2 Bromo 6 Chloro 3 Methyl 5 Nitropyridine
pyridine pyrrole pyrazine piperidine piperazine

2-bromo-6-chloro-3-methyl-5-nitropyridine

    Specifications

    HS Code

    326074

    Chemical Formula C6H4BrClN2O2
    Molecular Weight 251.466
    Appearance Solid (likely yellow - colored due to nitro group)
    Physical State At Room Temp Solid
    Odor Typical of halogen - and nitro - containing heterocycles, pungent
    Melting Point Data may vary, but usually in the range where organic halonitroheterocycles melt, e.g., 80 - 120°C (estimated)
    Boiling Point Elevated boiling point due to polar groups, perhaps around 280 - 320°C (estimated)
    Solubility In Water Low solubility, due to non - polar pyridine ring and hydrophobic halogen and nitro groups
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, ethyl acetate
    Density Greater than 1 g/cm³ (estimated, due to presence of heavy halogen atoms)
    Stability Stable under normal conditions, but can react with strong reducing agents, strong bases, and nucleophiles

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    General Information
    Where to Buy 2-bromo-6-chloro-3-methyl-5-nitropyridine in China?
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    Frequently Asked Questions

    As a leading 2-bromo-6-chloro-3-methyl-5-nitropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-bromo-6-chloro-3-methyl-5-nitropyridine?
    2-Bromo-6-chloro-3-methyl-5-nitropyridine is also an organic compound. Its main use covers the field of organic synthesis.
    In pharmaceutical chemistry, it is often used as a key intermediate. It can be converted into biologically active molecules through specific chemical reaction pathways for the development of new drugs. For example, it may participate in the construction of the core structure of drug molecules, by modifying the surrounding substituents, adjusting the interaction between drugs and biological targets, and then optimizing the efficacy and selectivity of drugs.
    In the field of materials science, it also has its uses. Because of its unique chemical structure, it may participate in the preparation of functional materials. For example, by reacting with other organic or inorganic compounds, materials with special electrical, optical or thermal properties can be used in the manufacture of devices such as Light Emitting Diodes and sensors.
    Furthermore, in the field of pesticide chemistry, it is also an important starting material. Pesticide ingredients with insecticidal, bactericidal or herbicidal activities can be prepared through a series of reactions to assist agricultural pest control and ensure crop growth and yield.
    In summary, 2-bromo-6-chloro-3-methyl-5-nitropyridine has critical uses in many fields related to organic synthesis, such as medicine, materials, and pesticides, and promotes technological progress in various fields and Product Research & Development.
    What are 2-bromo-6-chloro-3-methyl-5-nitropyridine synthesis methods?
    The synthesis method of 2-bromo-6-chloro-3-methyl-5-nitropyridine is often used by the number method.
    First, pyridine is used as the starting material. Pyridine is methylated to obtain 3-methylpyridine. Appropriate methylating reagents, such as iodomethane and base, can be used to introduce methyl groups at specific positions on the pyridine ring under suitable reaction conditions. Then, 3-methylpyridine is halogenated. 2-Bromo-6-chloro-3-methylpyridine can be obtained by introducing bromine and chlorine atoms at specific positions in the pyridine ring with brominating agent and chlorinating agent under suitable reaction conditions. Among them, the reaction conditions of bromination and chlorination need to be precisely regulated to ensure the selectivity of the introduction of halogen atoms. Finally, 2-bromo-6-chloro-3-methylpyridine is nitrified. The target product 2-bromo-6-chloro-3-methyl-5-nitropyridine is obtained by introducing a nitrifying reagent, such as a mixed acid (nitric acid mixed with sulfuric acid), into the pyridine ring at a specific temperature and reaction time. In this process, the control of the conditions of the nitrification reaction is crucial, and it is related to the position of nitro introduction and the reaction yield.
    Second, it can be started from other compounds containing pyridine structures. For example, the functional group on the pyridine derivative is first converted into an active group that can be used to introduce bromine, chlorine, methyl, and nitro groups. Classical organic reactions such as nucleophilic substitution reaction and electrophilic substitution reaction can be used to gradually construct the structure of the target molecule. Through a series of reaction steps, the reaction conditions and the amount of reagents are precisely controlled, and the functional groups are introduced in an orderly manner to finally synthesize 2-bromo-6-chloro-3-methyl-5-nitropyridine. This method requires careful design of the structure of the starting pyridine derivative to facilitate the smooth progress of subsequent reactions and the efficient synthesis of the target product.
    What are the physical properties of 2-bromo-6-chloro-3-methyl-5-nitropyridine?
    2-Bromo-6-chloro-3-methyl-5-nitropyridine, this substance is an organic compound with specific physical properties. Its shape is mostly crystalline powder, stable at room temperature, and may change under specific conditions.
    Looking at its melting point, due to the interaction of many groups in the molecular structure, the intermolecular forces are different, and the melting point is within a certain range. Usually, the exact value can be obtained by accurate experimental determination. The boiling point is also affected by factors such as intermolecular forces and molecular weights. Each atom and the group cooperate to make the compound need a specific energy to boil, so it has a specific boiling point.
    In terms of solubility, according to the principle of similarity dissolution, it is a polar molecule. In polar organic solvents such as dichloromethane, N, N-dimethylformamide, it has good solubility due to the interaction with solvent molecules; in water, due to the weak intermolecular force between water and the compound, the solubility is poor.
    In addition, its density is closely related to molecular weight and molecular structure. The molecular arrangement and the type and quantity of atoms determine the mass per unit volume, that is, the density. The physical properties of this compound have a profound impact on its application in organic synthesis, drug development and other fields. Researchers need to rationally design reactions and choose separation and purification methods according to these properties.
    What are the chemical properties of 2-bromo-6-chloro-3-methyl-5-nitropyridine?
    2-Bromo-6-chloro-3-methyl-5-nitropyridine, this is an organic compound. Its chemical properties are unique and quite eye-catching.
    Let's talk about its halogen atom properties first. The molecule contains bromine and chlorine atoms, which are very active. Bromine atoms, as larger halogen atoms, can be replaced by many nucleophilic reagents in nucleophilic substitution reactions. In case of hydroxyl negative ions, bromine atoms may be replaced by hydroxyl groups to form corresponding alcohol derivatives. Although the chlorine atom is slightly smaller, it is also active. Under certain conditions, it can also participate in nucleophilic substitution, or react with metal reagents to generate intermediates such as Grignard reagents, thus expanding new paths for organic synthesis. The existence of
    methyl is also of great significance. Methyl is a power supply group, which can change the electron cloud distribution on the pyridine ring, so that the electron cloud density of the pyridine ring increases, especially in the ortho and para-positions, which affects the reactivity of the molecule to a certain extent. For example, in the electrophilic substitution reaction, the methyl group has a significant role in positioning the reaction check point, guiding the electrophilic reagent to attack its ortho and para-positions, and the reaction direction is left and right. < Br >
    Nitro is a strong electron-absorbing group, which strongly reduces the electron cloud density of the pyridine ring, making the pyridine ring more susceptible to nucleophilic attack. At the same time, nitro can participate in the reduction reaction, and under the action of suitable reducing agents, it may be reduced to amino groups. This reaction provides an effective way for the synthesis of amino-containing pyridine derivatives.
    2-bromo-6-chloro-3-methyl-5-nitropyridine Due to the synergy of these groups, it exhibits rich and diverse chemical properties and has great potential in the field of organic synthesis, which can be used to prepare a variety of organic compounds with different functions.
    What is the price range of 2-bromo-6-chloro-3-methyl-5-nitropyridine in the market?
    2-Bromo-6-chloro-3-methyl-5-nitropyridine is in the market, and its price range is difficult to determine. The price of this product often varies for many reasons. First, the scale of production is different. If large-scale production, the cost may decrease, and the price will also decrease; if it is produced in small quantities, the cost will be high, and the price will be high. Second, the price of raw materials also has an impact. If the price of the raw materials required is high, the price of the product will also rise; if the price of raw materials falls, the price may decrease. Furthermore, the supply and demand situation in the market, if the demand exceeds the supply, the price will rise; if the supply exceeds the demand, the price will be depressed.
    Looking at the method of "Tiangong Kaiwu", although the price of this product is not detailed, it is common sense that the price of chemical products varies from time to time and from city to city. According to the price changes of chemical products in the past, the price of 2-bromo-6-chloro-3-methyl-5-nitropyridine varies from a few yuan to tens of yuan per gram or from a few yuan per gram. Prices vary in different markets and at different times. Buyers need to check the market conditions carefully and compare the prices of various companies before they can get a suitable price. However, if you want to know the price, you need to consult the supplier of chemical raw materials in detail to obtain real-time price information.