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What are the main uses of 2-bromo-6-cyclopropylpyridine?
2-% hydroxyl-6-cyclohexylaminopurine, also known as agonin, is a plant growth regulator. Its main uses are as follows:
First, in the field of plant tissue culture, agonin has a significant effect. It can effectively induce plant cell dedifferentiation, promote the differentiated cells to restore the ability to divide and form callus. For example, when tissue culture of various flowers, adding an appropriate amount of agonin can greatly improve the success rate of callus induction. At the same time, it can also induce callus redifferentiation, guide callus differentiation to sprout and roots, and help regenerate complete plants. Like in the tissue culture and reproduction of orchids, agonin plays a key role in the differentiation and induction of buds, which greatly improves the reproduction efficiency of orchids.
Second, agonin can effectively delay the aging of plant leaves. It can regulate the distribution of nutrients in plants, so that nutrients are preferentially transported to the parts with agonins. When sprayed on plant leaves with agonin, the leaves can remain green for a long time and maintain high photosynthetic efficiency. For example, in vegetable planting, spraying agonin on the aging leaves can prolong the functional period of the leaves and increase the yield of vegetables.
Third, agonin also plays an important role in regulating the growth and development process of plants. It can affect the apical dominance of plants, make lateral buds grow and develop better, increase the number of branches of plants, and make plants more plump. For example, in the cultivation process of some ornamental plants, the rational use of agonin can adjust the plant shape and improve its ornamental value. At the same time, agonin also has a certain impact on plant flowering and fruiting, which can regulate the flowering period to a certain extent, improve the fruit setting rate, and then affect the development and quality of fruit.
What are the synthesis methods of 2-bromo-6-cyclopropylpyridine?
The synthesis method of 2-% hydroxy- 6-cyclohexylaminopurine, also known as agonin, is as follows:
It can be prepared by reacting 6-chloropurine with cyclohexylamine under appropriate conditions. Place 6-chloropurine in the reaction vessel and add an appropriate amount of solvent, such as some polar organic solvents, to promote the reaction. Then slowly add cyclohexylamine, while strictly controlling the reaction temperature and reaction time. During the reaction, the chlorine atom on 6-chloropurine will be replaced by the amino group in cyclohexylamine, resulting in 2-hydroxy- 6-cyclohexylaminopurine. After the reaction, the product needs to be separated and purified by means such as extraction, crystallization, column chromatography, etc., in order to obtain a high-purity target product.
6-aminopurine can also be used as the starting material. Through a specific hydroxylation reaction, the hydroxyl group is first introduced at the 2 position, and then the obtained product reacts with the cyclohexylation reagent and is connected to the cyclohexyl amino group at the 6 position. During this process, the hydroxylation reaction requires the selection of suitable hydroxylation reagents and reaction conditions to ensure that the reaction mainly occurs at the 2 positions. The cyclohexylation reaction also requires strict control of the reaction parameters to ensure the selectivity and yield of the reaction. Subsequent separation and purification of the product is also required to obtain pure 2-hydroxyl-6-cyclohexylaminopurine.
In addition, there are other synthesis paths, such as starting with compounds containing purine skeletons, and gradually building 2-hydroxyl and 6-cyclohexylamino structures through multi-step reactions, but the specific reaction steps and conditions will be more complex, requiring careful adjustment and optimization according to different starting materials and reaction designs to achieve efficient and high-purity synthesis.
What are the physical properties of 2-bromo-6-cyclopropylpyridine?
2-%E6%BA%B4-6-%E7%8E%AF%E4%B8%99%E5%9F%BA%E5%90%A1%E5%95%B6, is a genus of organic compounds. It has unique physical properties, as detailed below.
Looking at its shape, it is mostly liquid at room temperature and pressure. The shape of this state is due to the moderate degree of interaction between molecules, which is neither discrete like gaseous molecules nor closely arranged like solid molecules.
When it comes to color, it is usually colorless and transparent. This pure color, like clear water, shows the appearance of purity. In many experimental and industrial processes, it is colorless, making it easy to observe the reaction phenomena related to it, and there is no risk of variegated interference.
Smell its smell and emit a special fragrance. This aroma is not pungent and unpleasant, nor is it rich and sweet. It is unique. It can make the sense of smell, and because of its unique smell, it can be used as a characteristic basis in the preparation of certain fragrances or the identification of substances.
As for the boiling point, it is about a specific range. This boiling point value is closely related to the molecular structure and intermolecular forces. Moderate intermolecular forces enable the compound to transform from liquid to gas at a certain temperature. This property can be separated from other substances by distillation according to the difference in boiling points during separation and purification.
Its density is slightly different from that of water. It is either lighter than water or heavier than water, and this difference determines the upper and lower layers when it is mixed with water. If it is lighter than water, it floats on the water surface; if it is heavier than water, it sinks to the bottom. This property can help determine the distribution and direction of substances in chemical reactions or separation operations involving water.
In terms of solubility, in organic solvents, it often exhibits good solubility. Due to the principle of similarity and miscibility, its organic structure allows it to form suitable interactions with many organic solvent molecules, resulting in mutual solubility. However, its solubility in water is relatively limited, because the polarity difference between molecules and water limits its solubility in water.
What are the chemical properties of 2-bromo-6-cyclopropylpyridine?
2-% hydroxyl-6-cyclopropylpyridine is an organic compound with unique chemical properties and is widely used in many fields.
It is alkaline, because the pyridine cyclic nitrogen atom has lone pairs of electrons, which can accept protons, and forms pyridine salts in acidic environments. This alkalinity enables 2-hydroxyl-6-cyclopropylpyridine to react with acids to form corresponding salts, which are widely used in catalysis and pharmaceutical chemistry. For example, in some catalytic reactions, its alkalinity can be used to regulate the pH of the reaction system, which in turn affects the reaction process and selectivity.
The activity of nucleophilic substitution is significant. The electron cloud density distribution of the pyridine ring is uneven, and the electron cloud density at the 2nd and 6th positions is relatively low, which is vulnerable to nucleophilic attack. The presence of hydroxyl groups and cyclopropyl groups further affects the electron cloud distribution on the ring, making nucleophilic substitution reactions easier to occur. In organic synthesis, other functional groups are often introduced through nucleophilic substitution reactions to construct complex organic molecules. For example, halogenated hydrocarbons are used as nucleophiles to react with 2-hydroxyl-6-cyclopropylpyridine under appropriate conditions to achieve functional group transformation and molecular modification.
Hydroxyl groups are active and can participate in a variety of chemical reactions. Esterification reactions can occur, and ester compounds are formed with carboxylic acids or acid anhydrides under the action of catalysts. This property is of great significance in the preparation of ester derivatives in organic synthesis. Some ester compounds with special biological activities can be synthesized by this method. At the same time, hydroxyl groups can be oxidized, and can be converted into other functional groups such as aldehyde groups and carboxyl groups according to different oxidation conditions, providing a variety of paths for organic synthesis.
Cyclopropyl groups have special tension, which affects the stability of the whole molecule and changes the chemical reaction activity. Cyclopropyl reacts easily with nucleophiles or electrophiles. When reacting with nucleophiles or electrophiles, the cyclopropyl ring opens to form new carbon-carbon bond compounds. This ring-opening reaction provides a unique strategy for organic synthesis to construct carbon skeleton structures that are difficult to synthesize by conventional methods. Due to these chemical properties, 2-hydroxyl-6-cyclopropylpyridine is a key intermediate for the synthesis of a variety of drugs in the field of medicine, used to develop drugs with specific biological activities and pharmacological effects; in the field of materials science, it can be used as a building block to synthesize functional organic materials to meet different application needs.
What is the price of 2-bromo-6-cyclopropylpyridine in the market?
Today there is dihydroxyhexocyclopropyl urea, what is the price in the market? This question is quite crucial, and it is related to the trade-off of business.
However, if you want to know its price, it cannot be conjectured. It is necessary to observe all the reasons for the situation. First, observe the supply and demand of this product. If there are many people in the world who want it, but there are few producers, the price will be high; if the supply exceeds the demand and fills the city, the price will drop. Second, investigate its origin. Different places have different costs for producing this product. If it is transported from a distance, the price will be higher; if it is produced nearby, the freight will be saved, and the price will be cheaper. Third, it depends on its quality. Those who are of high quality are willing to buy it for a lot of money; those who are of inferior quality are difficult to increase. < Br >
Looking at the current commercial regulations, the competition in the same industry also affects the price. Businesses compete for the market, or reduce their prices to attract customers; if there is no semicolon in a unique company, the price can be set by yourself.
Although I have not seen the price of dihydroxyhexocyclopropyl urea in the market, I have deduced it based on commercial common sense. The price is determined by supply and demand, origin, quality and competition. If you want to know the exact price, you must go to the market in person, consult the merchants, or check the report of the business situation, and you can get it. However, today it is only reasonable, and the price may vary from time to time and place to situation, so it cannot be generalized.