2 Bromo 5 Chloro 3 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Bromo-5-chloro-3-methylpyridine

    Specifications

    HS Code

    711198

    Chemical Formula C6H5BrClN
    Molar Mass 206.47 g/mol
    Appearance Solid (usually)
    Physical State At Room Temp Solid
    Boiling Point Data may vary, but typically high due to molecular weight
    Melting Point Data may vary
    Density Data may vary based on conditions
    Solubility In Water Low solubility, as it is an organic compound
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Odor Typically has an organic, pungent odor

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    General Information
    Where to Buy 2-Bromo-5-chloro-3-methylpyridine in China?
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    Frequently Asked Questions

    As a leading 2-Bromo-5-chloro-3-methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-Bromo-5-chloro-3-methylpyridine?
    2-Bromo-5-chloro-3-methylpyridine is one of the organic compounds. The physical properties of this substance are particularly important, and I will describe them in detail today.
    First of all, its appearance, under room temperature and pressure, 2-bromo-5-chloro-3-methylpyridine is often colorless to light yellow liquid. Its color is pure, and there is no noise. It is pure when viewed.
    As for the boiling point, the boiling point of this compound is quite high. Due to the intermolecular force, more energy is required to make it boil and vaporize. Such a high boiling point allows it to maintain a stable liquid state in an ordinary temperature environment.
    Melting point is also one of its characteristics. Its melting point is specific. When the temperature drops to a certain exact value, the substance will gradually turn from liquid to solid. The value of this melting point is its inherent physical property and can be used as one of the aids in the identification of the substance.
    In terms of density, 2-bromo-5-chloro-3-methyl pyridine has a specific density. This density makes it in a liquid mixed system, depending on the density, either floating on the top or sinking on the bottom. This property is quite practical in chemical separation and other operations.
    Solubility cannot be ignored. In organic solvents, such as ethanol, ether, etc., its solubility is quite good. Due to the principle of similar miscibility, its molecular structure is compatible with organic solvents, so it can be mutually soluble. However, in water, its solubility is poor, and the force between water and the organic molecule is weak, making it difficult to disperse it uniformly in water.
    2-bromo-5-chloro-3-methyl pyridine has the above physical properties, and it has unique uses in many fields such as organic synthesis. It can add bricks and mortar to the chemical industry and scientific research.
    What are the chemical properties of 2-Bromo-5-chloro-3-methylpyridine?
    2-Bromo-5-chloro-3-methylpyridine is one of the organic compounds. Its chemical properties are unique and have the common characteristics of halogenated pyridine compounds.
    As far as nucleophilic substitution is concerned, both bromine and chlorine in this compound are halogen atoms, which can be attacked and replaced by nucleophiles. Because the activity of bromine atoms is slightly higher than that of chlorine atoms, nucleophiles are more likely to interact with the position of bromine atoms, and bromine is replaced and left to form new substitution products. For example, if sodium alcohol is used as a nucleophilic reagent, corresponding ether derivatives can be formed.
    In the reduction reaction, the pyridine ring can be reduced under specific conditions. If a strong reducing agent is used, the unsaturated double bond of the pyridine ring can be added to the hydrogen atom, causing the electron cloud density of the ring to change, which affects its chemical activity and physical properties.
    Under acidic conditions, 2-bromo-5-chloro-3-methylpyridine may protonate, and the nitrogen atom of the pyridine ring can bind protons, changing the charge distribution and polarity of the molecule, which affects its solubility and reactivity.
    In an alkaline environment, halogen atoms may participate in the elimination reaction. If the strength of the base is appropriate, bromine or chlorine atoms can leave together with hydrogen atoms on adjacent carbon atoms to form unsaturated bonds, resulting in new double-bond-containing compounds.
    In addition, the methyl group of 2-bromo-5-chloro-3-methylpyridine can undergo oxidation reaction under appropriate conditions to form oxidation products such as carboxyl or aldehyde groups. The chemical properties of this compound vary depending on the reaction conditions and the types of reagents, and have important applications in the field of organic synthesis.
    What are the common synthetic methods of 2-Bromo-5-chloro-3-methylpyridine?
    2-Bromo-5-chloro-3-methylpyridine is also an organic compound. The common synthesis methods are about the following numbers.
    First, 3-methylpyridine is used as the starting material. First, 3-methylpyridine is reacted with chlorine under suitable conditions, and chlorine atoms can be introduced. This reaction requires the selection of a suitable catalyst, such as an iron-based catalyst, and the temperature and time of the reaction are controlled, so that the chlorine atom is mainly replaced in the fifth position of the pyridine ring to obtain 5-chloro-3-methylpyridine. Then, 5-chloro-3-methylpyridine is reacted with bromine in a specific reaction system. In this step, it is often necessary to add appropriate initiators, such as benzoyl peroxide, to promote the substitution of bromine atoms in the second position, so as to obtain 2-bromo-5-chloro-3-methylpyridine.
    Second, other compounds containing pyridine structures can also be used as starting materials. For example, select a pyridine derivative with a suitable substituent and pass through a series of functional group conversion reactions. First modify the original substituent to make it an active group that is easy to further react, and then introduce bromine atoms and chlorine atoms in turn through halogenation reactions. In this process, the reaction conditions, such as pH, temperature, solvent, etc., need to be carefully adjusted to ensure the selectivity and yield of the reaction.
    Or, the coupling reaction strategy of metal catalysis is used. First prepare a substrate containing a pyridine structure with a suitable leaving group, and couple it with a bromine-containing and chlorine-containing reagent under the action of a metal catalyst. This method requires high requirements for the selection of catalysts, the design of ligands, and the optimization of the reaction system. However, if properly operated, the target product can be synthesized efficiently.
    All these synthesis methods have their own advantages and disadvantages, and must be carefully selected according to actual conditions, such as the availability of raw materials, the difficulty of the reaction, and the consideration of cost.
    2-Bromo-5-chloro-3-methylpyridine in what areas
    2-Bromo-5-chloro-3-methylpyridine is used in various fields. In the field of pharmaceutical synthesis, it is often an important intermediate. Given the unique structure of this compound, it can introduce different functional groups through many reactions, and then construct molecules with specific biological activities. For example, when developing antibacterial drugs, by modifying its structure, new antibacterial agents may be created to fight drug-resistant strains and provide new options for clinical treatment.
    In the field of pesticide research and development, 2-bromo-5-chloro-3-methylpyridine is also of great value. It can be used as a starting material to synthesize pesticides with high insecticidal, bactericidal or herbicidal properties. By delicately designing the reaction path, the prepared pesticide is endowed with a unique mechanism of action, enhancing the activity of target organisms and reducing the impact on non-target organisms, achieving the purpose of green environmental protection and high efficiency.
    Furthermore, in the field of materials science, this compound may participate in the synthesis of functional materials. After a specific chemical reaction, it is integrated into the polymer material structure, which may endow the material with special optical and electrical properties. For example, when preparing organic optoelectronic materials, its structural properties may optimize the charge transport performance of the material and improve the application efficiency of the material in Light Emitting Diode, solar cells and other devices.
    And in the preparation of fine chemical products, 2-bromo-5-chloro-3-methylpyridine can be used to synthesize special fragrances, dyes, etc. After chemical modification, the product is endowed with unique color and aroma characteristics to meet the diverse needs of the market for high-quality fine chemical products.
    In summary, 2-bromo-5-chloro-3-methylpyridine has many uses in medicine, pesticides, materials science and fine chemicals, which cannot be ignored. It provides an important chemical basis for promoting technological innovation and development in various fields.
    What is the market price range for 2-Bromo-5-chloro-3-methylpyridine?
    I don't know how to cut the 2-Bromo-5-chloro-3-methylpyridine market. However, if you want to know the market value of this product, you can ask for it all the way.
    First, search on the chemical raw material trading platform. This platform lists multi-chemical product quality information, and may be able to get 2-Bromo-5-chloro-3-methylpyridine in the near future. However, it may vary due to quantity, supplier, and geographical factors.
    Second, it is suitable for chemical product suppliers. Direct suppliers can be expensive. Different suppliers have different cost and profit considerations, and there are also discounts. And large quantities or discounts.
    Third, it is necessary to report to the examination bank and analyze the materials in the market. It is necessary to report or contain specific chemical products, and the supply and demand of the market will help to roughly judge the quality of 2-Bromo-5-chloro-3-methylpyridine. However, due to the instantaneous situation of the city, the information is not up-to-date or not.

    In order to know the quality of the city, it is advisable to explore it in multiple ways and consider various factors in combination to obtain the quality of the product.