2-bromo-5-(methylthio)pyridine

The physical properties of 2-% ether-5- (acetyl) alkane are as follows:
This substance is mostly liquid at room temperature, has a certain volatility, and is often accompanied by a special smell, like a slight fruity aroma and ether-specific smell. Its density is lighter than that of water, about 0.8-0.9 times that of water, and it will float on the water surface when placed in water, and the two are insoluble.
In terms of solubility, this substance can be well miscible with most organic solvents, such as ethanol, acetone, chloroform, etc., showing high affinity with organic systems; but it is almost insoluble in water, due to the non-polar characteristics of its molecular structure. The melting point of
is in a lower range, generally between -50 ° C and -30 ° C. It is easy to solidify into a colorless and transparent waxy solid in a low temperature environment; the boiling point is relatively moderate, roughly 120 ° C - 150 ° C. By controlling the temperature, the substance can be transformed from liquid to gaseous state. This characteristic is quite critical in the process of separation and purification.
The substance has good flammability. When burning, the flame is light blue, and the combustion process is relatively smooth. Mixing its steam with air can form an explosive mixture. In case of open flame and high heat, it can cause combustion and explosion. Therefore, special attention should be paid to fire and explosion prevention when storing and using. At the same time, it has certain chemical stability, but under certain conditions, such as strong acid, strong alkali environment or high temperature, light, etc., chemical reactions may occur, causing changes in its structure and properties.

2-% -5- (methylcarbonyl) pyridine is a characteristic compound. Its chemical properties are rich, and it has shown important uses in many domains.
First of all, its acidic properties. Due to the existence of a methyl carbonyl group, this compound can produce molecules under suitable conditions, showing a certain acidity. In a specific environment, the compounds on the methyl carbonyl group can be biodegradable, and the acid phase can be reactive.
Furthermore, in terms of their carbonyl properties, the carbonyl group of the 5- (methylcarbonyl) moiety is reactive. Carbonyl oxide makes the carbonyl carbon atom positive and vulnerable to nuclear attack. This property makes the carbon compound can be reactive such as nuclear addition. For example, it can contain the nucleus of the active pyridine, such as alcohols and amines, to generate a reaction reaction, generating an addition of the phase.
In addition, the presence of pyridine also gives the compound its special aromaticity. The nitrogen atom of pyridine has solitary molecules, which can interact with molecules, such as the formation of pyridine and the like. And the aromaticity of pyridine makes the compound have a certain degree of characterization, and the same also affects its anti-activity and anti-location. In some reactions, pyridine can be used as a recipient or donor, and the transfer process of pyridine.
Furthermore, the substituent position of the compound also affects its integration. The position of the phase of 2-alkyl-5- (methylcarbonyl) determines the molecular properties of the molecule, which affects its inverse activity. In the synthesis of organic compounds, according to this characteristic, a reasonable inverse pathway can be made, and the functionalization of a specific position can be achieved to obtain the desired target.
Therefore, 2-5-methylcarbonyl-pyridine exhibits rich chemical properties due to its multi-functional and special molecular properties, and has great potential in the fields of synthetic and chemical processes.

The main use of 2-% -5- (ethylphenyl) pyridine is for chemical synthesis, chemical research and other fields.
In chemical synthesis, due to its special chemical properties, it can be used as an important chemical synthesis. It can interact with other compounds by means of a series of chemical reactions to create more complex molecules with specific functions. For example, in the specific chemical compounds required for some novel materials, 2-% -5- (ethylphenyl) pyridine can be used as a starting material, and a multi-step reaction is used to introduce specific functional groups, which can obtain the required molecular properties of the target material.
In the field of chemical research, this compound also has a value. The physicochemical industry can modify the product according to its characteristics. Its molecules can be modified by specific biological or enzyme interactions, and it is expected to develop new therapeutic substances. For example, specific biological targets for certain diseases are based on the parent nucleus of 2-% -5- (ethylphenyl) pyridine, and specific active groups are introduced to increase the effectiveness of the target, improve the effectiveness of the product, and reduce side effects.
In addition, in the material science, there may also be a use force. It may be possible to synthesize certain polymeric materials by transforming them into polymers and controlling the physical properties of materials, such as mechanical properties, qualitative properties, and optical properties, etc., in order to meet the special needs of material properties in different engineering fields. Moreover, 2-% -5- (ethylphenyl) pyridine plays an indispensable role in many important fields, providing important basic materials for scientific research and development.

To prepare 2-hydroxy- 5- (formyl) pyridine, there are three methods.
First, pyridine is used as the beginning and is replaced by electrophilic substitution. The nitrogen atom of pyridine is electron-absorbing, which makes the electron cloud density on the ring uneven. The electron cloud density at the α and γ positions is low, and the β position is relatively high. Therefore, halogenated reagents such as bromine and chlorine can interact with pyridine under specific conditions to obtain β-halogenated pyridine. After cyanidation, the halogen atom is replaced with a cyanide group with a cyanide reagent such as sodium cyanide to obtain β-cyanopyridine. Then hydrolyzed, under the catalysis of acid or base, the cyano group is converted into a carboxyl group. Finally, after reduction, the carboxyl group is reduced to hydroxymethyl group with a strong reducing agent such as lithium aluminum hydride, and partially oxidized. If a mild oxidizing agent is used, the hydroxymethyl group can be partially oxidized to formyl group to obtain the target product.
Second, use 2-methyl-5-nitropyridine as raw material. First, the nitro group is reduced to iron powder, hydrochloric acid and other reduction systems to convert the nitro group into an amino group to obtain 2-methyl-5-aminopyridine. After diazotization, sodium nitrite and hydrochloric acid are used to convert the amino group into a diazo salt at low temperature. After the Sandmeier reaction, with the catalysis of cuprous chloride, cuprous bromide, etc., the diazo group is replaced by the halogen atom to obtain 2-halomethyl-5-halopyridine. Then cyanide, the cyano group replaces the halogen atom to obtain 2-cyanomethyl-5-cyanopyridine. Hydrolyze the cyanyl group to the carboxyl group, and then the carboxyl group is partially reduced to the hydroxymethyl group, and the hydroxymethyl oxide is the formyl group, which is also obtained.
Third, with a suitable heterocyclic compound as the starting material, the cyclization reaction is carried out. For example, a chain compound containing nitrogen and oxygen is used to form a ring in the molecule under the catalysis of acid or base, heating and other conditions to construct a pyridine ring, and hydroxymethyl and formyl groups are introduced at the same time. The reaction process requires precise control of conditions, adjusting the ratio of reactants, temperature, time, etc., so that the reaction proceeds in the direction of generating 2-hydroxy- 5- (formyl) pyridine.
These three methods have their own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider the availability of raw materials, cost, difficulty of reaction conditions and other factors to choose the appropriate method.

2-% calico-5- (methylyl) should pay attention to the following things when it is stored and stored:
First, this physical property may be special, and it should be stored in the same way. It is dry and well-connected. It must not be placed in a place where the tide or energy can cause the biochemical reaction to change its properties and affect its original effect. For example, if it is damp, or some of its components are hydrolyzed, it will be destroyed.
Second, on the way, you must be careful. Avoid strong shock collisions, because it may have a certain sensitivity. Under the collision of strong shocks, or the reaction of unexpected periods, it may even be dangerous. For example, there have been cases of explosions caused by collisions between objects, which is inevitable.
Third, the degree of stability of the environment also needs to be controlled. High density, or accelerate its decomposition, and low density, may also make it biologically rational changes, such as solidification, etc., which affect its use. Therefore, according to its characteristics, it is necessary to maintain an appropriate degree of stability.
Fourth, this or some substances are corrosive or reactive. Therefore, the materials used for storage containers or tools need to be carefully selected to ensure the safety of their storage.
Fifth, storage and storage, and ban fire. Due to its flammability or oxidation, it is easy to cause fire or even explosion accidents in case of open flames, high temperatures, etc., endangering human life and safety.