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What are the physical properties of 2-Bromo-6-methoxy-3-nitropyridine?
2-Bromo-6-methoxy-3-nitropyridine is an important compound in the field of organic chemistry. Its physical properties are unique and related to many applications of this compound.
Looking at its appearance, under room temperature and pressure, 2-bromo-6-methoxy-3-nitropyridine is mostly in solid form, usually light yellow to brown crystalline powder. This color and morphological characteristics are crucial for the identification and preliminary judgment of compounds.
When it comes to melting point, the melting point of this compound is in a specific range, about [X] ℃. The determination of melting point is an important indicator for identification and purity judgment. If the purity of the compound is high, the melting point is sharp and the melting range is narrow; conversely, the presence of impurities will reduce the melting point and widen the melting range.
In terms of boiling point, in the atmospheric pressure environment, the boiling point of 2-bromo-6-methoxy-3-nitropyridine is about [X] ° C. The boiling point reflects the volatility of the compound, which is of great significance for the separation, purification and related reaction conditions.
Solubility is also a key physical property. In common organic solvents, 2-bromo-6-methoxy-3-nitropyridine exhibits certain solubility. For example, it is slightly soluble in organic solvents such as ether and acetone, but its solubility in water is very small. This solubility characteristic determines its behavior in different solvent systems, and has a profound impact on the selection of reaction media, product separation, and other operations. The density of
is also a key consideration. Its density is about [X] g/cm ³. This value is indispensable in terms of mass and volume conversion, as well as physical state analysis when mixed with other substances.
In addition, 2-bromo-6-methoxy-3-nitropyridine has certain stability, but because of its bromine, nitro and other functional groups, under specific conditions, such as high temperature, strong acid and alkali environment or the presence of specific catalysts, chemical reactions will also occur, which will affect its physical state and properties.
In conclusion, the physical properties of 2-bromo-6-methoxy-3-nitropyridine are complex and interrelated. In the fields of organic synthesis, drug development and other fields, in-depth understanding and accurate grasp of it is the basis for achieving relevant applications and research goals.
2-Bromo-6-methoxy-3-nitropyridine chemical synthesis methods
To prepare 2-bromo-6-methoxy-3-nitropyridine, the method of chemical synthesis is often followed. The first method is to take 6-methoxy pyridine as the group, after bromination, use a specific brominating reagent, and under suitable reaction conditions, make the bromine atom enter the second position of the pyridine ring. After nitrification, use a suitable nitrifying reagent, control the temperature and reaction environment, so that the nitro group occupies 3 positions. This way, the reagents and conditions need to be carefully selected to increase the selectivity and yield of the reaction. < Br >
Second, or start with 2-bromopyridine, first use a methoxylation reagent, and in an appropriate base and solvent, make the methoxyl group replace the hydrogen at the 6 position of the pyridine ring. The subsequent step is to introduce the nitro group at the 3 position with the nitration of the previous method. During operation, attention should be paid to the conditions of the methoxylation reaction to prevent side reactions.
Third, you can also start from 2-bromopyridine-6-hydroxypyridine, first use the methylation reagent to make the hydroxyl group into a methoxy group, then nitrate it, and add the nitro group at the 3 position. The order and conditions of methylation and nitrification have a great influence on the formation of the product, which must be carefully regulated.
In conclusion, the synthesis of 2-bromo-6-methoxy-3-nitropyridine has its own advantages and disadvantages, and all methods need to be carefully selected in terms of reagent selection and reaction conditions control in order to achieve good synthesis results.
2-Bromo-6-methoxy-3-nitropyridine in what areas
2-Bromo-6-methoxy-3-nitropyridine is widely used in the field of organic synthesis. This compound has a unique structure, in which bromine atoms, methoxy groups and nitro groups coexist on the pyridine ring, making its chemical properties unique.
In pharmaceutical chemistry, it is often an important intermediate. Its structure can be modified by various chemical reactions to construct complex molecular structures with biological activity. For example, by nucleophilic substitution reactions, bromine atoms can be replaced by various nucleophilic reagents, and then functional groups related to drug activity can be introduced to create new drugs and treat various diseases.
In the field of materials science, it may also have applications. The presence of the pyridine ring endows it with a certain conjugated structure, which can affect the electronic effect of methoxy and nitro, or can affect the electronic transport and optical properties of the material. By fine regulation of its structure, materials with specific photoelectric properties can be prepared for use in organic Light Emitting Diodes, solar cells and other devices.
Furthermore, in the field of pesticide chemistry, 2-bromo-6-methoxy-3-nitropyridine may be a key raw material for the preparation of high-efficiency pesticides. After chemical transformation, pesticide products with high toxicity to pests and environmental friendliness can be generated, which can help agricultural pest control and improve crop yield and quality.
What is the market price of 2-Bromo-6-methoxy-3-nitropyridine?
I look at your question, but I am inquiring about the market price of 2-bromo-6-methoxy-3-nitropyridine. However, the price of this product is difficult to determine. The price of the cover often changes for various reasons.
First, the supply and demand of the city is the most critical. If there are many people who want it, but there are few people who supply it, the price will increase; on the contrary, if the supply exceeds the demand, the price may fall. Second, the difficulty of its production also affects it. If the process is complicated, all kinds of rare raw materials are required, or the equipment and technical requirements are quite strict, the cost will be high, and the price will follow. Third, the competitive situation of the city also affects its price. If there are many competitors in the same industry, it is a competition for the market, or there is a move to reduce the price; if the industry is small, or the price can be controlled.
And in different places, the price may vary. Taxes and logistics costs vary from place to place. Goods from far away are transported over long distances, subject to taxes and fees, and the price may be higher than that produced in the vicinity. At different times, the price also changes. Changes in market conditions, the rise and fall of raw material prices, can cause their prices to fluctuate.
To know the exact price, visit a merchant in the chemical raw material market, or consult a professional chemical product trading platform. Real-time prices can be obtained there, which is accurate.
What are 2-Bromo-6-methoxy-3-nitropyridine storage conditions?
2-Bromo-6-methoxy-3-nitropyridine is a chemical substance. Its storage is essential, which is related to the properties of this substance, and also involves safety and quality.
This substance should be placed in a cool and dry place. Cover a cool place to avoid its reaction or decomposition due to high temperature. If it is at high temperature, the chemical activity may increase or cause undesirable changes, damaging its quality. A dry environment is also critical. Due to reactions such as moisture or hydrolysis, its structure will be damaged and its essence will be lost.
Furthermore, it should be stored in a well-ventilated place. Good ventilation can dissipate harmful gases that may escape, ensuring the safety of the environment and protecting the health of the operator. This substance may be toxic, irritating, poorly ventilated, aerated space, and prone to harm.
And it needs to be kept away from fire and heat sources. Because it is flammable or has the risk of explosion, in case of open flame, hot topic, or accident, it will cause fire and explosion.
When stored, it should be stored in separate stores with oxidants, acids, and bases. These substances meet with 2-bromo-6-methoxy-3-nitropyridine, or react violently, creating an unpredictable risk.
And the container must be tightly sealed. Sealing can prevent the volatilization and leakage of substances, and also avoid oxidation and other changes caused by contact with the air, so as to maintain its purity and protect the surrounding environment.
In summary, the storage of 2-bromo-6-methoxy-3-nitropyridine should be in a cool, dry and well-ventilated place, away from fire and heat sources, and stored separately from other dangerous substances, and the container should be sealed to ensure complete security and quality.