2 Bromo 4 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-bromo-4-(trifluoromethyl)pyridine

    Specifications

    HS Code

    529360

    Chemical Formula C6H3BrF3N
    Molecular Weight 226.009
    Appearance colorless to light yellow liquid
    Boiling Point 165 - 167 °C
    Melting Point N/A
    Density 1.669 g/mL at 25 °C
    Solubility Soluble in organic solvents like dichloromethane, chloroform
    Flash Point 64.4 °C
    Purity Typically high - 95%+ in commercial products
    Odor Pungent odor

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    General Information
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    Frequently Asked Questions

    As a leading 2-bromo-4-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-bromo-4- (trifluoromethyl) pyridine?
    2-% hydroxyl-4- (triethylmethyl) pyridine is one of the organic compounds. Its physical properties are unique, and I will tell you in detail.
    Looking at its properties, under normal temperature and pressure, it is mostly a colorless to light yellow transparent liquid, which is its intuitive appearance. Its smell is unique and slightly irritating, and it can be felt when smelled.
    When it comes to boiling point, it is about a certain numerical range, and this property is related to its phase change under different temperature environments. When the external temperature reaches the corresponding boiling point, the substance is converted from liquid to gaseous state. This is the process of material gasification, which needs to be carefully considered when applied in many fields such as chemical industry. The melting point of
    is also an important physical parameter. Only by knowing its melting point can we know the temperature conditions required for the transformation of a substance from a solid state to a liquid state, which is of great significance for its storage, transportation and application. The melting point of this substance also has a specific value.
    In terms of solubility, it has good solubility in some organic solvents, such as ethanol and ether, and can dissolve with it to form a uniform system. However, in water, its solubility may be different, slightly soluble, or insoluble. This property is related to the hydrophilicity and hydrophobicity of each group in its molecular structure.
    Density is also a key factor in characterizing its physical properties. Under certain conditions, its density value is relatively fixed. This value can be used to distinguish this substance from other similar substances, and also plays an important role in related process calculations.
    In addition, the refractive index of this substance is also one of its physical properties. When light passes through the substance, it will refract, and the refractive index reflects the degree to which the direction of light propagates in it changes. This property is often used in the detection of material purity and so on.
    In summary, the physical properties of 2-hydroxy- 4- (triethylmethyl) pyridine cover many aspects such as properties, odor, boiling point, melting point, solubility, density, refractive index, etc. All properties are interrelated and have far-reaching impact on its application in scientific research, industrial production and other fields.
    What are the main uses of 2-bromo-4- (trifluoromethyl) pyridine?
    2-% arsine-4- (triethylmethyl) pyridine is an organic compound. Its main uses are as follows:
    First, in the field of medicinal chemistry, this compound can be used as a key intermediate. Because the pyridine ring structure is ubiquitous in many drug molecular structures, and specific substituents can endow molecules with unique biological activities. For example, by chemically modifying and derivatizing it, new drugs with antibacterial, antiviral, and anti-tumor effects may be developed. Taking a study as an example, researchers have successfully developed a lead compound that exhibits significant inhibitory activity on specific tumor cell lines by introducing specific functional groups on the basis of this compound, opening up a new direction for the development of anti-tumor drugs.
    Second, in the field of materials science, 2-% arsine-4- (triethylmethyl) pyridine may be used to prepare materials with special properties. Due to its good coordination ability and electronic properties, pyridine compounds can be used as ligands to coordinate with metal ions to construct metal organic framework materials (MOFs). Such materials have potential application value in gas adsorption and separation, catalysis, etc. If relevant experiments show that the MOFs materials prepared based on this compound exhibit high adsorption capacity and selectivity for carbon dioxide gas, and have great application prospects in the field of greenhouse gas capture.
    Third, in the field of organic synthesis, this compound, as a nitrogen-containing heterocyclic compound, can participate in a variety of organic reactions, such as nucleophilic substitution reactions, oxidation reactions, etc., for the synthesis of more complex organic molecules. With its unique electronic effect and steric resistance, it can effectively regulate reaction selectivity and activity, providing organic synthesis chemists with rich strategies and methods to assist in the synthesis of novel organic compounds with specific functions.
    What are the synthesis methods of 2-bromo-4- (trifluoromethyl) pyridine?
    To prepare 2-hydroxy- 4 - (triethylmethyl) pyridine, the method is as follows:
    First, it can be obtained from the condensation reaction of suitable aldides, ketones and ammonia. If aldides and ketones with specific structures are selected, they will react with ammonia under specific reaction conditions. Temperature, pressure and reaction time are controlled to make the carbonyl groups of aldides and ketones condensate with ammonia, and through a series of complex chemical changes, the target product can be formed. This process requires the selection of suitable catalysts to promote the smooth progress of the reaction and improve the yield and selectivity.
    Second, it can also be modified by existing pyridine derivatives. To find a suitable parent of pyridine, use a specific chemical reaction to substitution it at a specific position. With ingenious design, the substituents are gradually introduced to precisely construct the structure of 2-hydroxy- 4- (triethyl) pyridine. This requires a good understanding of the reactivity and reaction laws of pyridine derivatives, and rational planning of reaction steps to avoid unnecessary side reactions.
    Third, some natural products can be considered as starting materials. Natural products have diverse structures or have a skeleton similar to the target product. After appropriate extraction, separation and chemical transformation, their structures are modified and modified to transform into 2-hydroxy- 4- (triethyl) pyridine. This approach requires in-depth understanding of natural product chemistry, and the sources of natural products may be limited, so the sustainability of raw material supply needs to be carefully considered.
    All these methods have their own advantages and disadvantages. In practical application, when considering various factors such as raw material availability, cost, difficulty of reaction conditions, and yield, the optimal method is selected for synthesis.
    What are the precautions for storing and transporting 2-bromo-4- (trifluoromethyl) pyridine?
    When storing and transporting 2-% cyanogen-4- (triethylmethyl) pyridine, it is necessary to pay attention to many key matters.
    First, because of its certain toxicity, it is related to personal safety. When storing, it is necessary to choose a well-ventilated and dry warehouse. It is strictly forbidden to mix with food, beverages, feed and other items to prevent accidental contact and ingestion. When transporting, transporters also need to be equipped with corresponding protective equipment, such as gas masks, protective clothing, etc., and transportation vehicles should also ensure sealing to prevent leakage.
    Second, this substance is potentially harmful to the environment or exists. During storage, there should be perfect anti-leakage measures, such as laying anti-penetration materials on the floor of the warehouse and setting up cofferdams around it. Once leakage occurs, the pollution range can be effectively controlled. During transportation, if you accidentally leak, you need to start an emergency plan immediately, properly collect and deal with the leakage, and avoid flowing into the soil, water and other environments.
    Third, temperature and humidity have a great impact on its stability. When storing, the warehouse temperature should be controlled within a specific range. Generally speaking, it is better to 5 ° C to 30 ° C, and the humidity should be kept at 40% to 70%. It is necessary to regularly monitor and regulate the temperature and humidity of the warehouse, and configure a temperature and humidity meter and corresponding control equipment. When transporting, you should also pay attention to avoid the impact of severe changes in external temperature and humidity. For example, when transporting during high temperatures in summer, vehicles should have good insulation measures. When it is low in winter, it is necessary to prevent packaging damage due to freezing.
    Fourth, the packaging must be solid and reliable. When storing, the packaging materials used must be able to effectively block air, moisture, etc., and have certain compression and drop resistance properties to prevent danger caused by package damage. During transportation, the packaging should be carefully checked to ensure that the packaging will not be loose or broken during long-distance transportation and handling. If glass bottle packaging is used, it needs to be reinforced with wooden boxes, etc., and the interior is filled with cushioning materials.
    What is the market price range for 2-bromo-4- (trifluoromethyl) pyridine?
    Wen Jun inquired about the market price range of 2-chloro-4- (triethylmethyl) pyridine. This compound is widely used in various industrial fields today, so its price is also influenced by many factors.
    As far as its market circulation is concerned, if it is of ordinary purity and suitable for general industrial use, its price is roughly between X yuan and Y yuan per kilogram. Products of this purity grade are widely used in common chemical synthesis processes and can meet the needs of most general production.
    However, if the purity requirements are strict and reach a high purity level, it is mostly used in high-precision fields such as pharmaceutical research and development and fine chemicals, and its price will rise sharply. Such high-purity 2-chloro-4- (triethylmethyl) pyridine, the price per kilogram may be above Z yuan. Because the preparation of high-purity products requires more complicated processes and stricter quality control, the cost will also increase sharply, resulting in high prices.
    In addition, the market supply and demand situation is also a key factor affecting its price. If the market demand is strong and the supply is relatively short, the price will rise; conversely, if the market supply is abundant and the demand is weak, the price may decline.
    The fluctuation of raw material prices, the innovation of production technology, and the change of policies and regulations will all affect the market price of 2-chloro-4- (triethylmethyl) pyridine. Therefore, its price is difficult to say in a word, and it needs to be determined comprehensively according to specific time and space situations, product specifications and many other factors.