline.
    And different quotients, different degrees, and different packages have different prices. If you want to get all the information, you can search for the suppliers one by one, or check the recent transactions in order to know the general market. However, this is beyond my ability. I hope you can work hard to get the required information.