2 Bromo 6 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-bromo-6-methylpyridine

    Specifications

    HS Code

    583055

    Name 2-bromo-6-methylpyridine
    Molecular Formula C6H6BrN
    Molecular Weight 172.02
    Appearance Liquid (usually)
    Color Colorless to light yellow
    Boiling Point Around 196 - 198 °C
    Density Approx. 1.52 g/cm³
    Solubility Slightly soluble in water, soluble in organic solvents like ethanol, ether
    Odor Pungent odor
    Flash Point Around 79 °C
    Cas Number 2073-33-6

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    General Information
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    Frequently Asked Questions

    As a leading 2-bromo-6-methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-bromo-6-methylpyridine?
    2-%-6-methylpyridine is an important chemical compound, its main use is wide, and it plays an important role in many fields.
    The first is its synthetic field, which can be used as a key ingredient. For example, in the research of some antibacterial compounds, the specialization of 2-%-6-methylpyridine can provide special active groups for the molecules of the compounds, making the compounds more effective and effective, increasing the ability to inhibit bacteria, and helping to develop high-efficiency and low-toxicity antibacterial new compounds for the treatment of infectious diseases.
    Furthermore, it also has outstanding performance in synthesis. With its starting materials, it can synthesize many high-efficiency and high-efficiency products. Its high-quality properties enable it to produce high-quality building materials, bacteria or herbicidal active molecules, which help to improve the quality of crops, reduce the risk of disease and disease, and ensure food safety.
    In addition, there are also outstanding performances in the field of materials. 2-% -6-methylpyridine can be used as a synthetic raw material for special functional materials. For example, it is used to synthesize polymer materials with specific optical and chemical properties. These materials can be used in the manufacture of optical devices such as optical diodes (OLEDs) and solar cells. The development of new optical technologies provides an important material base and promotes the innovation of phase technology.
    Therefore, 2-% -6-methylpyridine has developed irreplaceable uses in various fields such as engineering, engineering, and materials science, and plays an important role in promoting the development of the phase.
    What are the synthesis methods of 2-bromo-6-methylpyridine?
    To prepare 2-hydroxy- 6-methylpyridine, the method is as follows:
    First, it can be obtained by the condensation reaction of acronaldehyde and ammonia. Take an appropriate amount of acronaldehyde, place it in a clean reactor, and add an appropriate amount of ammonia with the assistance of a specific catalyst. The temperature is controlled in a suitable range, usually between [X] ° C and [X] ° C, and attention should be paid to the pressure of the reaction system to maintain at [X] kPa. Under this condition, acronaldehyde and ammonia condensate, and after a series of complex reaction processes, the target product 2-hydroxy- 6-methylpyridine can be obtained. The raw materials for this reaction path are relatively easy to obtain, but the reaction conditions need to be precisely controlled, otherwise the yield and purity will be affected.
    Second, use aldose and ketones as starting materials. If a suitable aldehyde, such as [specific aldehyde], is selected, and methyl ketones, such as [specific methyl ketone], are reacted in a solvent in the presence of an alkaline catalyst. The basic catalyst used can be [specific basic catalyst], and the solvent can be selected as [specific solvent]. The reaction temperature is controlled at about [X] ° C, and the reaction lasts for several hours. During this period, the aldehyde and ketone first condensate, and then go through cyclization, dehydration and other steps to obtain 2-hydroxy- 6-methylpyridine. This method is a little complicated, but common aldehyde and ketone compounds can be used, and the raw materials are widely sourced.
    Third, it is prepared by the substitution reaction of pyridine derivatives. Select suitable pyridine derivatives, such as [specific pyridine derivatives], use their activity check points, under specific reaction conditions, methylate with methylating reagents, and introduce hydroxyl groups with hydroxylating reagents. The methylating reagent used can be [specific methylating reagent], and the hydroxylating reagent can be [specific hydroxylating reagent]. In a suitable reaction solvent, such as [specific solvent], control the reaction temperature, time and other conditions to make the substitution reaction proceed smoothly, and then prepare 2-hydroxy- 6-methylpyridine. This approach has high selectivity for raw materials and harsh reaction conditions, requiring precise regulation to achieve good results.
    What are the physical properties of 2-bromo-6-methylpyridine?
    2-% hydroxyl-6-methylpyridine is an organic compound with unique physical properties and important uses in many fields.
    Looking at its properties, under room temperature and pressure, 2-% hydroxyl-6-methylpyridine is mostly colorless to light yellow liquid. When pure, it is clear and transparent. However, the color may vary depending on the impurities mixed in or storage conditions. Its odor is special, with a certain degree of irritation, close to a fine smell, and can sense a pungent smell. This odor characteristic can be used as a preliminary identification basis.
    Talking about the melting point and boiling point, the melting point of 2-% hydroxyl-6-methylpyridine is about -15 ° C, and the boiling point is between 195 and 198 ° C. The melting point is low, resulting in a liquid state at room temperature; the boiling point is relatively high, indicating that a higher temperature is required to vaporize it. This boiling point characteristic needs to be carefully considered during separation, purification and storage. For example, distillation and purification requires precise temperature control near the boiling point to effectively separate pure 2-% hydroxyl-6-methyl pyridine.
    In terms of solubility, 2-% hydroxyl-6-methyl pyridine is soluble in water and can also be miscible with common organic solvents such as ethanol and ether. This is because its molecular structure contains both hydrophilic hydroxyl groups and oleophilic methyl groups and pyridine rings, which gives it good solubility. In chemical production, using this characteristic, suitable solvents can be selected for extraction and reaction operations.
    In terms of density, 2-% hydroxyl-6-methylpyridine has a density of about 1.08 g/cm ³, which is slightly higher than that of water. When mixed with water, it will sink to the bottom of the water, and this density difference may play a role in some liquid-liquid separation processes.
    In addition, 2-% hydroxyl-6-methylpyridine has certain hygroscopicity, and it is easy to absorb moisture in the air when placed in a high humidity environment. This places higher requirements on storage conditions. It is usually necessary to seal and store it in a dry place to prevent its quality and performance from being affected by moisture absorption.
    What are the chemical properties of 2-bromo-6-methylpyridine?
    2-% cyanogen-6-methylpyridine, which is an organic compound. Its chemical properties are unique and have a variety of characteristics.
    First of all, it is basic. Because the nitrogen atom on the pyridine ring contains lone pairs of electrons, it can accept protons and can form salts in acidic solutions. For example, when interacting with hydrochloric acid, it can form corresponding pyridine hydrochloride salts.
    Second, the presence of cyanyl groups makes it a typical reaction of nitrile compounds. Hydrolyzable, under the catalysis of acid or base, the cyanyl group is gradually converted into carboxyl groups. Taking acid-catalyzed hydrolysis as an example, an amide intermediate is formed first, and then hydrolyzed into carboxylic acids. For example, under the catalysis of sulfuric acid and heating conditions, 2 - (6-methylpyridyl) acetic acid can be obtained by hydrolysis of 2-% cyano-6-methylpyridine.
    Furthermore, the activity of the pyridine ring also affects its reactivity. The electron cloud density distribution of the pyridine ring is uneven, the electron cloud density of the nitrogen atom is relatively low, and the electrophilic substitution reaction is difficult to occur here; the electron cloud density of the meta-site is relatively high, and the electrophilic substitution reaction is more likely to occur in the meta-site. However, compared with benzene, the electrophilic substitution activity of the pyridine ring is still low. In the nucleophilic substitution reaction, the electron cloud density of the carbon atom on the ring is reduced due to the electron absorption of the nitrogen atom on
    In addition, the hydrogen atom on the 2-% cyanogen-6-methylpyridine methyl group has certain activity due to the influence of the pyridine ring and the cyanyl group, and can undergo reactions such as halogenation. In the presence of light or free radical initiators, the hydrogen on the methyl group can be replaced by halogen atoms.
    What are the precautions for storing and transporting 2-bromo-6-methylpyridine?
    2-% hydrazine-6-methylpyridine is an organic compound. When storing and transporting, the following items should be paid attention to:
    First, the storage place should be cool and ventilated. This is because it has certain volatility and chemical activity. High temperature or no ventilation can easily cause it to evaporate and accumulate, or cause chemical reactions, which is even dangerous.
    Second, be sure to keep away from fires and heat sources. 2-% hydrazine-6-methylpyridine is flammable. In case of open flame and high heat, it can cause combustion and explosion. Therefore, fireworks are strictly prohibited in the storage and transportation area, and the temperature control device must be good.
    Third, it should be stored separately from oxidants and acids, and should not be mixed. The chemical properties of 2-% hydrazine-6-methylpyridine make it easy to react violently with oxidants and acids, such as oxidation reaction, acid-base neutralization, etc., or cause explosion, formation of harmful substances and other serious consequences.
    Fourth, the storage container should be well sealed. It can not only prevent its volatilization and escape, pollute the environment, but also avoid the intrusion of external substances, affecting its quality and stability. When transporting, it is also necessary to ensure that the container is free of leakage.
    Fifth, during transportation, the vehicle should run smoothly to avoid bumps and vibrations. Violent shaking or damage to the container causes leakage, and the transportation tool should be equipped with corresponding fire equipment and leakage emergency treatment equipment.
    Sixth, take protective measures when handling and contacting people. Such as wearing suitable gas masks, chemical safety glasses, chemical gloves, etc., to prevent it from contacting the skin and inhaling into the body, harming health.
    In short, 2-% hydrazine-6-methylpyridine has strict requirements on the environment, container and operation during storage and transportation, so as to ensure safety and avoid accidents.