2 Bromo 5 Chloropyridine 4 Carboxaldehyde
pyridine pyrrole pyrazine piperidine piperazine

2-Bromo-5-chloropyridine-4-carboxaldehyde

    Specifications

    HS Code

    890695

    Chemical Formula C6H3BrClNO
    Molar Mass 220.45 g/mol
    Appearance Solid (likely)
    Physical State At Room Temperature Solid
    Solubility In Water Low (aromatic aldehydes with halogens are generally sparingly soluble in water)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, etc.
    Hazard Class Irritant (halogen - containing organic compounds can be irritants), may be toxic

    As an accredited 2-Bromo-5-chloropyridine-4-carboxaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing
    Storage
    Shipping
    Free Quote

    Competitive 2-Bromo-5-chloropyridine-4-carboxaldehyde prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365036030

    Email: info@alchemist-chem.com

    General Information
    Where to Buy 2-Bromo-5-chloropyridine-4-carboxaldehyde in China?
    As a trusted 2-Bromo-5-chloropyridine-4-carboxaldehyde manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Bromo-5-chloropyridine-4-carboxaldehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-Bromo-5-chloropyridine-4-carboxaldehyde?
    2-Bromo-5-chloropyridine-4-formaldehyde, this is an organic compound with unique physical properties. Its properties are often solid, and its appearance may be white to light yellow powder. This color state is common in many organic compounds.
    As far as the melting point is concerned, the exact value needs to be determined experimentally, and it is affected by factors such as purity, but the approximate range can be speculated from similar compounds. The melting point of pyridine aldehyde compounds may be between tens of degrees Celsius and 100 degrees Celsius. The melting point of this compound may also be in this range, and the actual measurement shall prevail.
    In terms of solubility, because the molecule contains polar aldehyde groups, it has a certain solubility in polar organic solvents such as methanol, ethanol, and dichloromethane. The aldehyde group can interact with polar solvents to form hydrogen bonds and improve dissolution. In water, because the molecule contains halogen atoms and pyridine rings, the overall hydrophobicity is strong, the solubility is relatively small, and only slightly soluble.
    Volatility, because it is a solid and relatively large molecular weight, the volatility is weak at room temperature and pressure. Compared with small molecule organic compounds, its intermolecular force is stronger, and it is difficult for molecules to escape into gases, so it is not easy to volatilize.
    2-bromo-5-chloropyridine-4-formaldehyde The physical properties are affected by bromine, chlorine atoms, pyridine rings and aldehyde groups in the molecular structure. These properties are essential for their separation, purification, and choice of reaction conditions in the fields of organic synthesis and medicinal chemistry.
    What are 2-Bromo-5-chloropyridine-4-carboxaldehyde synthesis methods?
    The method of synthesizing 2-bromo-5-chloropyridine-4-formaldehyde has been explored by many scholars in the past. One common method is to use pyridine derivatives as starting materials through halogenation and formylation. First, the pyridine is halogenated at a specific position, and bromine and chlorine atoms are introduced. Suitable halogenation reagents can be used. Under suitable reaction conditions, such as controlling temperature and solvent, the bromine and chlorine atoms precisely fall at the target check point. Then formylation is carried out to achieve the purpose of generating aldehyde groups. During formylation, a specific formylation reagent is selected, and a catalyst is used to control the reaction environment, so that the reaction can be efficiently carried out in the direction of generating 2-bromo-5-chloropyridine-4-formaldehyde.
    Another way is to start with a heterocyclic compound containing the corresponding substituent and convert it through a multi-step reaction. In the meantime, it may involve cyclization, substitution and other steps. First, the pyridine ring system is constructed by clever cyclization reaction, and at the same time, the groups that can be converted into bromine, chlorine and aldehyde groups are preset on the ring. Then by substitution reaction, the preset groups are converted into bromine, chlorine and aldehyde groups in sequence. In this process, each step of the reaction needs to be carefully regulated to ensure the selectivity and yield of the < Br >
    Or you can start from easily available simple compounds and combine them in multiple steps. First construct the relevant structural fragments containing bromine, chlorine and aldehyde groups, and then splice the fragments through appropriate reactions to obtain 2-bromo-5-chloropyridine-4-formaldehyde. This strategy requires careful consideration of the fragment linking reaction, selection of linking reagents and conditions, so that each fragment can be precisely connected to obtain the target product. All these synthetic methods require fine operation and insight into the reaction mechanism to achieve the purpose of synthesis.
    2-Bromo-5-chloropyridine-4-carboxaldehyde in what areas
    2-Bromo-5-chloropyridine-4-formaldehyde, which is widely used in the field of medicinal chemistry, is mostly a key intermediate for the synthesis of many drugs. Due to the unique structure of pyridine ring, halogen atom and aldehyde group, complex and biologically active compound structures can be constructed through various chemical reactions. For example, derivatives with different functional groups can be synthesized through nucleophilic substitution reaction, where aldehyde groups interact with nucleophiles containing nitrogen and oxygen, which is crucial in the development of antibacterial and antiviral drugs, helping to create novel and efficient therapeutic drugs.
    In the field of materials science, 2-bromo-5-chloropyridine-4-formaldehyde is also useful. It can participate in the preparation of specific optoelectronic materials. Pyridine rings and halogen atoms can affect the electron cloud distribution and energy level structure of materials, giving materials unique optical and electrical properties, such as for the synthesis of organic Light Emitting Diode (OLED) materials, or to improve the luminous efficiency and stability of devices.
    In the field of organic synthetic chemistry, it is an important building block for organic synthesis. With its multiple activity checking points, it can carry out halogenated hydrocarbon-related reactions, condensation reactions involving aldehyde groups, etc., and realize the construction of various complex organic molecules. It provides an effective way for the synthesis of organic compounds with special structures and properties, and promotes the development of organic synthetic chemistry.
    What is the market price of 2-Bromo-5-chloropyridine-4-carboxaldehyde?
    I don't know what the market is for 2 - Bromo - 5 - chloropyridine - 4 - carboxaldehyde. This compound is not a normal thing, and its quality is often affected by many factors.
    First, the degree is very important. If its degree is very high, it will be high enough for scientific research. If you want to use it in the synthesis or research of refined chemicals, you need something that needs to be high, and the supplier must ask for it. Because of its improvement process, it requires exquisite technology and multiple steps, and the cost is high.
    Second, the demand for this product also affects the price. If the market is in high demand for this product, such as a new research product that needs a lot, and the supply is limited, it will rise. On the contrary, if the demand is weak, the supply is sufficient, and the cost of production is reduced.
    Third, the cost of production also affects the price. The cost of raw materials, the method of synthesis, and the cost of production are all among them. If the raw materials are rare and available, or the synthesis step is complex, it requires a special price, and the price is not cheap. If it can be produced in a large scale, the cost of production may be reduced.
    Fourth, the difference between suppliers also makes the price different. Different suppliers have different prices due to factors such as technology, cost control, and branding. Well-known big brands, because of their trust and quality, or higher than small.
    If you want to know the market, you need to identify suppliers and compare them to get a rough estimate. Or you can check the product trading platform and industry report to see the market. However, it often floats, and you need to make a note to get the latest update.
    What are 2-Bromo-5-chloropyridine-4-carboxaldehyde storage conditions?
    2-Bromo-5-chloropyridine-4-formaldehyde is an important compound in organic chemistry. Its storage conditions are really related to the stability and quality of this compound, and need to be carefully studied.
    This compound has active chemical properties and is extremely sensitive to many elements of the storage environment. First, temperature is crucial. It should be stored in a cool place to prevent excessive temperature from causing it to decompose or causing unnecessary chemical reactions. If placed in a high temperature environment, its molecular structure may change, and aldehyde groups, bromine atoms, and chlorine atoms may all participate in the reaction, which may damage the purity and integrity of the compound. Therefore, in a low temperature environment, generally speaking, between 0 ° C and 10 ° C. This temperature range can effectively reduce the active level of molecules and delay possible deterioration.
    Second, humidity cannot be ignored. This material is susceptible to moisture, water vapor or interaction with molecules, triggering reactions such as hydrolysis, and changing its chemical composition. Therefore, it must be stored in a dry place. It is better to maintain the dryness of the environment by means of auxiliary means such as desiccants, and control the relative humidity below 40%.
    Furthermore, light will also affect it. Light can provide energy, stimulate molecular reactions, and cause degradation or isomerization. Therefore, 2-bromo-5-chloropyridine-4-formaldehyde should be stored in a dark place, such as a brown bottle, or in a dark place to avoid adverse reactions caused by light.
    In addition, the choice of storage containers is also particular. Chemically stable materials, such as glass or specific plastic materials, should be used to prevent chemical reactions with the container and ensure that the quality of the compound is not affected by the container.
    In summary, 2-bromo-5-chloropyridine-4-formaldehyde should be stored in a cool, dry, dark place, choose a suitable storage container, and strictly control the temperature and humidity, so as to ensure the stability and purity of this substance during storage.