2 Bromo 6 Isopropylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Bromo-6-Isopropylpyridine

    Specifications

    HS Code

    134191

    Name 2-Bromo-6-Isopropylpyridine
    Molecular Formula C9H12BrN
    Molecular Weight 214.102 g/mol
    Appearance Liquid (usually)
    Cas Number 112247-42-4
    Boiling Point 222 - 223 °C
    Density 1.292 g/cm³
    Flash Point 94 °C
    Solubility Soluble in organic solvents like dichloromethane, chloroform
    Purity Typically high - purity products available (e.g., 97%+)

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    General Information
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    Frequently Asked Questions

    As a leading 2-Bromo-6-Isopropylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemistry of 2-Bromo-6-Isopropylpyridine?
    2 - Bromo - 6 - Isopropylpyridine is an organic compound with unique chemical properties. Its molecules contain bromine atoms, isopropyl groups and pyridine rings, which give it specific reactivity.
    As far as nucleophilic substitution is concerned, the activity of bromine atoms is quite high. Due to its electronegativity difference, the carbon-bromine bond electron cloud is biased towards bromine, making the carbon atoms partially positively charged and vulnerable to attack by nucleophiles. Nucleophiles such as alkoxides and amines can replace bromine atoms to form new pyridine derivatives. This property is extremely important in the preparation of functional materials and pharmaceutical intermediates in organic synthesis.
    Besides its pyridine ring, it is aromatic and weakly basic. Because there is a conjugated π electron system in the ring, the pyridine ring is stable. When exposed to acid, the nitrogen atom of pyridine can accept protons, exhibit alkalinity, and form salts with acids. This alkalinity can be used for separation and purification, and can also be used as a base catalyst in the reaction to promote specific reactions.
    isopropyl is connected to the pyridine ring, which affects the molecular spatial structure and electron cloud distribution. It is a power supply group, which affects the electron cloud density of the pyridine ring through induction effect, so that the density of the ortho and para-potential electron clouds increases relatively, which affects the selectivity of the check point of the electrophilic substitution reaction. Moreover, the isopropyl group has a large steric barrier, which affects the reagent's proximity to the specific position of the pyridine ring in the reaction, The chemical properties of 2 - Bromo - 6 - Isopropylpyridine are determined by its structure. Nucleophilic substitution, alkalinity and space effect are widely used in organic synthesis and chemical research.
    What are the main uses of 2-Bromo-6-Isopropylpyridine?
    2-Bromo-6-isopropylpyridine is an important chemical substance in organic synthesis. It has a wide range of uses and plays a key role in many fields.
    First, in the field of medicinal chemistry, this substance is often used as a key intermediate. The synthesis of many drugs relies on its participation in reactions to construct molecular structures with specific biological activities. Due to the unique chemical properties of pyridine rings and bromine and isopropyl groups, it can achieve precise modification and construction of drug molecular structures through various chemical reactions, thereby endowing drugs with specific pharmacological activities and pharmacokinetic properties. For example, in the development of some antibacterial and anti-inflammatory drugs, 2-bromo-6-isopropylpyridine can be used as a starting material to introduce key structural fragments through multi-step reactions, so that drug molecules have the ability to target specific biological targets, thereby improving drug efficacy and selectivity.
    Second, in the field of materials science, 2-bromo-6-isopropylpyridine also has important uses. It can be used to synthesize organic materials with special functions, such as optoelectronic materials. Its structural characteristics allow it to participate in polymerization reactions to form polymers with unique optical and electrical properties. Such polymers exhibit excellent carrier transport performance and luminous efficiency in organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices, providing assistance for the performance improvement and development of optoelectronic devices.
    Furthermore, in the field of pesticide chemistry, 2-bromo-6-isopropylpyridine is also an important synthetic raw material. With its chemical activity, a variety of pesticide compounds with biological activities such as insecticidal, bactericidal, and herbicide can be synthesized. By modifying and modifying its structure, the mechanism of action, activity intensity, and environmental compatibility of pesticides can be adjusted to meet the needs of pesticides in different agricultural production scenarios. In conclusion, 2-bromo-6-isopropylpyridine is an indispensable chemical substance in many fields such as medicine, materials, and pesticides due to its unique chemical structure and activity, which is of great significance for promoting the development of various fields.
    What is 2-Bromo-6-Isopropylpyridine synthesis method?
    The synthesis method of 2-bromo-6-isopropylpyridine is an important research direction in the field of organic synthesis. In the past, the synthesis method was often achieved by following a specific organic reaction mechanism and using a variety of chemical reagents and steps.
    One method can start with the derivative of pyridine. First, the pyridine ring is suitably modified and the isopropyl group is introduced through a specific reaction. For example, a suitable pyridine substrate is used to interact with the reagent containing isopropyl group under specific catalyst and reaction conditions. This reaction may require strict control of temperature, reaction duration and reagent ratio to make the isopropyl group precisely connected to the 6-position of the pyridine ring. < Br >
    Then, the bromination reaction is carried out to introduce bromine atoms into the 2-position of the pyridine ring. The bromination process also requires careful selection of bromination reagents, such as bromine, N-bromosuccinimide (NBS), etc. If bromine is used, specific catalysts, such as iron powder, need to be added to catalyze the bromination reaction. The reaction conditions are also crucial, and the choice of temperature and solvent will affect the selectivity and yield of the reaction.
    Or another approach can be taken, first introducing bromine atoms into the pyridine ring, and then adding isopropyl. This approach also requires fine regulation of each step of the reaction to ensure that the reaction proceeds in the desired direction, and to improve the purity and yield of the target product as much as possible. After each step of the reaction, it is often necessary to separate and purify by recrystallization, column chromatography, etc. to obtain pure intermediate products and final 2-bromo-6-isopropylpyridine. The whole process of synthesis, precise control of reaction conditions, and careful selection of reagents are all keys to successful synthesis.
    2-Bromo-6-Isopropylpyridine What are the precautions during storage and transportation?
    2-Bromo-6-isopropylpyridine is an important compound in organic chemistry. In the process of storage and transportation, all precautions should not be ignored.
    First words storage. This compound should be placed in a cool, dry and well-ventilated place. Because it is more sensitive to light and heat, it is advisable to avoid direct light and hot topic environments. If exposed to light or high temperature, it may cause chemical reactions, cause deterioration, and damage chemical properties and purity. Storage should be kept away from fire and heat sources, and fire protection facilities must be complete. In addition, it should be stored separately from oxidizing agents, acids, bases and other substances, and must not be mixed to prevent interaction and lead to danger. At the same time, storage containers must also be carefully selected, and corrosion-resistant materials should be used to ensure that they are well sealed and avoid leakage.
    As for transportation, there are also many points. Before transportation, the packaging must be carefully checked to ensure that the packaging is firm and intact. During transportation, ensure that the container does not tip over, does not damage or leak. Transportation vehicles should be equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. Traffic routes also need to be carefully planned to avoid densely populated areas and important places. Transportation personnel must be professionally trained to be familiar with the properties of this compound and emergency treatment methods. If a leak occurs during transportation, immediate and effective measures should be taken, such as evacuating the crowd, sealing off the scene, and using appropriate materials to absorb or contain the leak, and properly handle it to prevent future disasters.
    In short, during the storage and transportation of 2-bromo-6-isopropylpyridine, it is necessary to exercise caution and strictly follow relevant regulations and operating guidelines to ensure safety and avoid accidents.
    What is the market price of 2-Bromo-6-Isopropylpyridine?
    2-Bromo-6-isopropylpyridine, this product is in the market, and its price varies from time to time, and also varies with quality, quantity and seller. Looking at the city of the past, if you want a fine and pure product, the price may be high; while the crude one, the price is slightly lower.
    In chemical markets, if this product is retailed in small quantities, the price per gram may reach several gold to tens of gold. If the buyer wants a large quantity, such as hundreds of grams or even kilograms, the seller may give a discount due to the high interest rate, and the price per gram may be reduced to several gold.
    And its price is also dependent on supply and demand. If the demand is abundant at the time, but there are few producers, the price will rise; on the contrary, if the production is more and the demand is less, the price will tend to fall. And the price of chemical raw materials is often subject to the accumulation of raw materials, processes, taxes, transportation costs, etc. The price of raw materials rises, the process is difficult, the increase or decrease of taxes, and the fluctuation of transportation costs can cause the price of 2-bromo-6-isopropylpyridine to fluctuate. Therefore, if you want to know its exact price, you should consult chemical companies and observe the current market.