2-bromo-5-(methylsulfonyl)pyridine

2-% hydroxyl-5- (methylsulfonyl) pyridine, the physical properties of this substance are as follows:
Its appearance is usually solid, or in a liquid state under specific conditions. In terms of color, it is mostly white to light yellow powder or crystalline solid, with a more delicate appearance and may show a certain luster under light.
In terms of solubility, it has a certain solubility in common organic solvents such as methanol, ethanol, dichloromethane, etc. This characteristic is due to the fact that the functional groups contained in its molecular structure can form specific interactions with organic solvent molecules, such as hydrogen bonds, van der Waals forces, etc. However, the solubility in water is relatively poor, because the overall hydrophobicity of the molecule is relatively strong, with only some polar groups, it is difficult to fully interact with water molecules to achieve good dissolution.
Melting point is also one of its important physical properties. After precise experimental determination, its melting point is in a certain temperature range. This temperature range is of great significance for substance identification and purity judgment. The melting point of the substance with different purity may have slight differences, following the laws of physics and chemistry. The higher the purity, the closer the melting point to the theoretical value, and the narrower the melting range.
In terms of boiling point, due to the intermolecular force, it has a corresponding boiling point under specific pressure conditions. By measuring the boiling point, it can also assist in understanding its physical properties and chemical structure stability and other information. < Br >
Density is also a parameter that characterizes its physical properties. Under given conditions, the density is relatively stable and can be used for the identification of substances and the calculation of related physical processes.
In addition, the refractive index of the substance also has a specific value. The refractive index reflects the refractive properties of light propagating in the substance, and is closely related to the molecular structure of the substance and the distribution of electron clouds. It has reference value for analyzing its structure and purity.

The common synthesis methods of 2-% nitrile-5- (methacryloxyethyl) pyridine buzzing salt are as follows:
First, 2-methylpyridine and acryloyl chloride are used as raw materials. First, 2-methylpyridine is placed in a reaction vessel, and acryloyl chloride is slowly added dropwise under low temperature and stirring conditions. This process requires attention to the control of the reaction temperature to avoid the increase of side reactions due to excessive temperature. After the dropwise addition is completed, it is heated to a suitable temperature for reaction. The reaction time depends on the actual situation, usually several hours. After the reaction is completed, the product can be purified by means of reduced pressure distillation and recrystallization to obtain 2-nitrile-5- (methacryloxyethyl) pyridine buzzing salt. The reaction principle is that the nitrogen atom of 2-methylpyridine undergoes nucleophilic substitution of the carbonyl group of acryloyl chloride.
Second, 2-cyanopyridine and glycidyl methacrylate are used as raw materials. 2-cyanopyridine and glycidyl methacrylate are put into the reactor in a specific ratio, and an appropriate amount of catalyst, such as quaternary ammonium salt catalyst, is added. Under a certain temperature and pressure, the two undergo ring-opening addition reaction. The reaction process needs to be closely monitored during the reaction. After the reaction reaches the desired level, the product is separated and purified by extraction, column chromatography and other methods. This method takes advantage of the activity of 2-cyanopyridine and the epoxy structure of glycidyl methacrylate, which is easy to open the ring.
Third, 5-chloromethyl-2-cyanopyridine and hydroxyethyl methacrylate are used as raw materials. Mix 5-chloromethyl-2-cyanopyridine and hydroxyethyl methacrylate in the reaction system, add acid binding agents, such as potassium carbonate, etc. Under heating and stirring, a substitution reaction occurs, and the chloride ion is replaced by the hydroxyl group of hydroxyethyl methacrylate. After the reaction is completed, the pure 2-nitrile-5- (methacryloxyethyl) pyridine buzz salt is obtained through washing, drying, rectifying and other processes. This reaction path utilizes the principle of substitution reaction between halogenated hydrocarbons and alcohols.
Different synthesis methods have their own advantages and disadvantages. In practical application, the most suitable synthesis method should be selected according to the availability of raw materials, cost, difficulty of reaction conditions and purity requirements of the product.

2-% hydroxyl-5- (methylthiazolyl) This substance is used in various fields. In the field of medicine, it can be a key raw material for the synthesis of many drugs. Due to its specific chemical structure, it can participate in the construction of molecules with special pharmacological activities. For example, in the development of antibacterial drugs, it may be used as an active group to enhance the inhibitory and killing effectiveness of drugs against pathogens.
In the chemical industry, it also plays an important role. It can be used to prepare organic materials with special properties. Due to its structural properties, it endows materials with unique physical and chemical properties, such as improving material stability, improving its solubility or enhancing its reactivity. In the synthesis of new polymer materials, it may be an indispensable monomer or modifier to optimize material properties and meet different industrial needs.
In the field of agriculture, it may have potential application value. Or it can be appropriately modified and developed into a pesticide component. By virtue of its specific mechanism of action against pests, it exerts its insecticidal, bactericidal or herbicidal effects to help agricultural pest control and ensure crop yield and quality.
In the process of scientific research and exploration, 2 -% hydroxyl-5 - (methylthiazolyl) is an important research object. By studying its reaction characteristics, structure and performance relationships, researchers expand the knowledge boundary of organic chemistry, provide ideas for the development of new synthesis methods and reaction paths, and promote the progress and development of chemistry.

The price of "2-hydroxyl-5- (methylthiazolyl) " as you said is difficult to determine in the market. The price often varies due to many reasons.
First, the price of raw materials is the main reason. If the raw materials used to generate this "2-hydroxyl-5- (methylthiazolyl) " are abundant in production, difficult to harvest, and abundant in demand, the price can rise or fall. If the raw materials are abundant and easy to harvest, and the seekers are not available, the price will be flat; on the contrary, if the raw materials are rare and expensive, and there are many seekers, the price will rise.
Second, the technology of production is also crucial. If the method of making this is refined and easy, cost-effective and efficient, the price may be close to the people; if the technology is difficult to make, special equipment is required, money and time-consuming, the price will be high.
Third, the demand and supply of the city will also affect its price. If there is a large demand for "2-hydroxyl-5- (methylthiazolyl) " in the city, and there are few suppliers, the price will be high; if there are few applicants, the supply will exceed the demand, the price will drop.
Fourth, the place and time are different, and the price is also different. For distant things, when they arrive through transshipment, their fees will increase, and the price will increase accordingly. Changes in time, such as seasons, decrees, etc., can cause prices to fluctuate.
Combined with various factors, the market price of "2-hydroxyl-5- (methylthiazolyl) " fluctuates roughly between [X] and [X], but this is only an approximate number. The actual price still needs to be considered in detail.

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2-hydroxy- 5 - (methylsulfonyl) pyridine Its storage conditions are quite critical. This compound has specific chemical properties and needs to be properly stored to prevent deterioration and affect its effectiveness.
The first priority is the drying of the environment. Moisture can easily cause chemical reactions such as hydrolysis of many compounds, which can damage their structure and properties. Therefore, it should be stored in a dry place, and a desiccant can be prepared for storage, such as silica gel, to absorb water vapor in the environment and maintain a dry atmosphere.
The second is temperature control. Generally speaking, it is recommended to store in a cool and low temperature place, away from high temperature environment. High temperature can accelerate the movement of molecules, cause the rate of chemical reactions to accelerate, or cause the compound to decompose, polymerize, etc. Generally, the room temperature is slightly lower, such as between 2-10 ° C. The specific temperature needs to be accurately determined according to its stability.
Furthermore, light also has an effect. Some compounds are sensitive to light and easily cause photochemical reactions under light. Therefore, they should be placed in a dark container, such as a brown glass bottle, to block light and reduce the possibility of photochemical reactions.
In addition, when storing, it should be ensured that it is isolated from other substances that may react. Because its chemical structure contains specific functional groups, or reacts with certain oxidants, reducing agents, acids, bases, etc. Therefore, it needs to be stored separately and clearly marked on the storage container to prevent mismixing.
In this way, following the principles of drying, low temperature, protection from light and isolation, 2-hydroxy- 5- (methylsulfonyl) pyridine can be properly stored to make its performance stable for subsequent use.